نتائج البحث

Isophosphoramide mustard analogues as prodrugs for anticancer gene-directed enzyme-prodrug therapy (GDEPT)

• Authors : Misiura K; Szymanowicz D; Kuśnierczyk H

Subjects: Leukemia; Nucleotides; Carcinoma

• Source: Scopus-ElsevierEurope PubMed Central

تفاصيل العنوان

Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancer

• Authors : Preetinder Pal Singh; Pamela J. Russell; Swapna Joshi

Subjects: Proteomics; Cancer Research; medicine.medical_treatment

• Source: BMC CancerBMC Cancer, Vol 11, Iss 1, p 368 (2011)

تفاصيل العنوان

Dendrimers as Non-Viral Vectors in Gene-Directed Enzyme Prodrug Therapy.

• Authors : Chis AA; Preclinical Department, Faculty of Medicine, 'Lucian Blaga' University of Sibiu, 550169 Sibiu, Romania.; Dobrea CM

Subjects: Dendrimers/Dendrimers/Dendrimers/*pharmacology ; Genetic Therapy/Genetic Therapy/Genetic Therapy/*methods ; Prodrugs/Prodrugs/Prodrugs/*pharmacology

• Source: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 01; Vol. 26 (19). Date of Electronic Publication: 2021 Oct 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

تفاصيل العنوان

Polymeric Nanovectors Incorporated with Ganciclovir and HSV- tk Encoding Plasmid for Gene-Directed Enzyme Prodrug Therapy.

• Authors : Sawdon AJ; Department of Chemical Engineering, Michigan Technological University, Houghton, MI 49931, USA.; Zhang J

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/metabolism ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

• Source: Molecules (Basel, Switzerland) [Molecules] 2021 Mar 21; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

تفاصيل العنوان

Recombinant horseradish peroxidase variants for targeted cancer treatment.

• Authors : Bonifert G; Research Area Biochemical Engineering, Institute of Chemical Engineering, Vienna University of Technology, Vienna, Austria.; Folkes L

Subjects: Prodrugs*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Horseradish Peroxidase/Horseradish Peroxidase/Horseradish Peroxidase/*pharmacology

• Source: Cancer medicine [Cancer Med] 2016 Jun; Vol. 5 (6), pp. 1194-203. Date of Electronic Publication: 2016 Mar 15.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print-Electronic Cited Medium: Internet

تفاصيل العنوان

Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility.

• Authors : Williams, Elsie M.¹; Little, Rory F.¹; Mowday, Alexandra M.²

Subjects: *CANCER treatment; *GENE therapy; *NITROREDUCTASES

• Source: Biochemical Journal. 10/15/2015, Vol. 471 Issue 2, p131-150. 23p.

تفاصيل العنوان

Development of a Bioluminescent Nitroreductase Probe for Preclinical Imaging.

• Authors : Vorobyeva, Anzhelika G.¹; Stanton, Michael²; Godinat, Aurélien¹

Subjects: *BIOLUMINESCENCE; *NITROREDUCTASES; *DRUG development

• Source: PLoS ONE. Jun2015, Vol. 10 Issue 6, p1-18. 18p.

تفاصيل العنوان

The Flavin Reductase MsuE Is a Novel Nitroreductase that Can Efficiently Activate Two Promising Next-Generation Prodrugs for Gene-Directed Enzyme Prodrug Therapy.

• Authors : Green, Laura K.¹; Storey, Mathew A.¹; Williams, Elsie M.^1,2

• Source: Cancers. Sep2013, Vol. 5 Issue 3, p985-997. 13p.

تفاصيل العنوان

Carboxypeptidase-G2-based gene-directed enzyme-prodrug therapy: a new weapon in the GDEPT armoury.

• Authors : Hedley, Douglas¹; Ogilvie, Lesley¹; Springer, Caroline¹

• Source: Nature Reviews Cancer. Nov2007, Vol. 7 Issue 11, p870-879. 10p. 1 Illustration, 3 Diagrams, 4 Charts, 1 Graph.

تفاصيل العنوان

Gene-directed enzyme prodrug therapy with carboxylesterase enhances the anticancer efficacy of the conditionally replicating adenovirus AdΔ24.

• Authors : Oosterhoff, D.¹; Pinedo, H. M.¹; Witlox, M. A.¹

• Source: Gene Therapy. Jun2005, Vol. 12 Issue 12, p1011-1018. 8p.

تفاصيل العنوان