Authors : Kasparek P; Laboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., Vestec, Czech Republic.; Faculty of Sciences, Charles University in Prague, Prague, Czech Republic.

Subjects: Phenotype*; Kallikreins/Kallikreins/Kallikreins/*genetics ; Netherton Syndrome/Netherton Syndrome/Netherton Syndrome/*genetics

Source: PLoS genetics [PLoS Genet] 2017 Jan 17; Vol. 13 (1), pp. e1006566. Date of Electronic Publication: 2017 Jan 17 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.

Authors : Mizuno S; Laborarory Animal Resource Center, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.; Takami K

Subjects: Chromosome Deletion* ; Gene Deletion* ; Genes, Lethal*

Source: Scientific reports [Sci Rep] 2015 Sep 08; Vol. 5, pp. 13632. Date of Electronic Publication: 2015 Sep 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Aberrant activation of the human sex-determining gene in early embryonic development results in postnatal growth retardation and lethality in mice

Authors : Kido, Tatsuo; Sun, Zhaoyu; Lau, Yun-Fai Chris

Subjects: Biological Sciences; Biomedical and Clinical Sciences; Genetics

Source: Scientific Reports. 7(1)

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Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy

Authors : Jieqiong You; Bo Yang; Ji Cao

Subjects: Synthetic lethality; Poly ADP ribose polymerase; Review

Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2738-2748 (2021)Acta Pharmaceutica Sinica. B

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A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans.

Authors : Seidel, Hannah S; Ailion, Michael; Li, Jialing

Subjects: Muscles; Spermatozoa; Epidermis

Source: PLoS biology. 9(7)

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A CC-NBS-LRR gene induces hybrid lethality in cotton

Authors : Baoliang Zhou; Jieqiong Deng; Xiefei Zhu

Subjects: 0106 biological sciences; 0301 basic medicine; autoimmunity response

Source: Journal of Experimental Botany

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Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway

Authors : Junji Ishida; Satoru Takahashi; Kazuya Murata

Subjects: 0301 basic medicine; p53; QH301-705.5

Source: eLife, Vol 10 (2021)Dinh, T T H, Iseki, H, Mizuno, S, Lijima-Mizuno, S, Tanimoto, Y, Daitoku, Y, Kato, K, Hamada, Y, Hasan, A S H, Suzuki, H, Murata, K, Muratani, M, Ema, M, Kim, J-D, Ishida, J,

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Genetic landscape of T cells identifies synthetic lethality for T-ALL

Authors : Thomas Boehm; Katarzyna Sikora; Sarah Peter

Subjects: Positional cloning; QH301-705.5; T-Lymphocytes

Source: Communications BiologyCommunications Biology, Vol 4, Iss 1, Pp 1-18 (2021)

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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

Authors : Ishwar N. Kohale; Joshua J. Corrigan; Ilana S. Nazari

Subjects: 0301 basic medicine; DNA Replication; Nitrosamines

Source: Cell RepElsevier

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Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors

Authors : Katrina M. Lappin; Eliana M. Barros; Satpal S. Jhujh

Subjects: DNA Replication; Cancer Research; Poly(ADP-ribose) Polymerase Inhibitors

Source: Lappin, K M, Barros, E M, Jhujh, S S, Irwin, G W, McMillan, H, Liberante, F G, Latimer, C, LaBonte, M J, Mills, K I, Harkin, D P, Stewart, G S & Savage, K I 2022, ' Cancer-Associated SF3B1 Mutations

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نتائج البحث

فلترة النتائج

KLK5 and KLK7 Ablation Fully Rescues Lethality of Netherton Syndrome-Like Phenotype.

Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation.

Aberrant activation of the human sex-determining gene in early embryonic development results in postnatal growth retardation and lethality in mice

Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy

A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans.

A CC-NBS-LRR gene induces hybrid lethality in cotton

Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway

Genetic landscape of T cells identifies synthetic lethality for T-ALL

Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors

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