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Base-Labile Safety-Catch Linker: Synthesis and Applications in Solid-Phase Peptide Synthesis.

• Authors : Noki S; Peptide Science Laboratory, School of Chemistry and Physics, University of KwaZulu-Natal, Westville, Durban 4000, South Africa.; School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa.

Subjects: Solid-Phase Synthesis Techniques*/Solid-Phase Synthesis Techniques*/Solid-Phase Synthesis Techniques*/methods ; Peptides*/Peptides*/Peptides*/chemistry ; Peptides*/Peptides*/Peptides*/chemical synthesis

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 Feb 28; Vol. 26 (5). Date of Electronic Publication: 2025 Feb 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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C-28 linker length modulates the activity of second-generation HIV-1 maturation inhibitors.

• Authors : KC, Yuvraj¹ (AUTHOR); Singh, Aradhana¹ (AUTHOR); Datta, Sayantani¹ (AUTHOR)

• Source: Virology Journal. 3/22/2025, Vol. 22 Issue 1, p1-7. 7p.

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Revealing the Indispensable Role of the RFamide Functionality using a Novel Acid Labile Benzofuranone based Amine (ALBA) Linker.

• Authors : Mudd, Gemma¹ (AUTHOR); Hendrikse, Megan² (AUTHOR); Shave, Steven¹ (AUTHOR)

• Source: Helvetica Chimica Acta. Apr2024, Vol. 107 Issue 4, p1-7. 7p.

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Peptide Linker Affecting the Activity Retention Rate of VHH in Immunosorbents.

• Authors : Li D; Liaoning Key Laboratory of Molecular Recognition and imaging, School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian 116023, China.; Ren J

Subjects: Immunosorbents/Immunosorbents/Immunosorbents/*chemistry ; Peptides/Peptides/Peptides/*chemistry ; Single-Domain Antibodies/Single-Domain Antibodies/Single-Domain Antibodies/*chemistry

• Source: Biomolecules [Biomolecules] 2020 Nov 27; Vol. 10 (12). Date of Electronic Publication: 2020 Nov 27.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker.

• Authors : Miyazaki H; Medical Device Division, Innovation and Business Development Headquarters, Daicel Corporation, Minato-ku, Tokyo 108-8230, Japan.; Samejima Y

Subjects: Allergens/Allergens/Allergens/*analysis ; Animal Testing Alternatives/Animal Testing Alternatives/Animal Testing Alternatives/*methods ; Peptides/Peptides/Peptides/*analysis

• Source: International journal of molecular sciences [Int J Mol Sci] 2020 Nov 06; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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The flexible linker and CotG were more effective for the spore surface display of keratinase KERQ7.

• Authors : Wang, Zhen¹ (AUTHOR); Yan, Mingchen¹ (AUTHOR); Saeed, Muhammad¹ (AUTHOR)

Subjects: *BACILLUS subtilis; *SPORES; *COAT proteins (Viruses)

• Source: World Journal of Microbiology & Biotechnology. Jan2024, Vol. 40 Issue 1, p1-13. 13p.

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Peptide nucleic acid Hoogsteen strand linker design for major groove recognition of DNA thymine bases.

• Authors : Topham CM; Molecular Forces Consulting, 24 Avenue Jacques Besse, 81500, Lavaur, France. .; Computational Molecular Biophysics, IWR Der Universität Heidelberg, Im Neuenheimer Feld 368, 69120, Heidelberg, Germany. .

Subjects: DNA/DNA/DNA/*chemistry ; Peptide Nucleic Acids/Peptide Nucleic Acids/Peptide Nucleic Acids/*chemistry ; Peptides/Peptides/Peptides/*chemistry

• Source: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2021 Mar; Vol. 35 (3), pp. 355-369. Date of Electronic Publication: 2021 Feb 24.Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Evaluation of Met-Val-Lys as a Renal Brush Border Enzyme-Cleavable Linker to Reduce Kidney Uptake of 68 Ga-Labeled DOTA-Conjugated Peptides and Peptidomimetics.

• Authors : Bendre S; Department of Molecular Oncology, BC Cancer, Vancouver, BC V5Z 1L3, Canada.; Zhang Z

Subjects: Gallium Radioisotopes*/Gallium Radioisotopes*/Gallium Radioisotopes*/chemistry ; Gallium Radioisotopes*/Gallium Radioisotopes*/Gallium Radioisotopes*/pharmacokinetics ; Gallium Radioisotopes*/Gallium Radioisotopes*/Gallium Radioisotopes*/pharmacology

• Source: Molecules (Basel, Switzerland) [Molecules] 2020 Aug 25; Vol. 25 (17). Date of Electronic Publication: 2020 Aug 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Effect of linker on the binding free energy of stapled p53/HDM2 complex.

• Authors : Im H; Department of Chemistry, The Research Institute of Natural Sciences, Sookmyung Women's University, Seoul, Korea.; Ham S

Subjects: Peptides/Peptides/Peptides/*chemistry ; Proto-Oncogene Proteins c-mdm2/Proto-Oncogene Proteins c-mdm2/Proto-Oncogene Proteins c-mdm2/*chemistry ; Tumor Suppressor Protein p53/Tumor Suppressor Protein p53/Tumor Suppressor Protein p53/*chemistry

• Source: PloS one [PLoS One] 2020 Apr 30; Vol. 15 (4), pp. e0232613. Date of Electronic Publication: 2020 Apr 30 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Development of a Novel, Easy-to-Prepare, and Potentially Valuable Peptide Coupling Technology Utilizing Amide Acid as a Linker.

• Authors : Wang, Yaling^1,2,3 (AUTHOR) ; Yang, Fan^{2,3,4,5,6,7,8,9} (AUTHOR) ; Li, Hongyan¹⁰ (AUTHOR)

• Source: Pharmaceuticals (14248247). Aug2024, Vol. 17 Issue 8, p981. 17p.

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