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Academic Journal

CRNDE alleviates IL-1β-induced chondrocyte damage by modulating miR-31/NF-κB pathway.

Authors : Liu J; Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University (Jiangsu Province Hospital), No. 300 Guangzhou Road, NanjingJiangsu Province, 210029, China. .; Cheng J

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/drug effects ; Chondrocytes*/Chondrocytes*/Chondrocytes*/pathology

Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2024 Dec 19; Vol. 19 (1), pp. 860. Date of Electronic Publication: 2024 Dec 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X

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Academic Journal

Hypoxia-induced activation of HIF-1alpha/IL-1beta axis in microglia promotes glioma progression via NF-κB-mediated upregulation of heparanase expression.

Authors : Si J; Department of Neurology, the Second Affiliated Hospital of Zhengzhou University, Zhengzhou, 450014, China.; Guo J

Subjects: Glioma*/Glioma*/Glioma*/metabolism ; Glioma*/Glioma*/Glioma*/genetics ; Glioma*/Glioma*/Glioma*/pathology

Source: Biology direct [Biol Direct] 2024 Jun 11; Vol. 19 (1), pp. 45. Date of Electronic Publication: 2024 Jun 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101258412 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6150

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Academic Journal

Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression in three-dimensional culture which can be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signaling.

Authors : Beaumont RE; Clinical Sciences and Service, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, AL9 7TA, Herts, UK. .; Smith EJ

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; Interleukin-1beta*/Interleukin-1beta*/Interleukin-1beta*/metabolism ; Interleukin-1beta*/Interleukin-1beta*/Interleukin-1beta*/pharmacology

Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2024 May; Vol. 479 (5), pp. 1059-1078. Date of Electronic Publication: 2023 Jun 14.Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Arctigenin derivative A-1 ameliorates motor dysfunction and pathological manifestations in SOD1 G93A transgenic mice via the AMPK/SIRT1/PGC-1α and AMPK/SIRT1/IL-1β/NF-κB pathways.

Authors : Xiong B; Shenzhen Key Laboratory of Modern Toxicology, Shenzhen Medical Key Discipline of Health Toxicology (2020-2024), Shenzhen Center for Disease Control and Prevention, Shenzhen, China.; Yang C

Subjects: Mice, Transgenic* ; Sirtuin 1*/Sirtuin 1*/Sirtuin 1*/metabolism ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism

Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 Jun; Vol. 30 (6), pp. e14692.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949

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Academic Journal

Evaluation of the effect of phellodendrin application on rats creating an experimental model of non-compression lumbar disc herniation on the NF-κB-related inflammatory signaling pathway.

Authors : Tan P; Department of Orthopaedics, People's Hospital of Linshui, Linshui, 638500, China. .; Mei J

Subjects: Intervertebral Disc Displacement*/Intervertebral Disc Displacement*/Intervertebral Disc Displacement*/metabolism ; Intervertebral Disc Displacement*/Intervertebral Disc Displacement*/Intervertebral Disc Displacement*/drug therapy ; Rats, Sprague-Dawley*

Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2024 Dec 03; Vol. 19 (1), pp. 816. Date of Electronic Publication: 2024 Dec 03.Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X

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Academic Journal

Cinnamaldehyde-Mediated Suppression of MMP-13, COX-2, and IL-6 Through MAPK and NF-κB Signaling Inhibition in Chondrocytes and Synoviocytes Under Inflammatory Conditions.

Authors : Sankaranarayanan J; Department of Biomedical Sciences, Chonnam National University Medical School, Hwasun 58128, Jeollanam-do, Republic of Korea.; Department of Orthopaedic Surgery, Center for Joint Disease of Chonnam National University Hwasun Hospital, 322 Seoyang-ro, Hwasun 519-763, Jeollanam-do, Republic of Korea.

Subjects: Chondrocytes*/Chondrocytes*/Chondrocytes*/drug effects ; Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 30; Vol. 25 (23). Date of Electronic Publication: 2024 Nov 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Eriodictyol attenuates osteoarthritis progression through inhibiting inflammation via the PI3K/AKT/NF-κB signaling pathway.

Authors : Kang W; Department of Orthopedics, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun, 130033, People's Republic of China.; Xu Q

Subjects: Flavanones*/Flavanones*/Flavanones*/pharmacology ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism

Source: Scientific reports [Sci Rep] 2024 Aug 14; Vol. 14 (1), pp. 18853. Date of Electronic Publication: 2024 Aug 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Olprinone, a Selective Phosphodiesterase III Inhibitor, Has Protective Effects in a Septic Rat Model after Partial Hepatectomy and Primary Rat Hepatocyte.

Authors : Kotsuka M; Department of Surgery, Kansai Medical University, Hirakata 573-1010, Japan.; Okuyama T

Subjects: Hepatectomy*/Hepatectomy*/Hepatectomy*/adverse effects ; Hepatocytes*/Hepatocytes*/Hepatocytes*/drug effects ; Hepatocytes*/Hepatocytes*/Hepatocytes*/metabolism

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 29; Vol. 25 (13). Date of Electronic Publication: 2024 Jun 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

REDD1 Deletion Suppresses NF-κB Signaling in Cardiomyocytes and Prevents Deficits in Cardiac Function in Diabetic Mice.

Authors : Stevens SA; Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, PA 17033, USA.; Sunilkumar S

Subjects: Myocytes, Cardiac*/Myocytes, Cardiac*/Myocytes, Cardiac*/metabolism ; NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Signal Transduction*

Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 12; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways.

Authors : Hong X; Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Jiangxi Province's Artificial Joints Engineering and Technology Research Center, Nanchang, 330006, Jiangxi Province, China.; Liu X

Subjects: NF-kappa B*/NF-kappa B*/NF-kappa B*/metabolism ; Osteoarthritis*/Osteoarthritis*/Osteoarthritis*/metabolism ; Diterpenes, Kaurane*

Source: Journal of orthopaedic surgery and research [J Orthop Surg Res] 2024 Mar 18; Vol. 19 (1), pp. 188. Date of Electronic Publication: 2024 Mar 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101265112 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-799X

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نتائج البحث

فلترة النتائج

CRNDE alleviates IL-1β-induced chondrocyte damage by modulating miR-31/NF-κB pathway.

Hypoxia-induced activation of HIF-1alpha/IL-1beta axis in microglia promotes glioma progression via NF-κB-mediated upregulation of heparanase expression.

Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression in three-dimensional culture which can be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signaling.

Arctigenin derivative A-1 ameliorates motor dysfunction and pathological manifestations in SOD1 G93A transgenic mice via the AMPK/SIRT1/PGC-1α and AMPK/SIRT1/IL-1β/NF-κB pathways.

Evaluation of the effect of phellodendrin application on rats creating an experimental model of non-compression lumbar disc herniation on the NF-κB-related inflammatory signaling pathway.

Cinnamaldehyde-Mediated Suppression of MMP-13, COX-2, and IL-6 Through MAPK and NF-κB Signaling Inhibition in Chondrocytes and Synoviocytes Under Inflammatory Conditions.

Eriodictyol attenuates osteoarthritis progression through inhibiting inflammation via the PI3K/AKT/NF-κB signaling pathway.

Olprinone, a Selective Phosphodiesterase III Inhibitor, Has Protective Effects in a Septic Rat Model after Partial Hepatectomy and Primary Rat Hepatocyte.

REDD1 Deletion Suppresses NF-κB Signaling in Cardiomyocytes and Prevents Deficits in Cardiac Function in Diabetic Mice.

Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways.

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