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Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits

• Authors : Saul Herranz-Martin; Jayanth Chandran; Katherine Lewis

Subjects: C9orf72; Neurodegeneration; ALS/FTD

• Source: Disease Models & Mechanisms, Vol 10, Iss 7, Pp 859-868 (2017)

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Proposed association between the hexanucleotide repeat of C9orf72 and opposability index of the thumb.

• Authors : Chen, Zhongbo¹ (AUTHOR); Lin, Kuang¹ (AUTHOR); Macklis, Jeffrey D.² (AUTHOR)

• Source: Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. May2017, Vol. 18 Issue 3/4, p175-181. 7p.

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Different CSF protein profiles in amyotrophic lateral sclerosis and frontotemporal dementia with C9orf72 hexanucleotide repeat expansion

• Authors : Barschke, Peggy; Oeckl, Patrick; Steinacker, Petra

Subjects: Neurodegeneration

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G-Quadruplex Structures Formed by Expanded Hexanucleotide Repeat RNA and DNA from the Neurodegenerative Disease-Linked C9orf72 Gene Efficiently Sequester and Activate Heme.

• Authors : Grigg, Jason C.¹; Shumayrikh, Nisreen²; Sen, Dipankar^1,2

Subjects: *QUADRUPLEX nucleic acids; *NUCLEOTIDES; *NEURODEGENERATION

• Source: PLoS ONE. Sep2014, Vol. 9 Issue 9, p1-8. 8p.

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Viral delivery of C9ORF72 hexanucleotide repeat expansions in mice lead to repeat length dependent neuropathology and behavioral deficits

• Authors : Herranz Martín, Saúl; Azzouz, Mimoun

Subjects: 577.2; 616.8; C9orf72

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Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits

• Authors : Herranz-Martin, S; Chandran, J; Lewis, K

Subjects: ALS/FTD; C9RAN aggregates; C9orf72

• Source: Disease Models & Mechanisms , 10 (7) pp. 859-868. (2017)

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Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72

• Authors : Ismail, Azza; Cooper-Knock, Johnathan; Highley, J Robin

Subjects: Neurodegeneration

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Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72

• Authors : Ismail, Azza; Cooper-Knock, Johnathan; Highley, J Robin

Subjects: Neurodegeneration

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Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases

• Authors : Genin, Emmanuelle C.; Bannwarth, Sylvie; Lespinasse, Francoise ...

Subjects: CHCHD10; SMAJ; FTD-ALS

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C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers

• Authors : Rizzu, Patrizia; Blauwendraat, Cornelis; Heetveld, Sasja

Subjects: Neurodegeneration; C9orf72 risk haplotype; Hexanucleotide repeat expansion

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