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Academic Journal

Cancer Vulnerabilities Through Targeting the ATR/Chk1 and ATM/Chk2 Axes in the Context of DNA Damage.

  • Authors : Fernandez A; Program in Solid Tumors, CIMA, Cancer Center Clinica Universidad de Navarra (CCUN), University of Navarra, Avenida de Pio XII, 55, 31008 Pamplona, Spain.; Department of Pathology, Anatomy and Physiology, School of Medicine, University of Navarra, 31008 Pamplona, Spain.

Subjects: DNA Damage* ; Checkpoint Kinase 2*/Checkpoint Kinase 2*/Checkpoint Kinase 2*/metabolism ; Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/metabolism

  • Source: Cells [Cells] 2025 May 20; Vol. 14 (10). Date of Electronic Publication: 2025 May 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Pancancer analysis of DNA damage repair gene mutations and their impact on immune regulatory gene expression.

  • Authors : Yadav K; School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.; Das T

Subjects: DNA Repair*/DNA Repair*/DNA Repair*/genetics ; Mutation* ; DNA Damage*/DNA Damage*/DNA Damage*/genetics

  • Source: Scientific reports [Sci Rep] 2025 May 05; Vol. 15 (1), pp. 15667. Date of Electronic Publication: 2025 May 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Targeting DNA Damage Repair to Enhance Antitumor Immunity in Radiotherapy: Mechanisms and Opportunities.

  • Authors : Yang L; Department of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.; Wei W

Subjects: DNA Repair*/DNA Repair*/DNA Repair*/drug effects ; DNA Repair*/DNA Repair*/DNA Repair*/radiation effects ; Neoplasms*/Neoplasms*/Neoplasms*/immunology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Apr 16; Vol. 26 (8). Date of Electronic Publication: 2025 Apr 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cancer Development and Progression Through a Vicious Cycle of DNA Damage and Inflammation.

  • Authors : Kawanishi S; Department of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka 513-8670, Mie, Japan.; Wang G

Subjects: DNA Damage* ; Inflammation*/Inflammation*/Inflammation*/metabolism ; Inflammation*/Inflammation*/Inflammation*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Apr 03; Vol. 26 (7). Date of Electronic Publication: 2025 Apr 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Impact of glycolysis enzymes and metabolites in regulating DNA damage repair in tumorigenesis and therapy.

  • Authors : Sun F; Precision Medicine Laboratory for Chronic Non-Communicable Diseases of Shandong Province, Institute of Precision Medicine, Jining Medical University, Jining, 272067, China.; Li W

Subjects: Glycolysis* ; DNA Repair* ; Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/metabolism

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2025 Jan 23; Vol. 23 (1), pp. 44. Date of Electronic Publication: 2025 Jan 23.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants.

  • Authors : Vasquez CA; Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, CA 92093, United States.; Osgood NRB

Subjects: DNA Glycosylases*/DNA Glycosylases*/DNA Glycosylases*/genetics ; DNA Glycosylases*/DNA Glycosylases*/DNA Glycosylases*/metabolism ; DNA Repair*/DNA Repair*/DNA Repair*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Mar 20; Vol. 53 (6).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Expression quantitative trait loci influence DNA damage-induced apoptosis in cancer.

  • Authors : Bigge J; Philipps University of Marburg, Center for Human Genetics, Marburg, Germany.; Koebbe LL

Subjects: Quantitative Trait Loci* ; DNA Damage* ; Apoptosis*/Apoptosis*/Apoptosis*/genetics

  • Source: BMC genomics [BMC Genomics] 2024 Dec 02; Vol. 25 (1), pp. 1168. Date of Electronic Publication: 2024 Dec 02.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Unraveling the Guardian: p53's Multifaceted Role in the DNA Damage Response and Tumor Treatment Strategies.

  • Authors : Zhang H; Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830017, China.; Xu J

Subjects: DNA Damage* ; DNA Repair*/DNA Repair*/DNA Repair*/drug effects ; Neoplasms*/Neoplasms*/Neoplasms*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 01; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Quantitative evaluation of DNA damage repair dynamics to elucidate predictors of autism vs. cancer in individuals with germline PTEN variants.

  • Authors : Wei R; Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America.; Department of Nutrition and Systems Biology and Bioinformatics Program, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America.

Subjects: PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/PTEN Phosphohydrolase*/genetics ; DNA Repair*/DNA Repair*/DNA Repair*/genetics ; DNA Damage*/DNA Damage*/DNA Damage*/genetics

  • Source: PLoS computational biology [PLoS Comput Biol] 2024 Oct 02; Vol. 20 (10), pp. e1012449. Date of Electronic Publication: 2024 Oct 02 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Complex Interplay between DNA Damage and Autophagy in Disease and Therapy.

  • Authors : Singh A; Department of Medical Biophysics, Schulich School of Medicine and Dentistry, University of Western Ontario, 1151 Richmond Street North, London, ON N6A 5C1, Canada.; Ravendranathan N

Subjects: Autophagy*/Autophagy*/Autophagy*/drug effects ; DNA Damage* ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: Biomolecules [Biomolecules] 2024 Jul 29; Vol. 14 (8). Date of Electronic Publication: 2024 Jul 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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