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النتائج لكل صفحة: 10
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Subject : neoplasm proteins
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Academic Journal

Regulation of NF-κB by PML and PML-RARα.

  • Authors : Ahmed A; Department of Biochemistry, University College Cork, Cork, Ireland.; Wan X

Subjects: Gene Expression Regulation*; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*genetics ; Oncogene Proteins, Fusion/Oncogene Proteins, Fusion/Oncogene Proteins, Fusion/*genetics

  • Source: Scientific reports [Sci Rep] 2017 Mar 20; Vol. 7, pp. 44539. Date of Electronic Publication: 2017 Mar 20.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

MageA2 restrains cellular senescence by targeting the function of PMLIV/p53 axis at the PML-NBs.

  • Authors : Peche LY; Laboratorio Nazionale del Consorzio Interuniversitario per le Biotecnologie, Area Science Park, Padriciano 99, Trieste 34149, Italy.; Scolz M

Subjects: Cellular Senescence*; Intranuclear Inclusion Bodies/Intranuclear Inclusion Bodies/Intranuclear Inclusion Bodies/*metabolism ; Melanoma-Specific Antigens/Melanoma-Specific Antigens/Melanoma-Specific Antigens/*metabolism

  • Source: Cell death and differentiation [Cell Death Differ] 2012 Jun; Vol. 19 (6), pp. 926-36. Date of Electronic Publication: 2011 Nov 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway.

  • Authors : Lallemand-Breitenbach V; Université de Paris 7/CNRS UMR 7151, Equipe Labellisée N11 Ligue Nationale Contre le Cancer, Hôpital St. Louis, 1, Av. C. Vellefaux 75475 Paris CEDEX 10 France.; Jeanne M

Subjects: Arsenic/Arsenic/Arsenic/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

  • Source: Nature cell biology [Nat Cell Biol] 2008 May; Vol. 10 (5), pp. 547-55. Date of Electronic Publication: 2008 Apr 13.Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Editorial & Opinion

A new PML-RARs fusion transcript hints at the important role of PML dysregulation in the pathogenesis of APL.

  • Authors : Opalinska J; Albert Einstein College of Medicine, Bronx, NY 10461, USA.; Zhou L

Subjects: Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/*etiology ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

  • Source: Leukemia & lymphoma [Leuk Lymphoma] 2007 Mar; Vol. 48 (3), pp. 443-4.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print Cited Medium: Print ISSN: 1042-8194

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Academic Journal

Role of PML and the PML-nuclear body in the control of programmed cell death.

  • Authors : Bernardi R; Molecular Biology Program and Department of Pathology, Memorial Sloan-Kettering Cancer Center, Sloan-Kettering Division, Graduate School of Medical Sciences, Cornell University, 1275 York Avenue, New York, NY 10021, USA.; Pandolfi PP

Subjects: Apoptosis* ; Nuclear Proteins*; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*genetics

  • Source: Oncogene [Oncogene] 2003 Dec 08; Vol. 22 (56), pp. 9048-57.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.

  • Authors : Bernardi R; Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, Sloan-Kettering Institute, 1275 York Avenue, New York, New York 10021, USA.; Guernah I

Subjects: Neovascularization, Pathologic* ; Protein Biosynthesis*; Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/Hypoxia-Inducible Factor 1, alpha Subunit/*biosynthesis

  • Source: Nature [Nature] 2006 Aug 17; Vol. 442 (7104), pp. 779-85.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Leukemia with distinct phenotypes in transgenic mice expressing PML/RAR alpha, PLZF/RAR alpha or NPM/RAR alpha.

  • Authors : Rego EM; Cancer Biology and Genetics Program, Department of Pathology, Memorial Sloan-Kettering Cancer Center, Sloan Kettering Institute, New York, NY 10021, USA.; Ruggero D

Subjects: Gene Fusion*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics ; Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/Leukemia, Promyelocytic, Acute/*genetics

  • Source: Oncogene [Oncogene] 2006 Mar 23; Vol. 25 (13), pp. 1974-9.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts.

  • Authors : Cairo S; Telethon Institute of Genetics and Medicine, 80131 Naples, Italy.; De Falco F

Subjects: Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*genetics ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*genetics

  • Source: Oncogene [Oncogene] 2005 Mar 24; Vol. 24 (13), pp. 2195-203.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print Cited Medium: Print ISSN: 0950-9232

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Academic Journal

PML enhances the regulation of p53 by CK1 in response to DNA damage.

  • Authors : Alsheich-Bartok O; Department of Immunology, The Hebrew University Hadassah Medical School, Jerusalem, Israel.; Haupt S

Subjects: DNA Damage*; Casein Kinase I/Casein Kinase I/Casein Kinase I/*physiology ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*physiology

  • Source: Oncogene [Oncogene] 2008 Jun 12; Vol. 27 (26), pp. 3653-61. Date of Electronic Publication: 2008 Feb 04.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation.

  • Authors : Tatham MH; Wellcome Trust Centre for Gene Regulation and Expression, College of Life Sciences, University of Dundee, Dow Street, Dundee DD1 5EH, UK.; Geoffroy MC

Subjects: Arsenic/Arsenic/Arsenic/*metabolism ; Neoplasm Proteins/Neoplasm Proteins/Neoplasm Proteins/*metabolism ; Nuclear Proteins/Nuclear Proteins/Nuclear Proteins/*metabolism

  • Source: Nature cell biology [Nat Cell Biol] 2008 May; Vol. 10 (5), pp. 538-46. Date of Electronic Publication: 2008 Apr 13.Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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