نتائج البحث

NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy.

• Authors : Ranu, Natasha¹ (AUTHOR); Laitila, Jenni^2,3 (AUTHOR); Dugdale, Hannah F.^1,4 (AUTHOR)

• Source: Acta Neuropathologica Communications. 12/17/2022, p1-14. 14p.

تفاصيل العنوان

A Novel Variant in TPM3 Causing Muscle Weakness and Concomitant Hypercontractile Phenotype.

• Authors : Robaszkiewicz, Katarzyna¹ (AUTHOR) ; Siatkowska, Małgorzata¹ (AUTHOR) ; Wadman, Renske I.² (AUTHOR)

Subjects: *NEMALINE myopathy; *MUSCLE weakness; *MYOSIN

• Source: International Journal of Molecular Sciences. Nov2023, Vol. 24 Issue 22, p16147. 15p.

تفاصيل العنوان

NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy

• Authors : Ranu, Natasha; Laitila, Jenni; Dugdale, Hannah F. ...

Subjects: Metabolism; Myosin; Nebulin

تفاصيل العنوان

Structure of the Drosophila melanogaster Flight Muscle Myosin Filament at 4.7 Å Resolution Reveals New Details of Non-Myosin Proteins.

• Authors : Abbasi Yeganeh, Fatemeh¹ (AUTHOR) ; Rastegarpouyani, Hosna^1,2 (AUTHOR) ; Li, Jiawei¹ (AUTHOR)

Subjects: *DROSOPHILA melanogaster; *FIBERS; *STRIATED muscle

• Source: International Journal of Molecular Sciences. Oct2023, Vol. 24 Issue 19, p14936. 21p.

تفاصيل العنوان

Abnormal myosin post‐translational modifications and ATP turnover time associated with human congenital myopathy‐related RYR1 mutations.

• Authors : Sonne, Alexander¹ (AUTHOR); Antonovic, Anna Katarina² (AUTHOR); Melhedegaard, Elise¹ (AUTHOR)

• Source: Acta Physiologica. Oct2023, Vol. 239 Issue 2, p1-14. 14p. 2 Charts, 6 Graphs.

تفاصيل العنوان

Nemaline Myopathy-Related Skeletal Muscle α-Actin (ACTA1) Mutation, Asp286Gly, Prevents Proper Strong Myosin Binding and Triggers Muscle Weakness.

• Authors : Ochala, Julien¹ ; Ravenscroft, Gianina²; Laing, Nigel G.²

Subjects: *ACTIN; *PROTEIN genetics; *MUSCLE weakness

• Source: PLoS ONE. Sep2012, Vol. 7 Issue 9, Special section p1-6. 6p.

تفاصيل العنوان

NEB mutations disrupt the super-relaxed state of myosin and remodel the muscle metabolic proteome in nemaline myopathy

• Authors : Natasha Ranu; Jenni Laitila; Hannah Dugdale

Subjects: Biochemistry and cell biology; Clinical sciences; Neurosciences

تفاصيل العنوان

Molecular Mechanisms of Deregulation of Muscle Contractility Caused by the R168H Mutation in TPM3 and Its Attenuation by Therapeutic Agents.

• Authors : Karpicheva, Olga E.¹ (AUTHOR); Avrova, Stanislava V.¹ (AUTHOR); Bogdanov, Andrey L.¹ (AUTHOR)

Subjects: *MYOSIN; *NEMALINE myopathy; *MUSCLE weakness

• Source: International Journal of Molecular Sciences. Mar2023, Vol. 24 Issue 6, p5829. 24p.

تفاصيل العنوان

Varying thin filament activation in the framework of the Huxley'57 model.

• Authors : Kimmig, François^1,2 (AUTHOR) ; Caruel, Matthieu³ (AUTHOR); Chapelle, Dominique^1,2 (AUTHOR)

• Source: International Journal for Numerical Methods in Biomedical Engineering. Dec2022, Vol. 38 Issue 12, p1-20. 20p.

تفاصيل العنوان

Dominantly inherited myosin IIa myopathy caused by aberrant splicing of MYH2.

• Authors : Hedberg-Oldfors, Carola¹ (AUTHOR) ; Elíasdóttir, Ólöf² (AUTHOR); Geijer, Mats^3,4,5 (AUTHOR)

• Source: BMC Neurology. 11/15/2022, Vol. 22, p1-9. 9p.

تفاصيل العنوان