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Academic Journal

Mycophenolate Mofetil, an Inhibitor of Inosine Monophosphate Dehydrogenase, and Tofacitinib, a Janus Kinase Inhibitor, Attenuate Airway Inflammation and Hyperresponsiveness in a Mouse Model of Allergic Asthma.

  • Authors : Kravčenia B; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego Street 13, 10-719 Olsztyn, Poland.; Maślanka T

Subjects: Asthma*/Asthma*/Asthma*/drug therapy ; Disease Models, Animal* ; Piperidines*/Piperidines*/Piperidines*/pharmacology

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Nov 09; Vol. 29 (22). Date of Electronic Publication: 2024 Nov 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

A structural determinant of mycophenolic acid resistance in eukaryotic inosine 5'-monophosphate dehydrogenases.

  • Authors : Freedman R; Graduate Program in Biochemistry and Biophysics, Brandeis University, Waltham, Massachusetts.; Yu R

Subjects: Antifungal Agents/Antifungal Agents/Antifungal Agents/*pharmacology ; Drug Resistance, Fungal/Drug Resistance, Fungal/Drug Resistance, Fungal/*drug effects ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology

  • Source: Protein science : a publication of the Protein Society [Protein Sci] 2020 Mar; Vol. 29 (3), pp. 686-694. Date of Electronic Publication: 2019 Nov 20.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9211750 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Novel amides of mycophenolic acid and some heterocyclic derivatives as immunosuppressive agents.

Subjects: Immunosuppressive Agents*/Immunosuppressive Agents*/Immunosuppressive Agents*/chemistry ; Mycophenolic Acid*/Mycophenolic Acid*/Mycophenolic Acid*/chemistry; Amides/Amides/Amides/pharmacology

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2725-2741.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

The combination of exposure to Tacrolimus, mycophenolic acid, Inosine 5'-Monophosphate Dehydrogenase activity and inhibition in the first week define early histological outcomes in renal transplant recipients.

Subjects: Mycophenolic Acid*/Mycophenolic Acid*/Mycophenolic Acid*/therapeutic use ; Kidney Transplantation*/Kidney Transplantation*/Kidney Transplantation*/adverse effects; Humans

  • Source: Clinical transplantation [Clin Transplant] 2022 Dec; Vol. 36 (12), pp. e14830. Date of Electronic Publication: 2022 Oct 26.Publisher: Munksgaard Country of Publication: Denmark NLM ID: 8710240 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-0012

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Academic Journal

Inosine monophosphate dehydrogenase activity and mycophenolate pharmacokinetics in children with nephrotic syndrome treated with mycophenolate mofetil.

  • Authors : Sobiak J; Department of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, Poznan, Poland.; Resztak M

Subjects: Mycophenolic Acid*/Mycophenolic Acid*/Mycophenolic Acid*/therapeutic use ; Nephrotic Syndrome*/Nephrotic Syndrome*/Nephrotic Syndrome*/drug therapy; Adenosine Monophosphate

  • Source: Clinical and experimental pharmacology & physiology [Clin Exp Pharmacol Physiol] 2022 Nov; Vol. 49 (11), pp. 1197-1208. Date of Electronic Publication: 2022 Aug 29.Publisher: Wiley-Blackwell Country of Publication: Australia NLM ID: 0425076 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

A new class of IMP dehydrogenase with a role in self-resistance of mycophenolic acid producing fungi.

  • Authors : Hansen BG; Center for Microbial Biotechnology, Department of Systems Biology, Technical University of Denmark, 2800 Kgs Lyngby, Denmark.; Genee HJ

Subjects: Aspergillus nidulans/Aspergillus nidulans/Aspergillus nidulans/*drug effects ; Fungal Proteins/Fungal Proteins/Fungal Proteins/*metabolism ; IMP Dehydrogenase/IMP Dehydrogenase/IMP Dehydrogenase/*metabolism

  • Source: BMC microbiology [BMC Microbiol] 2011 Sep 16; Vol. 11, pp. 202. Date of Electronic Publication: 2011 Sep 16.Publisher: BioMed Central Country of Publication: England NLM ID: 100966981 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2180

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Academic Journal

IMP dehydrogenase basal activity in MOLT-4 human leukaemia cells is altered by mycophenolic acid and 6-thioguanosine.

  • Authors : Vethe NT; Department of Medical Biochemistry, Rikshospitalet Medical Centre, Oslo, Norway.; Bremer S

Subjects: Guanosine/Guanosine/Guanosine/*analogs & derivatives ; IMP Dehydrogenase/IMP Dehydrogenase/IMP Dehydrogenase/*metabolism ; Leukemia/Leukemia/Leukemia/*enzymology

  • Source: Scandinavian journal of clinical and laboratory investigation [Scand J Clin Lab Invest] 2008; Vol. 68 (4), pp. 277-85.Publisher: Informa Healthcare Country of Publication: England NLM ID: 0404375 Publication Model: Print Cited Medium: Print ISSN: 0036-5513

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Academic Journal

Newer human inosine 5'-monophosphate dehydrogenase 2 (hIMPDH2) inhibitors as potential anticancer agents.

  • Authors : Shah CP; a Department of Pharmaceutical Chemistry , SPP School of Pharmacy and Technology Management, SVKM's NMIMS , Mumbai , India.; Kharkar PS

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*pharmacology ; IMP Dehydrogenase/IMP Dehydrogenase/IMP Dehydrogenase/*antagonists & inhibitors

  • Source: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2018 Dec; Vol. 33 (1), pp. 972-977.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101150203 Publication Model: Print Cited Medium: Internet ISSN: 1475-6374

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Academic Journal

Mycophenolate mofetil and atopic dermatitis: systematic review and meta-analysis.

  • Authors : Phan K; Department of Dermatology, Liverpool Hospital, Sydney, Australia.; Faculty of Medicine, University of New South Wales, Sydney, Australia.

Subjects: Dermatitis, Atopic/Dermatitis, Atopic/Dermatitis, Atopic/*drug therapy ; Enzyme Inhibitors/Enzyme Inhibitors/Enzyme Inhibitors/*therapeutic use ; IMP Dehydrogenase/IMP Dehydrogenase/IMP Dehydrogenase/*antagonists & inhibitors

  • Source: The Journal of dermatological treatment [J Dermatolog Treat] 2020 Dec; Vol. 31 (8), pp. 810-814. Date of Electronic Publication: 2019 Aug 01.Publisher: Informa Healthcare Country of Publication: England NLM ID: 8918133 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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