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Academic Journal

High heteroplasmy is associated with low mitochondrial copy number and selection against non-synonymous mutations in the snail Cepaea nemoralis.

Subjects: Snails*/Snails*/Snails*/genetics ; DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/genetics ; Heteroplasmy*/Heteroplasmy*/Heteroplasmy*/genetics

  • Source: BMC genomics [BMC Genomics] 2024 Jun 13; Vol. 25 (1), pp. 596. Date of Electronic Publication: 2024 Jun 13.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Nanobiopsy investigation of the subcellular mtDNA heteroplasmy in human tissues.

  • Authors : Bury A; Wellcome Centre for Mitochondrial Research, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK.; NIHR Biomedical Research Centre, Faculty of Medical Science, Newcastle University, Newcastle, UK.

Subjects: DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/genetics ; Heteroplasmy*/Heteroplasmy*/Heteroplasmy*/genetics ; High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/High-Throughput Nucleotide Sequencing*/methods

  • Source: Scientific reports [Sci Rep] 2024 Jun 14; Vol. 14 (1), pp. 13789. Date of Electronic Publication: 2024 Jun 14.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Single-mitochondrion sequencing uncovers distinct mutational patterns and heteroplasmy landscape in mouse astrocytes and neurons.

  • Authors : Kadam PS; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Yang Z

Subjects: Astrocytes*/Astrocytes*/Astrocytes*/metabolism ; Neurons*/Neurons*/Neurons*/metabolism ; Mutation*

  • Source: BMC biology [BMC Biol] 2024 Jul 29; Vol. 22 (1), pp. 162. Date of Electronic Publication: 2024 Jul 29.Publisher: BioMed Central Country of Publication: England NLM ID: 101190720 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7007

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Academic Journal

Clinical Characteristics of Diabetes in People with Mitochondrial DNA 3243A>G Mutation in Korea.

  • Authors : Rho EH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.; Baek SI

Subjects: DNA, Mitochondrial*/DNA, Mitochondrial*/DNA, Mitochondrial*/genetics ; Mitochondrial Diseases*/Mitochondrial Diseases*/Mitochondrial Diseases*/genetics ; Mitochondrial Diseases*/Mitochondrial Diseases*/Mitochondrial Diseases*/diagnosis Noninsulin-dependent diabetes mellitus with deafness

  • Source: Diabetes & metabolism journal [Diabetes Metab J] 2024 May; Vol. 48 (3), pp. 482-486. Date of Electronic Publication: 2024 Feb 01.Publisher: Korean Diabetes Association Country of Publication: Korea (South) NLM ID: 101556588 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

Mitochondrial DNA somatic mutation burden and heteroplasmy are associated with chronological age, smoking, and HIV infection.

Subjects: Mutation*; Aging/Aging/Aging/*genetics ; DNA, Mitochondrial/DNA, Mitochondrial/DNA, Mitochondrial/*genetics

  • Source: Aging cell [Aging Cell] 2019 Dec; Vol. 18 (6), pp. e13018. Date of Electronic Publication: 2019 Aug 13.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Heteroplasmy concordance between mitochondrial DNA and RNA.

  • Authors : Zhang R; Division of Nutritional Sciences, Cornell University, Ithaca, New York, 14853, USA. .; Regeneron Pharmaceuticals, Inc, Tarrytown, NY, 10591, USA. .

Subjects: Mutation*; Computational Biology/Computational Biology/Computational Biology/*methods ; DNA Mutational Analysis/DNA Mutational Analysis/DNA Mutational Analysis/*methods

  • Source: Scientific reports [Sci Rep] 2019 Sep 10; Vol. 9 (1), pp. 12942. Date of Electronic Publication: 2019 Sep 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Heteroplasmy Detection of Mitochondrial DNA A3243G Mutation Using Quantitative Real-Time PCR Assay Based on TaqMan-MGB Probes.

  • Authors : Rong E; Chinovo Laboratory, Beijing, China.; Wang H

Subjects: DNA, Mitochondrial/DNA, Mitochondrial/DNA, Mitochondrial/*genetics ; Mutation/Mutation/Mutation/*genetics ; Real-Time Polymerase Chain Reaction/Real-Time Polymerase Chain Reaction/Real-Time Polymerase Chain Reaction/*methods

  • Source: BioMed research international [Biomed Res Int] 2018 Nov 13; Vol. 2018, pp. 1286480. Date of Electronic Publication: 2018 Nov 13 (Print Publication: 2018).Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Mitochondrial DNA m.3243A > G heteroplasmy affects multiple aging phenotypes and risk of mortality.

  • Authors : Tranah GJ; California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA. .; Katzman SM

Subjects: Aging/Aging/Aging/*genetics ; DNA, Mitochondrial/DNA, Mitochondrial/DNA, Mitochondrial/*genetics ; Dementia/Dementia/Dementia/*mortality

  • Source: Scientific reports [Sci Rep] 2018 Aug 08; Vol. 8 (1), pp. 11887. Date of Electronic Publication: 2018 Aug 08.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mitochondrial DNA Heteroplasmy and Purifying Selection in the Mammalian Female Germ Line.

  • Authors : Burr SP; MRC Mitochondrial Biology Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Pezet M

Subjects: Mutation* ; Selection, Genetic*; DNA, Mitochondrial/DNA, Mitochondrial/DNA, Mitochondrial/*genetics

  • Source: Development, growth & differentiation [Dev Growth Differ] 2018 Jan; Vol. 60 (1), pp. 21-32. Date of Electronic Publication: 2018 Jan 24.Publisher: Blackwell Publishing on behalf of the Japanese Society of Developmental Biologists Country of Publication: Japan NLM ID: 0356504 Publication Model:

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