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  • 1-10 ل  243 نتائج ل ""CHECKPOINT kinase 1""

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Subject : mutation
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Academic Journal

Profiling genetic mutations in the DNA damage repair genes of oral squamous cell carcinoma patients from Pakistan.

  • Authors : Naeem W; Institute of Basic Medical Sciences, Khyber Medical University, Phase V, Peshawar, 25000, Pakistan.; Nawab F

Subjects: DNA Repair*/DNA Repair*/DNA Repair*/genetics ; Mutation* ; Mouth Neoplasms*/Mouth Neoplasms*/Mouth Neoplasms*/genetics

  • Source: Scientific reports [Sci Rep] 2025 Mar 06; Vol. 15 (1), pp. 7896. Date of Electronic Publication: 2025 Mar 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

Subjects: 0301 basic medicine; Crystallography; Brain

  • Source: Journal of Medicinal Chemistry. 60:8945-8962

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Academic Journal

5-FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53-mutated colon cancer cells

Subjects: 0301 basic medicine; Cell Cycle; Antineoplastic Agents

  • Source: International Journal of Oncology. 46:63-70

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Academic Journal

KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damage.

  • Authors : Gong EY; Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow G61 1BD, U.K.; Smits VAJ

Subjects: DNA Damage* ; Mutation*; Protein Interaction Domains and Motifs/Protein Interaction Domains and Motifs/Protein Interaction Domains and Motifs/*genetics

  • Source: Scientific reports [Sci Rep] 2015 Jun 03; Vol. 5, pp. 10856. Date of Electronic Publication: 2015 Jun 03.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Role of swi7H4 mutant allele of DNA polymerase α in the DNA damage checkpoint response.

  • Authors : Khan S; Molecular and Structural Biology Division, CSIR- Central Drug Research Institute, Jankipuram Extension, Lucknow, India.; Ahmed S

Subjects: Alleles* ; DNA Damage* ; Mutation*

  • Source: PloS one [PLoS One] 2015 Mar 30; Vol. 10 (3), pp. e0124063. Date of Electronic Publication: 2015 Mar 30 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Context Dependence of Checkpoint Kinase 1 as a Therapeutic Target for Pancreatic Cancers Deficient in the BRCA2 Tumor Suppressor

Subjects: BRCA2 Protein; 0301 basic medicine; Tumor Suppressor Proteins

  • Source: Molecular Cancer Therapeutics. 10:670-678

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Academic Journal

Coupling Cellular Localization and Function of Checkpoint Kinase 1 (Chk1) in Checkpoints and Cell Viability

Subjects: Cell Nucleus; Nuclear Export Signals; 0301 basic medicine

  • Source: Journal of Biological Chemistry. 287:25501-25509

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Academic Journal

Checkpoint kinase 1 modulates sensitivity to cisplatin after spindle checkpoint activation in SW620 cells

Subjects: G2 Phase; 0301 basic medicine; Gene Expression Profiling

  • Source: Digital.CSIC. Repositorio Institucional del CSICConsejo Superior de Investigaciones Científicas (CSIC)instname

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Academic Journal

Interaction of checkpoint kinase 1 and the X‐linked inhibitor of apoptosis during mitosis

Subjects: Chk1; Amino Acid Motifs; Mitosis

  • Source: FEBS Letters. 558:57-62

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Academic Journal

Sleep, aging, and lifespan in Drosophila.

  • Authors : Bushey D; Dept of Psychiatry, University of Wisconsin/Madison, Madison, Wisconsin 53719, USA.; Hughes KA

Subjects: Aging/Aging/Aging/*genetics ; Drosophila melanogaster/Drosophila melanogaster/Drosophila melanogaster/*genetics ; Longevity/Longevity/Longevity/*genetics

  • Source: BMC neuroscience [BMC Neurosci] 2010 Apr 29; Vol. 11, pp. 56. Date of Electronic Publication: 2010 Apr 29.Publisher: BioMed Central Country of Publication: England NLM ID: 100966986 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2202

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  • 1-10 ل  243 نتائج ل ""CHECKPOINT kinase 1""