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  • 1-10 ل  261 نتائج ل ""CHECKPOINT kinase 1""

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Subject : mitosis
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Academic Journal

Small-Molecule Mitotic Inhibitors as Anticancer Agents: Discovery, Classification, Mechanisms of Action, and Clinical Trials.

Subjects: *Microtubule-associated protein kinase; *Checkpoint kinase 1; *Antimitotic agents

  • Source: International Journal of Molecular Sciences. Apr2025, Vol. 26 Issue 7, p3279. 36p.

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Academic Journal

Mitotic entry upon Topo II catalytic inhibition is controlled by Chk1 and Plk1.

  • Authors : Arroyo M; Departamento de Biología Experimental, Universidad de Jaén, Spain.; Cañuelo A

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Checkpoint Kinase 1/Checkpoint Kinase 1/Checkpoint Kinase 1/*metabolism ; DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/*metabolism

  • Source: The FEBS journal [FEBS J] 2020 Nov; Vol. 287 (22), pp. 4933-4951. Date of Electronic Publication: 2020 Mar 20.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Sterigmatocystin-induced checkpoint adaptation depends on Chk1 in immortalized human gastric epithelial cells in vitro.

  • Authors : Jiang X; Laboratory of Pathology, Hebei Medical University, No. 361, Zhongshan Eastern Road, Shijiazhuang, Hebei Province, People's Republic of China.; Department of Pathology, Hebei University of Chinese Medicine, Shijiazhuang, Hebei Province, People's Republic of China.

Subjects: DNA Damage*; Carcinogenesis/Carcinogenesis/Carcinogenesis/*chemically induced ; Carcinogens, Environmental/Carcinogens, Environmental/Carcinogens, Environmental/*toxicity

  • Source: Archives of toxicology [Arch Toxicol] 2017 Jan; Vol. 91 (1), pp. 259-270. Date of Electronic Publication: 2016 Feb 25.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Glucocorticoids and checkpoint tyrosine kinase inhibitors stimulate rat pancreatic beta cell proliferation differentially.

  • Authors : Akbib S; Unit Diabetes Pathology and Therapy, Diabetes Research Cluster, Vrije Universiteit Brussel, Brussels, Belgium.; Stichelmans J

Subjects: G1 Phase/G1 Phase/G1 Phase/*drug effects ; Glucocorticoids/Glucocorticoids/Glucocorticoids/*pharmacology ; Insulin-Secreting Cells/Insulin-Secreting Cells/Insulin-Secreting Cells/*metabolism

  • Source: PloS one [PLoS One] 2019 Feb 19; Vol. 14 (2), pp. e0212210. Date of Electronic Publication: 2019 Feb 19 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Checkpoint Kinase 1 Inhibition Enhances Cisplatin Cytotoxicity and Overcomes Cisplatin Resistance in SCLC by Promoting Mitotic Cell Death

Subjects: 0301 basic medicine; Lung Neoplasms; Cell Death

  • Source: Journal of Thoracic Oncology. 14:1032-1045

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Academic Journal

A mitosis-specific and R loop-driven ATR pathway promotes faithful chromosome segregation.

  • Authors : Kabeche L; Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA.; Nguyen HD

Subjects: Centromere/Centromere/Centromere/*enzymology ; Chromosome Segregation/Chromosome Segregation/Chromosome Segregation/*genetics ; Mitosis/Mitosis/Mitosis/*genetics

  • Source: Science (New York, N.Y.) [Science] 2018 Jan 05; Vol. 359 (6371), pp. 108-114. Date of Electronic Publication: 2017 Nov 23.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

DNA damage control: regulation and functions of checkpoint kinase 1

Subjects: DNA Replication; Enzyme Activation; 0301 basic medicine

  • Source: FEBS Journal

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Academic Journal

Checkpoint kinase 1 is activated and promotes cell survival after exposure to sulphur mustard

Subjects: 0303 health sciences; Cell Survival; Mitosis

  • Source: Toxicology Letters. 232:413-421

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Academic Journal

Identification of XAF1 as a novel cell cycle regulator through modulating G2/M checkpoint and interaction with checkpoint kinase 1 in gastrointestinal cancer

Subjects: G2 Phase; 0301 basic medicine; Caspase 3

  • Source: Carcinogenesis. 30:1507-1516

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Academic Journal

The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis

Subjects: 0301 basic medicine; Mitosis; Epithelial Cells

  • Source: Proceedings of the National Academy of Sciences. 106:5159-5164

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  • 1-10 ل  261 نتائج ل ""CHECKPOINT kinase 1""