نتائج البحث

ONC212, alone or in synergistic conjunction with Navitoclax (ABT-263), promotes cancer cell apoptosis via unconventional mitochondrial-independent caspase-3 activation.

• Authors : Basu V; Department of Biotechnology, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029, India.; Shabnam

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Mitochondria*/Mitochondria*/Mitochondria*/drug effects ; Mitochondria*/Mitochondria*/Mitochondria*/metabolism

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 13; Vol. 22 (1), pp. 441. Date of Electronic Publication: 2024 Sep 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Insulin reduces endoplasmic reticulum stress-induced apoptosis by decreasing mitochondrial hyperpolarization and caspase-12 in INS-1 pancreatic β-cells.

• Authors : Murata N; Department of Applied Biological Chemistry, Graduate School of Agriculture, Osaka Metropolitan University, Sakai, Osaka, Japan.; Nishimura K

Subjects: Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/metabolism ; Insulin-Secreting Cells*/Insulin-Secreting Cells*/Insulin-Secreting Cells*/drug effects ; Apoptosis*/Apoptosis*/Apoptosis*/drug effects

• Source: Physiological reports [Physiol Rep] 2024 Jun; Vol. 12 (12), pp. e16106.Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM

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PPARγ regulates osteoarthritis chondrocytes apoptosis through caspase-3 dependent mitochondrial pathway.

• Authors : Yuan H; Graduate School of Bengbu Medical College, Bengbu, China.; Department of Orthopedics, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, China.

Subjects: Apoptosis* ; Caspase 3*/Caspase 3*/Caspase 3*/metabolism ; Chondrocytes*/Chondrocytes*/Chondrocytes*/metabolism

• Source: Scientific reports [Sci Rep] 2024 May 16; Vol. 14 (1), pp. 11237. Date of Electronic Publication: 2024 May 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Organophosphorus Flame Retardant TPP-Induced Human Corneal Epithelial Cell Apoptosis through Caspase-Dependent Mitochondrial Pathway.

• Authors : Chen C; Yunnan Province Innovative Research Team of Environmental Pollution, Food Safety and Human Health, Institute of Environmental Remediation and Human Health, School of Ecology and Environment, Southwest Forestry University, Kunming 650224, China.; Cui D

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Flame Retardants*/Flame Retardants*/Flame Retardants*/toxicity ; Flame Retardants*/Flame Retardants*/Flame Retardants*/pharmacology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 09; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Empagliflozin Prevent High-Glucose Stimulation Inducing Apoptosis and Mitochondria Fragmentation in H9C2 Cells through the Calcium-Dependent Activation Extracellular Signal-Regulated Kinase 1/2 Pathway.

• Authors : Chen YL; Division of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan.; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan 333, Taiwan.

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Benzhydryl Compounds*/Benzhydryl Compounds*/Benzhydryl Compounds*/pharmacology ; Glucosides*/Glucosides*/Glucosides*/pharmacology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 28; Vol. 25 (15). Date of Electronic Publication: 2024 Jul 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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TPOL triggers apoptosis with mitochondrial injury through activating a ROS-dependent p53/p21/p27/Rb/Bax/Cyto C/caspase-mediated signaling.

• Authors : CHENG Zongwei¹; ZENG Boning¹; XING Feiyue¹

• Source: Chinese Journal of Pathophysiology. Aug2024, Vol. 40 Issue 8, p1488-1496. 9p.

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Caspase inhibition rescues F1Fo ATP synthase dysfunction-mediated dendritic spine elimination.

• Authors : Chen H; Department of Biological Sciences, The University of Texas at Dallas, 800 west Campbell Rd, Richardson, TX, 75080, USA.; Tian J

Subjects: Dendritic Spines/Dendritic Spines/Dendritic Spines/*metabolism ; Mitochondria/Mitochondria/Mitochondria/*metabolism ; Mitochondrial Proton-Translocating ATPases/Mitochondrial Proton-Translocating ATPases/Mitochondrial Proton-Translocating ATPases/*metabolism

• Source: Scientific reports [Sci Rep] 2020 Oct 16; Vol. 10 (1), pp. 17589. Date of Electronic Publication: 2020 Oct 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Rosiglitazone in the thawing medium improves mitochondrial function in stallion spermatozoa through regulating Akt phosphorylation and reduction of caspase 3.

• Authors : Ortiz-Rodriguez JM; Laboratory of Equine Reproduction and Equine Spermatology, Veterinary Teaching Hospital, University of Extremadura, Cáceres, Spain.; Balao da Silva C

Subjects: Hypoglycemic Agents/Hypoglycemic Agents/Hypoglycemic Agents/*administration & dosage ; Mitochondria/Mitochondria/Mitochondria/*drug effects ; Rosiglitazone/Rosiglitazone/Rosiglitazone/*administration & dosage

• Source: PloS one [PLoS One] 2019 Jul 05; Vol. 14 (7), pp. e0211994. Date of Electronic Publication: 2019 Jul 05 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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New Alkoxy- Analogues of Epoxyeicosatrienoic Acids Attenuate Cisplatin Nephrotoxicity In Vitro via Reduction of Mitochondrial Dysfunction, Oxidative Stress, Mitogen-Activated Protein Kinase Signaling, and Caspase Activation

• Authors : Singh, Nalin; Vik, Anders; Lybrand, Daniel B

Subjects: Medicinal and Biomolecular Chemistry; Organic Chemistry; Chemical Sciences

• Source: Chemical Research in Toxicology. 34(12)

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Aviculin Isolated from Lespedeza cuneata Induce Apoptosis in Breast Cancer Cells through Mitochondria-Mediated Caspase Activation Pathway.

• Authors : Lee D; College of Korean Medicine, Gachon University, Seongnam 13120, Korea.; Lee YH

Subjects: Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*pathology

• Source: Molecules (Basel, Switzerland) [Molecules] 2020 Apr 08; Vol. 25 (7). Date of Electronic Publication: 2020 Apr 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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