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Targeting undruggable phosphatase overcomes trastuzumab resistance by inhibiting multi-oncogenic kinases

• Authors : Wang, Lu; Lin, Yusheng; Yao, Zhimeng

Subjects: Trastuzumab/pharmacology; Humans; Drug Resistance

• Source: Wang , L , Lin , Y , Yao , Z , Babu , N , Lin , W , Chen , C , Du , L , Cai , S , Pan , Y , Xiong , X , Ye , Q , Ren , H , Zhang , D , Chen , Y , Yeung , S-C J , Bremer , E & Zhang , H 2024 , '

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A SRC-slug-TGFβ2 signaling axis drives poor outcomes in triple-negative breast cancers

• Authors : Angel, Charlotte Zoe; Beattie, Shannon; Hanif, Ezanee Azlina Mohamad

Subjects: Triple Negative Breast Neoplasms/genetics; Humans; Signal Transduction/drug effects

• Source: Angel , C Z , Beattie , S , Hanif , E A M , Ryan , M P , Guerra Liberal , F D C , Zhang , S-D , Monteith , S , Buckley , N E , Parker , E , Haynes , S , McIntyre , A J , Haddock , P , Sharifova , M ,

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Fibrotic response to anti-CSF-1R therapy potentiates glioblastoma recurrence.

• Authors : Watson, S.S.; Zomer, A.; Fournier, N.

Subjects: Glioblastoma/drug therapy; Glioblastoma/pathology; Animals

• Source: Cancer cell, vol. 42, no. 9, pp. 1507-1527.e11

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Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways

• Authors : Kurmasheva, Naziia; Said, Aida; Wong, Boaz

Subjects: Animals; Humans; Oncolytic Virotherapy/methods

• Source: Kurmasheva , N , Said , A , Wong , B , Kinderman , P , Han , X , Rahimic , A H F , Kress , A , Carter-Timofte , M E , Holm , E , van der Horst , D , Kollmann , C F , Liu , Z , Wang , C , Hoang , H-D ,

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Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells

• Authors : Evan R Abt; Thuc M Le; Amanda M Dann

Subjects: Adenocarcinoma / metabolism; Adenocarcinoma / pathology; Animals

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Glucocorticoids dexamethasone and prednisolone suppress fibroblast growth factor 23 (FGF23)

• Authors : Feger, Martina; Ewendt, Franz; Strotmann, Jörg

Subjects: Cell Line; Tumor [MeSH]; Mice

• Source: http://lobid.org/resources/99370678534106441#!, 99(5):699-711.

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Pharmacological Inhibition of Sonic Hedgehog Signaling Suppresses Tumor Development in a Murine Model of Intrahepatic Cholangiocarcinoma

• Authors : Kyungjoo Cho; Hyuk Moon; Sang Hyun Seo

Subjects: Anilides / administration & dosage; Anilides / pharmacology; Animals

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The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development.

• Authors : Tenenbaum, M.; Plaisance, V.; Boutry, R.

Subjects: Animals; Cell Proliferation/drug effects; Cyclin D1/genetics

• Source: Cellular and molecular life sciences, vol. 78, no. 1, pp. 287-298

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Wdr1 and cofilin are necessary mediators of immune-cell-specific apoptosis triggered by Tecfidera.

• Authors : Poganik, J.R.; Huang, K.T.; Parvez, S.

Subjects: Actin Depolymerizing Factors/metabolism; Animals; Genetically Modified

• Source: Nature communications, vol. 12, no. 1, pp. 5736

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Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma

• Authors : Raggi, Chiara; Taddei, Maria Letizia; Sacco, Elena

Subjects: Animals; Bile Duct Neoplasms/drug therapy; Carcinogenesis/drug effects

• Source: Raggi , C , Taddei , M L , Sacco , E , Navari , N , Correnti , M , Piombanti , B , Pastore , M , Campani , C , Pranzini , E , Iorio , J , Lori , G , Lottini , T , Peano , C , Cibella , J , Lewinska ,

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