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ATAXIN-2 intermediate-length polyglutamine expansions elicit ALS-associated metabolic and immune phenotypes

• Authors : Vieira de Sá, Renata; Sudria-Lopez, Emma; Cañizares Luna, Marta ...

Subjects: Amyotrophic Lateral Sclerosis/genetics; Animals; Ataxin-2/genetics

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Development of a genetically encoded sensor for probing endogenous nociceptin opioid peptide release

• Authors : Zhou, Xuehan; Stine, Carrie; Prada, Patricia Oliveira

Subjects: info:eu-repo/classification/ddc/612; Animals; Opioid Peptides / metabolism

• Source: ISSN: 2041-1723 ; Nature communications, vol. 15, no. 1 (2024) 5353.

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Co-delivery of PD-L1- and EGFR-targeting siRNAs by synthetic PEG 12-KL4 peptide to the lungs as potential strategy against non-small cell lung cancer.

• Authors : Man, Rico C H; Qiu, Yingshan; Leung, Susan W S

Subjects: Animals; Mice; Carcinoma

• Source: Man , R C H , Qiu , Y , Leung , S W S , Fruhwirth , G O & Lam , J K W 2024 , ' Co-delivery of PD-L1- and EGFR-targeting siRNAs by synthetic PEG 12-KL4 peptide to the lungs as potential strategy

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A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls

• Authors : Pesämaa, Ida; Müller, Stephan A.; Robinson, Sophie

Subjects: info:eu-repo/classification/ddc/570; Humans; MiceDE

• Source: Molecular neurodegeneration 18(1), 70 (2023). doi:10.1186/s13024-023-00657-w

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New Highly Selective BACE1 Inhibitors and Their Effects on Dendritic Spine Density In Vivo.

• Authors : Pratsch, Katrin; Unemura, Chie; Ito, Mana

Subjects: info:eu-repo/classification/ddc/540; Animals; MiceDE

• Source: International journal of molecular sciences 24(15), 12283 (2023). doi:10.3390/ijms241512283 special issue: "Advance on the Research of Alzheimer's Disease"

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A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease.

• Authors : Boeddrich, Annett; Haenig, Christian; Sporbert, Anje

Subjects: info:eu-repo/classification/ddc/610; Mice; HumansDE

• Source: Genome medicine 15(1), 50 (2023). doi:10.1186/s13073-023-01206-2

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Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.

• Authors : Depp, Constanze; Sun, Ting; Ruhwedel, Torben

Subjects: info:eu-repo/classification/ddc/500; Alzheimer Disease: metabolism; MiceDE

• Source: Nature 618(7964), 349 - 357 (2023). doi:10.1038/s41586-023-06120-6

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Jacob-induced transcriptional inactivation of CREB promotes Aβ-induced synapse loss in Alzheimer's disease.

• Authors : Grochowska, Katarzyna M; Gomes, Guilherme M; Samer, Sebastian

Subjects: info:eu-repo/classification/ddc/570; Animals; MiceDE

• Source: The EMBO journal 42(4), e112453 (2023). doi:10.15252/embj.2022112453

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Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.

• Authors : Stroo, Esther; Janssen, Leen; Becker, Lore

Subjects: info:eu-repo/classification/ddc/570; Brain: embryology; MiceDE

• Source: Life science alliance 6(7), e202201730 (2023). doi:10.26508/lsa.202201730

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[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data.

• Authors : Ballweg, Anna; Klaus, Carolin; Bernhardt, Maximilian Alexander

Subjects: info:eu-repo/classification/ddc/610; Humans; MiceDE

• Source: Journal of neuroinflammation 20(1), 68 (2023). doi:10.1186/s12974-023-02749-2

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