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Targeting undruggable phosphatase overcomes trastuzumab resistance by inhibiting multi-oncogenic kinases

• Authors : Wang, Lu; Lin, Yusheng; Yao, Zhimeng

Subjects: Trastuzumab/pharmacology; Humans; Drug Resistance

• Source: Wang , L , Lin , Y , Yao , Z , Babu , N , Lin , W , Chen , C , Du , L , Cai , S , Pan , Y , Xiong , X , Ye , Q , Ren , H , Zhang , D , Chen , Y , Yeung , S-C J , Bremer , E & Zhang , H 2024 , '

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H2AX promotes replication fork degradation and chemosensitivity in BRCA-deficient tumours

• Authors : Dibitetto, Diego; Liptay, Martin; Vivalda, Francesca

Subjects: info:eu-repo/classification/ddc/616.07; info:eu-repo/classification/ddc/616; info:eu-repo/classification/ddc/618

• Source: ISSN: 2041-1723 ; Nature communications, vol. 15, no. 1 (2024) 4430.

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Cancer-associated fibroblasts induce an aggressive phenotypic shift in non-malignant breast epithelial cells via interleukin-8 and S100A8

• Authors : Hyesol Lim; Minsoo Koh; Hao Jin

Subjects: Animals; Breast Neoplasms / drug therapy; Breast Neoplasms / genetics

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Landscapes of cellular phenotypic diversity in breast cancer xenografts and their impact on drug response.

• Authors : Georgopoulou, D.; Callari, M.; Rueda, O.M. ...

Subjects: Animals; Benzamides/pharmacology; Breast Neoplasms/drug therapy

• Source: Nature communications, vol. 12, no. 1, pp. 1998

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B55α/PP2A Limits Endothelial Cell Apoptosis During Vascular Remodeling:A Complementary Approach To Disrupt Pathological Vessels?

• Authors : Ehling, Manuel; Celus, Ward; Martín-Pérez, Rosa

Subjects: Angiogenesis Inhibitors/pharmacology; Animals; Apoptosis

• Source: Ehling , M , Celus , W , Martín-Pérez , R , Alba-Rovira , R , Willox , S , Ponti , D , Cid , M C , Jones , E A V , Di Conza , G & Mazzone , M 2020 , ' B55α/PP2A Limits Endothelial Cell Apoptosis

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Establishment of Chemosensitivity Tests in Triple-Negative and BRCA-mutated Breast Cancer Patient-Derived Xenograft Models

• Authors : Hyung Seok Park; Jeong Dong Lee; Jee Ye Kim

Subjects: Animals; Antineoplastic Agents / therapeutic use; BRCA1 Protein / genetics

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Type I interferon/IRF7 axis instigates chemotherapy-induced immunological dormancy in breast cancer.

• Authors : Lan, Q.; Peyvandi, S.; Duffey, N.

Subjects: Animals; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Biomarkers

• Source: Oncogene, vol. 38, no. 15, pp. 2814-2829

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Towards the first targeted therapy for triple-negative breast cancer: Repositioning of clofazimine as a chemotherapy-compatible selective Wnt pathway inhibitor.

• Authors : Ahmed, K.; Koval, A.; Xu, J.

Subjects: Animals; Antineoplastic Combined Chemotherapy Protocols/administration & dosage; Antineoplastic Combined Chemotherapy Protocols/therapeutic use

• Source: Cancer letters, vol. 449, pp. 45-55

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Glutamine to proline conversion is associated with response to glutaminase inhibition in breast cancer

• Authors : Grinde, Maria T; Hilmarsdóttir, Bylgja; Tunset, Hanna Maja ...

Subjects: Náttúrufræðingar; Animals; Biomarkers

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Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer

• Authors : Maisel, Sabrina A; Broka, Derrick; Atwell, Benjamin

Subjects: EGFR; EJ1; Glioblastoma

• Source: Translational Neuroscience

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