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  • 1-10 ل  64 نتائج ل ""Myeloid Cell Leukemia Sequence 1 Protein""

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Subject : membrane proteins
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Academic Journal

Obatoclax is a direct and potent antagonist of membrane-restricted Mcl-1 and is synthetic lethal with treatment that induces Bim.

  • Authors : Nguyen M; Department of Biochemistry, McGill University, Montreal, Québec, Canada. .; Cencic R

Subjects: Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism ; Lymphoma/Lymphoma/Lymphoma/*drug therapy ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

  • Source: BMC cancer [BMC Cancer] 2015 Aug 01; Vol. 15, pp. 568. Date of Electronic Publication: 2015 Aug 01.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Lipoic acid decreases Mcl-1, Bcl-xL and up regulates Bim on ovarian carcinoma cells leading to cell death.

  • Authors : Kafara P; INSERM, U 1199, Unité BioTICLA, Caen, F-14032, France. .; Normandie Université France, Caen, France. .

Subjects: Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*biosynthesis ; Carcinoma/Carcinoma/Carcinoma/*drug therapy ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*biosynthesis

  • Source: Journal of ovarian research [J Ovarian Res] 2015 Jun 12; Vol. 8, pp. 36. Date of Electronic Publication: 2015 Jun 12.Publisher: BioMed Central Country of Publication: England NLM ID: 101474849 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-2215

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Academic Journal

Ectopic overexpression of LAPTM5 results in lysosomal targeting and induces Mcl-1 down-regulation, Bak activation, and mitochondria-dependent apoptosis in human HeLa cells.

  • Authors : Jun DY; Laboratory of Immunobiology, School of Life Sciences and Biotechnology, College of Natural Sciences, Kyungpook National University, Daegu, Korea.; Institute of Life Science and Biotechnology, Kyungpook National University, Daegu, Korea.

Subjects: Apoptosis/Apoptosis/Apoptosis/*physiology ; Lysosomes/Lysosomes/Lysosomes/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

  • Source: PloS one [PLoS One] 2017 May 02; Vol. 12 (5), pp. e0176544. Date of Electronic Publication: 2017 May 02 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

BH3-only protein BIM mediates heat shock-induced apoptosis.

  • Authors : Mahajan IM; The University of Texas MD Anderson Cancer Center, Science Park, Department of Molecular Carcinogenesis, Smithville, Texas, United States of America ; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, Austin, Texas, United States of America.

Subjects: Hot Temperature*; Apoptosis/Apoptosis/Apoptosis/*physiology ; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism

  • Source: PloS one [PLoS One] 2014 Jan 10; Vol. 9 (1), pp. e84388. Date of Electronic Publication: 2014 Jan 10 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Trichonomas vaginalis metalloproteinase induces apoptosis of SiHa cells through disrupting the Mcl-1/Bim and Bcl-xL/Bim complexes.

  • Authors : Quan JH; Department of Gastroenterology, The Affiliated Hospital of Guangdong Medical College, Zhanjiang, Guangdong, China.; Kang BH

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

  • Source: PloS one [PLoS One] 2014 Oct 24; Vol. 9 (10), pp. e110659. Date of Electronic Publication: 2014 Oct 24 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

BikDDA, a mutant of Bik with longer half-life expression protein, can be a novel therapeutic gene for triple-negative breast cancer.

  • Authors : Jiao S; Department of Breast Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, China; Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China

Subjects: Molecular Targeted Therapy*; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*genetics ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*genetics

  • Source: PloS one [PLoS One] 2014 Mar 17; Vol. 9 (3), pp. e92172. Date of Electronic Publication: 2014 Mar 17 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

TRIM proteins as trim tabs for the homoeostasis.

  • Authors : Horie-Inoue K; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, 1397-1 Yamane, Hidaka, Saitama 350-1371, Japan.

Subjects: Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*metabolism ; Homeostasis/Homeostasis/Homeostasis/*physiology ; Membrane Proteins/Membrane Proteins/Membrane Proteins/*metabolism

  • Source: Journal of biochemistry [J Biochem] 2013 Oct; Vol. 154 (4), pp. 309-12. Date of Electronic Publication: 2013 Aug 21.Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes apoptosis resistance in leukaemia.

Subjects: Apoptosis/Apoptosis/Apoptosis/*genetics ; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism

  • Source: Cell death and differentiation [Cell Death Differ] 2013 Sep; Vol. 20 (9), pp. 1268-78. Date of Electronic Publication: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Persistent hepatitis C virus (HCV) infection impairs HCV-specific cytotoxic T cell reactivity through Mcl-1/Bim imbalance due to CD127 down-regulation.

  • Authors : Larrubia JR; Translational Hepatology Unit, Guadalajara University Hospital, University of Alcalá, Guadalajara, Spain. ; Lokhande MU

Subjects: Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism ; Hepacivirus/Hepacivirus/Hepacivirus/*immunology ; Hepatitis C, Chronic/Hepatitis C, Chronic/Hepatitis C, Chronic/*immunology

  • Source: Journal of viral hepatitis [J Viral Hepat] 2013 Feb; Vol. 20 (2), pp. 85-94. Date of Electronic Publication: 2012 May 03.Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 9435672 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.

  • Authors : Miller AV; Department of Oral and Craniofacial Molecular Biology, School of Dentistry, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, USA.; Hicks MA

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/Apoptosis Regulatory Proteins/*metabolism

  • Source: PloS one [PLoS One] 2013; Vol. 8 (4), pp. e60685. Date of Electronic Publication: 2013 Apr 05.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 ل  64 نتائج ل ""Myeloid Cell Leukemia Sequence 1 Protein""