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  • 1-10 ل  3,815 نتائج ل ""mTORC1""

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Subject : mechanistic target of rapamycin complex 1
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Academic Journal

Nuclear mTORC1 Live-Cell Sensor nTORSEL Reports Differential Nuclear mTORC1 Activity in Cell Lines.

  • Authors : Wang Y; School of Medicine, Shenzhen Campus of Sun Yat-Sen University, Sun Yat-Sen University, Shenzhen 518107, China.; Li C

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Cell Nucleus*/Cell Nucleus*/Cell Nucleus*/metabolism; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 12; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A Novel 14mer Peptide Inhibits Autophagic Flux via Selective Activation of the mTORC1 Signalling Pathway: Implications for Alzheimer's Disease.

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 29; Vol. 25 (23). Date of Electronic Publication: 2024 Nov 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

EYA3 promotes the tumorigenesis of gastric cancer through activation of the mTORC1 signaling pathway and inhibition of autophagy.

  • Authors : Xu Z; Department of Oncology, Nantong Haimen People's Hospital, Nantong, 226199, China.; Liu J

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Nov 16; Vol. 14 (1), pp. 28355. Date of Electronic Publication: 2024 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

TRIM35 triggers cardiac remodeling by regulating SLC7A5-mediated amino acid transport and mTORC1 activation in fibroblasts.

  • Authors : Yang B; Department of Cardiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.; Wang Z

Subjects: Fibroblasts*/Fibroblasts*/Fibroblasts*/metabolism ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Mice, Knockout*

  • Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Sep 20; Vol. 22 (1), pp. 444. Date of Electronic Publication: 2024 Sep 20.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Academic Journal

mTORC1 pathway activity biases cell fate choice.

  • Authors : Wang Y; Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.; Papayova M

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Dictyostelium*/Dictyostelium*/Dictyostelium*/metabolism ; Dictyostelium*/Dictyostelium*/Dictyostelium*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Sep 06; Vol. 14 (1), pp. 20832. Date of Electronic Publication: 2024 Sep 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Lysosomal TBK1 responds to amino acid availability to relieve Rab7-dependent mTORC1 inhibition.

  • Authors : Talaia G; Department of Cell Biology, Yale University School of Medicine, New Haven, CT, 06510, USA.; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 06510, USA.

Subjects: Amino Acids*/Amino Acids*/Amino Acids*/metabolism ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism

  • Source: The EMBO journal [EMBO J] 2024 Sep; Vol. 43 (18), pp. 3948-3967. Date of Electronic Publication: 2024 Aug 05.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

PP2Ac Regulates Autophagy via Mediating mTORC1 and ULK1 During Osteoclastogenesis in the Subchondral Bone of Osteoarthritis.

  • Authors : Zhang H; Department of Orthopedics Surgery, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China.; Department of Orthopaedic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/genetics ; Autophagy-Related Protein-1 Homolog*/Autophagy-Related Protein-1 Homolog*/Autophagy-Related Protein-1 Homolog*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Sep; Vol. 11 (36), pp. e2404080. Date of Electronic Publication: 2024 Jul 23.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Starvation-induced metabolic rewiring affects mTORC1 composition in vivo.

  • Authors : Kaade E; Institute for Biochemistry and Molecular Biology, Medical Faculty, Rheinische Friedrich-Wilhelms-University of Bonn, 53115, Bonn, Germany.; Mausbach S

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Starvation*/Starvation*/Starvation*/metabolism

  • Source: Scientific reports [Sci Rep] 2024 Nov 16; Vol. 14 (1), pp. 28296. Date of Electronic Publication: 2024 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Acidity suppresses CD8 + T-cell function by perturbing IL-2, mTORC1, and c-Myc signaling.

  • Authors : Vuillefroy de Silly R; Ludwig Institute for Cancer Research, University of Lausanne and Department of Oncology, Lausanne University Hospital (CHUV), Lausanne, Switzerland. .; Pericou L

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/immunology ; CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/CD8-Positive T-Lymphocytes*/metabolism

  • Source: The EMBO journal [EMBO J] 2024 Nov; Vol. 43 (21), pp. 4922-4953. Date of Electronic Publication: 2024 Sep 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

The Combined Inhibition of SREBP and mTORC1 Signaling Synergistically Inhibits B-Cell Lymphoma.

  • Authors : Zhu Z; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Jiang W

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/antagonists & inhibitors ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

  • Source: Cancer medicine [Cancer Med] 2024 Nov; Vol. 13 (21), pp. e70342.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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  • 1-10 ل  3,815 نتائج ل ""mTORC1""