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Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture.

• Authors : Badolo, Lassina¹ (AUTHOR) ; Jensen, Bente¹ (AUTHOR); Säll, Carolina¹ (AUTHOR)

• Source: Xenobiotica. Feb2015, Vol. 45 Issue 2, p177-187. 11p.

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Potent inhibition of CYP1A2 by Frutinone A, an active ingredient of the broad spectrum antimicrobial herbal extract from P. fruticosa.

• Authors : Thelingwani, Roslyn S.^1,2 (AUTHOR); Dhansay, Kariema³ (AUTHOR); Smith, Peter³ (AUTHOR)

• Source: Xenobiotica. Oct2012, Vol. 42 Issue 10, p989-1000. 12p.

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The Induction of CYP1A2, CYP2D6 and CYP3A4 by Six Trade Herbal Products in Cultured Primary Human Hepatocytes.

• Authors : Hellum, Bent H.¹ ; Zhuohan Hu²; Nilsen, Odd Georg¹

• Source: Basic & Clinical Pharmacology & Toxicology. Jan2007, Vol. 100 Issue 1, p23-30. 8p. 2 Charts, 5 Graphs.

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Species difference in the induction of hepatic CYP1A subfamily enzymes, especially CYP1A2, by 2-methoxy-4-nitroaniline among rats, mice, and guinea pigs.

• Authors : Souma, Shinji¹; Sekimoto, Masashi¹; Degawa, Masakuni¹

Subjects: *MESSENGER RNA; *DRUG metabolism; *LIVER cells

• Source: Archives of Toxicology. Nov2006, Vol. 80 Issue 11, p739-747. 9p.

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Ochratoxin A induces CYP3A4, 2B6, 3A5, 2C9, 1A1, and CYP1A2 gene expression in primary cultured human hepatocytes: a possible activation of nuclear receptors.

• Authors : Ayed-Boussema, Imen¹ (AUTHOR); Pascussi, Jean Marc^2,3 (AUTHOR); Zaied, Chiraz¹ (AUTHOR)

• Source: Drug & Chemical Toxicology. Jan2012, Vol. 35 Issue 1, p71-80. 10p.

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CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes.

• Authors : Liu, H.-X.^1,2 (AUTHOR); Hu, Y.^1,2 (AUTHOR); Liu, Y.¹ (AUTHOR)

• Source: Xenobiotica. Sep2009, Vol. 39 Issue 9, p672-679. 8p. 1 Diagram, 6 Graphs.

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In Vitro Evaluation of the Potential for Drug Interactions by Salidroside.

• Authors : Kasprzyk, Philip G.¹ ; Tremaine, Larry² ; Fahmi, Odette A.³

Subjects: *IN vitro studies; *CYTOCHROME P-450; *BIOMEDICAL engineering

• Source: Nutrients. Sep2023, Vol. 15 Issue 17, p3723. 14p.

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Effect of buagafuran on liver microsomal cytochrome P450 in rats.

• Authors : Li, En¹ (AUTHOR); Hu, Jin-Ping¹ (AUTHOR); Wang, Bao-Lian¹ (AUTHOR)

• Source: Journal of Asian Natural Products Research. May2010, Vol. 12 Issue 5, p371-381. 11p. 1 Diagram, 4 Charts, 5 Graphs.

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Metabolism of ropinirole is mediated by several canine CYP enzymes.

• Authors : Tervahauta, Tuomas¹ (AUTHOR); Uutela, Päivi¹ (AUTHOR); Koskinen, Mikko¹ (AUTHOR)

• Source: Veterinary Medicine & Science. Jul2023, Vol. 9 Issue 4, p1584-1591. 8p.

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In vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes.

• Authors : Lee, H. S.¹ (AUTHOR) ; Ji, H. Y.¹ (AUTHOR); Park, E. J.¹ (AUTHOR)

• Source: Xenobiotica. Aug2007, Vol. 37 Issue 8, p803-817. 15p. 1 Diagram, 4 Charts, 7 Graphs.

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