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Fragment-based approach to drug lead discovery: overview and advances in various techniques.

• Authors : Fattori D; Chemistry Department, Menarini Ricerche, Pomezia, Rome, Italy.; Squarcia A

Subjects: Drug Design*; Peptide Fragments/Peptide Fragments/Peptide Fragments/*pharmacology ; Pharmacology/Pharmacology/Pharmacology/*trends

• Source: Drugs in R&D [Drugs R D] 2008; Vol. 9 (4), pp. 217-27.Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 100883647 Publication Model: Print Cited Medium: Print ISSN:

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Investigation of Elemental Mass Spectrometry in Pharmacology for Peptide Quantitation at Femtomolar Levels.

• Authors : Cordeau E; Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, Place Eugène Bataillon, 34095 Montpellier cedex 5, France.; Arnaudguilhem C

Subjects: Mass Spectrometry/Mass Spectrometry/Mass Spectrometry/*methods ; Mass Spectrometry/Mass Spectrometry/Mass Spectrometry/*standards ; Peptides/Peptides/Peptides/*chemistry

• Source: PloS one [PLoS One] 2016 Jun 23; Vol. 11 (6), pp. e0157943. Date of Electronic Publication: 2016 Jun 23 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Signal Sequence-Dependent Orientation of Signal Peptide Fragments to Exosomes

• Authors : Kenji Ono; Mikio Niwa; Hiromi Suzuki

Subjects: Placenta; Organic Chemistry; General Medicine

• Source: International Journal of Molecular Sciences; Volume 23; Issue 6; Pages: 3137

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Peptide fragments of bradykinin show unexpected biological activity not mediated by B 1 or B 2 receptors

• Authors : Igor Maciel Souza‐Silva; Cristiane Amorim Paula; Lucas Bolais‐Ramos

Subjects: Pharmacology

• Source: British Journal of Pharmacology. 179:3061-3077

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Peptide fragments of Hsp70 modulate its chaperone activity and sensitize tumor cells to anti-cancer drugs

• Authors : Vladimir F. Lazarev; Pavel I. Semenyuk; Irina V. Guzhova

Subjects: 0301 basic medicine; Drug; Protein Folding

• Source: FEBS Letters. 591:4074-4082

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Absolute Quantitation of Tryptophan-Containing Peptides and Amyloid β‑Peptide Fragments by Coulometric Mass Spectrometry

• Authors : Yongling Ai (9546571); Pengyi Zhao (8847701); Praneeth Ivan Joel FNU (10942183)

Subjects: Biophysics; Biochemistry; Physiology

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Symbiotic NCR Peptide Fragments Affect the Viability, Morphology and Biofilm Formation of Candida Species

• Authors : Bettina Szerencsés; Csaba Vágvölgyi; Ilona Pfeiffer

Subjects: 0301 basic medicine; Pore Forming Cytotoxic Proteins; Antifungal Agents

• Source: International Journal of Molecular SciencesVolume 22Issue 7International Journal of Molecular Sciences, Vol 22, Iss 3666, p 3666 (2021)

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Association of β-amyloid peptide fragments with neuronal nitric oxide synthase: Implications in the etiology of Alzheimers disease

• Authors : Nosiphiwe P. Ngqwala; Eden Padayachee; Chris G. Whiteley

Subjects: Dimer; Peptide; Nitric Oxide Synthase Type I

• Source: Journal of Enzyme Inhibition and Medicinal Chemistry. 27:356-364

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Further Characterization of Hemopressin Peptide Fragments in the Opioid and Cannabinoid Systems

• Authors : Csaba Tömböly; Eszter Szlavicz; Zsuzsanna Helyes

Subjects: AM251; medicine.drug_class; medicine.medical_treatment

• Source: Anesthesia and analgesia. 121(6)

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Mechanistic Studies of the Process of Amyloid Fibrils Formation by the Use of Peptide Fragments and Analogues: Implications for the Design of Fibrillization Inhibitors

• Authors : Ehud Gazit

Subjects: Models, Molecular; Protein Folding; Amyloid

• Source: Current Medicinal Chemistry. 9:1725-1735

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