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The role of miR-155-5p in inflammation and mechanical loading during intervertebral disc degeneration.

• Authors : Cazzanelli P; Department of Biomedical Engineering, Rochester Institute of Technology, Rochester, NY, USA.; Lamoca M

Subjects: MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics ; MicroRNAs*/MicroRNAs*/MicroRNAs*/metabolism ; Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/Intervertebral Disc Degeneration*/genetics

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 Aug 28; Vol. 22 (1), pp. 419. Date of Electronic Publication: 2024 Aug 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Dynamics of CD44 + bovine nucleus pulposus cells with inflammation.

• Authors : Ferreira JR; I3S-Instituto de Investigação e Inovação em Saúde, Universidade Do Porto, Porto, Portugal.; INEB-Instituto de Engenharia Biomédica, Universidade Do Porto, Porto, Portugal.

Subjects: Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/metabolism ; Nucleus Pulposus*/Nucleus Pulposus*/Nucleus Pulposus*/pathology ; Hyaluronan Receptors*/Hyaluronan Receptors*/Hyaluronan Receptors*/metabolism

• Source: Scientific reports [Sci Rep] 2024 Apr 21; Vol. 14 (1), pp. 9156. Date of Electronic Publication: 2024 Apr 21.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Human umbilical cord-derived mesenchymal stem cells and their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in a rat intervertebral disc degeneration model.

• Authors : Ekram S; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan.; Khalid S

Subjects: Chondrogenesis* ; Regeneration*; Inflammation/Inflammation/Inflammation/*prevention & control

• Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2021 Aug; Vol. 476 (8), pp. 3191-3205. Date of Electronic Publication: 2021 Apr 17.Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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线粒体自噬与椎间盘退变.

• Authors : 潘世鸿¹; 刘瑞端²

• Source: Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu. 12/28/2024, Vol. 28 Issue 36, p5872-5876. 5p.

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Ultra-purified alginate gel implantation decreases inflammatory cytokine levels, prevents intervertebral disc degeneration, and reduces acute pain after discectomy.

• Authors : Ura K; Department of Orthopedic Surgery, Faculty of Medicine and Graduate of Medicine, Hokkaido University, N15W7, Sapporo, Hokkaido, 060-8638, Japan.; Yamada K

Subjects: Acute Pain/Acute Pain/Acute Pain/*prevention & control ; Alginates/Alginates/Alginates/*administration & dosage ; Cytokines/Cytokines/Cytokines/*metabolism

• Source: Scientific reports [Sci Rep] 2021 Jan 12; Vol. 11 (1), pp. 638. Date of Electronic Publication: 2021 Jan 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Acid-sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration.

• Authors : Zhao K; Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.; An R

Subjects: Pyroptosis*; Acid Sensing Ion Channels/Acid Sensing Ion Channels/Acid Sensing Ion Channels/*metabolism ; Inflammasomes/Inflammasomes/Inflammasomes/*metabolism

• Source: Cell proliferation [Cell Prolif] 2021 Jan; Vol. 54 (1), pp. e12941. Date of Electronic Publication: 2020 Oct 27.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

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Unveiling the Gut-Disc Axis: How Microbiome Dysbiosis Accelerates Intervertebral Disc Degeneration

• Authors : Sun Y; Li Z; Duan J

Subjects: intervertebral disc degeneration; microbiome; inflammation

• Source: Journal of Inflammation Research, Vol Volume 17, Pp 8271-8280 (2024)

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The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration.

• Authors : Liu C; Joint Center of South China University of Technology-The University of Western Australia for Regenerative Medicine Research, School of Medicine, South China University of Technology, Guangzhou 510006, China.; Liang G

Subjects: Cyclooxygenase 2/Cyclooxygenase 2/Cyclooxygenase 2/*physiology ; Inflammation/Inflammation/Inflammation/*complications ; Intervertebral Disc Degeneration/Intervertebral Disc Degeneration/Intervertebral Disc Degeneration/*etiology

• Source: Mediators of inflammation [Mediators Inflamm] 2021 Oct 18; Vol. 2021, pp. 2933199. Date of Electronic Publication: 2021 Oct 18 (Print Publication:Publisher: Wiley Country of Publication: United States NLM ID: 9209001 Publication Model: eCollection Cited Medium: Internet ISSN: 1466-1861

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The pathogenesis and targeted therapies of intervertebral disc degeneration induced by cartilage endplate inflammation

• Authors : Hantao Yang; Xuandu Chen; Jun Chen

Subjects: intervertebral disc degeneration; cartilage endplate; inflammation

• Source: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

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Rescue of nucleus pulposus cells from an oxidative stress microenvironment via glutathione-derived carbon dots to alleviate intervertebral disc degeneration

• Authors : Wenzhen Bu; Yu Shi; Xueping Huang

Subjects: Glutathione-doped carbon dot nanozymes; Intervertebral disc degeneration; Reactive oxygen species

• Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-14 (2024)

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