Authors : Lu S; CAS Key Laboratory of Microbial Physiological and Metabolic Engineering, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China.

Subjects: Hydroxymethylglutaryl CoA Reductases*/Hydroxymethylglutaryl CoA Reductases*/Hydroxymethylglutaryl CoA Reductases*/metabolism ; Mevalonic Acid*/Mevalonic Acid*/Mevalonic Acid*/metabolism ; Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/Saccharomyces cerevisiae*/enzymology

Source: Microbial biotechnology [Microb Biotechnol] 2022 Aug; Vol. 15 (8), pp. 2292-2306. Date of Electronic Publication: 2022 May 09.Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101316335 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

High-Risk Polymorphisms Associated with the Molecular Function of Human HMGCR Gene Infer the Inhibition of Cholesterol Biosynthesis.

Authors : Das KC; Molecular Biotechnology Division, National Institute of Biotechnology, Ganakbari, Ashulia, Savar, Dhaka-1349, Bangladesh.; Hossain MU

Subjects: Hydroxymethylglutaryl CoA Reductases*/Hydroxymethylglutaryl CoA Reductases*/Hydroxymethylglutaryl CoA Reductases*/genetics ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology ; Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use

Source: BioMed research international [Biomed Res Int] 2022 Jun 06; Vol. 2022, pp. 4558867. Date of Electronic Publication: 2022 Jun 06 (Print Publication: 2022).Publisher: Wiley Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium: Internet ISSN: 2314-6141

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase.

Authors : Maciejak A; Leszczynska A; Warchol I

Subjects: Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/*metabolism ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/Hydroxymethylglutaryl-CoA Reductase Inhibitors/*pharmacology ; Mevalonic Acid/Mevalonic Acid/Mevalonic Acid/*metabolism

Source: BMC biotechnology [BMC Biotechnol] 2013 Aug 30; Vol. 13, pp. 68. Date of Electronic Publication: 2013 Aug 30.Publisher: BioMed Central Country of Publication: England NLM ID: 101088663 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6750

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

HMGR overexpression and interference affect the expression of steroidogenic genes and cholesterol content in bovine intramuscular adipocytes.

Authors : Lin H; Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Lichen Region, Jinan, 250100, China.; Shandong Key Lab of Animal Disease Control and Breeding, Jinan, 250100, China.

Subjects: Adipocytes/Adipocytes/Adipocytes/*metabolism ; Cholesterol/Cholesterol/Cholesterol/*metabolism ; Gene Expression/Gene Expression/Gene Expression/*drug effects

Source: Scientific reports [Sci Rep] 2020 Oct 06; Vol. 10 (1), pp. 16606. Date of Electronic Publication: 2020 Oct 06.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Loss of HMG-CoA reductase in C. elegans causes defects in protein prenylation and muscle mitochondria.

Authors : Ranji P; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.; Rauthan M

Subjects: Gene Deletion* ; Protein Prenylation*; Caenorhabditis elegans/Caenorhabditis elegans/Caenorhabditis elegans/*physiology

Source: PloS one [PLoS One] 2014 Jun 11; Vol. 9 (2), pp. e100033. Date of Electronic Publication: 2014 Jun 11 (Print Publication: 2014).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production.

Authors : Song AA; Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, Serdang, Selangor Darul Ehsan, Malaysia.; Abdullah JO

Subjects: Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/*genetics ; Lactococcus lactis/Lactococcus lactis/Lactococcus lactis/*genetics ; Lactococcus lactis/Lactococcus lactis/Lactococcus lactis/*metabolism

Source: PloS one [PLoS One] 2012; Vol. 7 (12), pp. e52444. Date of Electronic Publication: 2012 Dec 26.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols.

Authors : Ohto C; Bio Research Lab., Toyota Motor Corporation, 1 Toyota-cho, Toyota, 471-8572, Japan.; Muramatsu M

Subjects: Fatty Alcohols/Fatty Alcohols/Fatty Alcohols/*metabolism ; Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/*biosynthesis ; Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/*genetics

Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2009 Apr; Vol. 82 (5), pp. 837-45. Date of Electronic Publication: 2008 Dec 16.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Up-regulation of an N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase enhances production of essential oils and sterols in transgenic Lavandula latifolia.

Authors : Muñoz-Bertomeu J; Departamento de Biología Vegetal, Facultad de Farmacia, Universidad de Valencia, 46100 Burjasot, Valencia, Spain.; Sales E

Subjects: Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/*metabolism ; Lavandula/Lavandula/Lavandula/*enzymology ; Oils, Volatile/Oils, Volatile/Oils, Volatile/*metabolism

Source: Plant biotechnology journal [Plant Biotechnol J] 2007 Nov; Vol. 5 (6), pp. 746-58. Date of Electronic Publication: 2007 Aug 22.Publisher: Wiley on behalf of the Society for Experimental Biology, Association of Applied Biologists Country of Publication: England NLM ID: 101201889 Publication

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

Regulation and degradation of HMGCo-A reductase.

Authors : Panda T; Department of Chemical Engineering, Indian Institute of Technology, Madras, Chennai, 600 036, India. ; Devi VA

Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2004 Dec; Vol. 66 (2), pp. 143-52. Date of Electronic Publication: 2004 Sep 30.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Print ISSN:

تفاصيل العنوان

اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي

Academic Journal

The metabolic imbalance underlying lesion formation in Arabidopsis thaliana overexpressing farnesyl diphosphate synthase (isoform 1S) leads to oxidative stress and is triggered by the developmental decline of endogenous HMGR activity.

Authors : Manzano D; Departament de Bioquímica i Biologia Molecular, Facultat de Farmàcia, Universitat de Barcelona, Av. Diagonal 643, 08028, Spain.; Fernández-Busquets X

Subjects: Alkyl and Aryl Transferases/Alkyl and Aryl Transferases/Alkyl and Aryl Transferases/*biosynthesis ; Arabidopsis/Arabidopsis/Arabidopsis/*metabolism ; Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/Hydroxymethylglutaryl CoA Reductases/*metabolism

Source: Planta [Planta] 2004 Oct; Vol. 219 (6), pp. 982-92. Date of Electronic Publication: 2004 Jun 15.Publisher: Springer-Verlag [etc.] Country of Publication: Germany NLM ID: 1250576 Publication Model: Print-Electronic Cited Medium: Print ISSN:

تفاصيل العنوان

اقرأ أكثر حفظ في قائمتي

نتائج البحث

فلترة النتائج

Enhancing fluxes through the mevalonate pathway in Saccharomyces cerevisiae by engineering the HMGR and β-alanine metabolism.

High-Risk Polymorphisms Associated with the Molecular Function of Human HMGCR Gene Infer the Inhibition of Cholesterol Biosynthesis.

The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase.

HMGR overexpression and interference affect the expression of steroidogenic genes and cholesterol content in bovine intramuscular adipocytes.

Loss of HMG-CoA reductase in C. elegans causes defects in protein prenylation and muscle mitochondria.

Overexpressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) in the lactococcal mevalonate pathway for heterologous plant sesquiterpene production.

Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols.

Up-regulation of an N-terminal truncated 3-hydroxy-3-methylglutaryl CoA reductase enhances production of essential oils and sterols in transgenic Lavandula latifolia.

Regulation and degradation of HMGCo-A reductase.

The metabolic imbalance underlying lesion formation in Arabidopsis thaliana overexpressing farnesyl diphosphate synthase (isoform 1S) leads to oxidative stress and is triggered by the developmental decline of endogenous HMGR activity.

اتصل بنا

اتبع