نتائج البحث

ALS-associated C21ORF2 variant disrupts DNA damage repair, mitochondrial metabolism, neuronal excitability and NEK1 levels in human motor neurons

• Authors : Zelina, Pavol; de Ruiter, Anna Aster; Kolsteeg, Christy ...

Subjects: Amyotrophic Lateral Sclerosis/genetics; Animals; DNA Damage

تفاصيل العنوان

X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease.

• Authors : Gromova, Anastasia; Cha, Byeonggu; Robinson, Erica M

Subjects: Motor Neurons; Animals; Mice

• Source: Acta neuropathologica communications, vol 11, iss 1

تفاصيل العنوان

Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects

• Authors : Workman, Michael J; Lim, Ryan G; Wu, Jie

Subjects: Biomedical and Clinical Sciences; Neurosciences; Stem Cell Research1191 - 1204.e5

• Source: Neuron, vol 111, iss 8

تفاصيل العنوان

Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons

• Authors : Liau, Ee Shan; Jin, Suoqin; Chen, Yen-Chung

Subjects: Biological Sciences; Biomedical and Clinical Sciences; Neurosciences

• Source: Nature Communications, vol 14, iss 1

تفاصيل العنوان

Downstream Effects of Mutations in SOD1 and TARDBP Converge on Gene Expression Impairment in Patient-Derived Motor Neurons.

• Authors : Dash, Banaja; Freischmidt, Axel; Weishaupt, Jochen H

Subjects: info:eu-repo/classification/ddc/540; Amyotrophic Lateral Sclerosis: genetics; DNA-Binding Proteins: geneticsDE

• Source: International journal of molecular sciences 23(17), 9652 (2022). doi:10.3390/ijms23179652 special issue: "Neurological Diseases: A Molecular Genetic Perspective"

تفاصيل العنوان

Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

• Authors : Allodi, Ilary; Montañana-Rosell, Roser; Selvan, Raghavendra

Subjects: Amyotrophic Lateral Sclerosis (ALS)/genetics; Animals; Disease Models

• Source: Allodi , I , Montañana-Rosell , R , Selvan , R , Löw , P & Kiehn , O 2021 , ' Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast

تفاصيل العنوان

Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast motor neurons

• Authors : Allodi, Ilary; Montañana-Rosell, Roser; Selvan, Raghavendra

Subjects: Amyotrophic Lateral Sclerosis (ALS)/genetics; Animals; Disease Models

• Source: Allodi , I , Montañana-Rosell , R , Selvan , R , Löw , P & Kiehn , O 2021 , ' Locomotor deficits in a mouse model of ALS are paralleled by loss of V1-interneuron connections onto fast

تفاصيل العنوان

Recruitment order of motor neurons promoted by epidural stimulation in individuals with spinal cord injury.

• Authors : Ibáñez, J; Angeli, CA; Harkema, SJ

Subjects: epidural stimulation; motor neuron; recruitment orderUnited States

• Source: 1110 ; 1100

تفاصيل العنوان

Nucleolar stress in C9orf72 and sporadic ALS spinal motor neurons precedes TDP-43 mislocalization

• Authors : Aladesuyi Arogundade, Olubankole; Nguyen, Sandra; Leung, Ringo

Subjects: Biomedical and Clinical Sciences; Neurosciences; Neurodegenerative

• Source: Acta Neuropathologica Communications, vol 9, iss 1

تفاصيل العنوان

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

• Authors : Hyunah Lee; Hye Yeong Lee; Byeong Eun Lee

Subjects: Animals; Cell Transplantation; Disease Models

تفاصيل العنوان