نتائج البحث

FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops.

• Authors : Pan, Xiaolei; Chen, Yun; Biju, Beena

Subjects: BRCA2 Protein; Biomarkers; Tumor

• Source: Scientific Reports. 9(1)

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A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2

• Authors : Dubois, Emilie L; Guitton-Sert, Laure; Béliveau, Mariline

Subjects: Biochemistry and Cell Biology; Biological Sciences; Hematology

• Source: Nucleic Acids Research. 47(14)

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Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia

• Authors : Pouliot, Gayle P; Degar, James; Hinze, Laura

Subjects: Biological Sciences; Biomedical and Clinical Sciences; Genetics

• Source: PLOS ONE. 14(11)

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FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine.

• Authors : Peña-Gómez, María José; Moreno-Gordillo, Paula; Narmontė, Milda

Subjects: DNA Demethylation; DNA Replication; Deoxycytidine

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Replication stress by Py–Im polyamides induces a non-canonical ATR-dependent checkpoint response

• Authors : Martínez, Thomas F; Phillips, John W; Karanja, Kenneth K

Subjects: Biochemistry and Cell Biology; Biological Sciences; Genetics

• Source: Nucleic Acids Research. 42(18)

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FANCD2 modulates the mitochondrial stress response to prevent common fragile site instability

• Authors : Fernandes P.; Miotto B.; Saint-Ruf C. ...

Subjects: DNA Damage; Fanconi Anemia Complementation Group D2 Protein; Gene Expression Regulation

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The SWI/SNF chromatin remodeling complex helps resolve R-loop-mediated transcription-replication conflicts.

• Authors : Bayona-Feliu, Aleix; Barroso, Sonia; Muñoz, Sergio

Subjects: Adenosine Triphosphatases; Chromatin; Chromatin Assembly and Disassembly

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The fanconi anemia pathway limits human papillomavirus replication.

• Authors : Hoskins, Elizabeth; Morreale, Richard; Werner, Stephen

Subjects: Brazil; Carcinoma; Squamous Cell

• Source: Journal of Virology. 86(15)

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The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination

• Authors : Tamara Sijacki; Pablo Alcón; Zhuo A. Chen

Subjects: Fanconi Anemia; Polynucleotide 5'-Hydroxyl-Kinase; DNA Repair

• Source: Nat Struct Mol BiolSijacki, T, Alcón, P, Chen, Z A, Mclaughlin, S H, Shakeel, S, Rappsilber, J & Passmore, L A 2022, ' The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it

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FANCB (FA complementation group B)

• Authors : van Twest, Sylvie; Deans, Andrew; St Vincent's Institute of Medical Research, 9 Princes St, Fitzroy VIC 3065, Australia

Subjects: FANCB; Fanconi Anemia; Ubiquitination

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