نتائج البحث

Anti-tumour activity of Panobinostat in oesophageal adenocarcinoma and squamous cell carcinoma cell lines.

• Authors : Lopes N; Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP) - (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC), Research Center-LAB 3, F Bdg, 1st Floor, Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Portugal.; Salta S

Subjects: Panobinostat*/Panobinostat*/Panobinostat*/pharmacology ; Panobinostat*/Panobinostat*/Panobinostat*/therapeutic use ; Panobinostat*/Panobinostat*/Panobinostat*/administration & dosage Adenocarcinoma Of Esophagus

• Source: Clinical epigenetics [Clin Epigenetics] 2024 Aug 03; Vol. 16 (1), pp. 102. Date of Electronic Publication: 2024 Aug 03.Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083

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HDACi combination therapy with IDO1i remodels the tumor microenvironment and boosts antitumor efficacy in colorectal cancer with microsatellite stability.

• Authors : Liang R; Department of Gastrointestinal Surgery, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510630, P.R. China.; Department of Gastrointestinal Surgery, Lingnan Hospital, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, P.R. China.

Subjects: Tumor Microenvironment*/Tumor Microenvironment*/Tumor Microenvironment*/drug effects ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/drug therapy ; Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/pathology

• Source: Journal of nanobiotechnology [J Nanobiotechnology] 2024 Dec 16; Vol. 22 (1), pp. 753. Date of Electronic Publication: 2024 Dec 16.Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155

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Therapeutic role of histone deacetylase inhibition in an in vitro model of Graves' orbitopathy.

• Authors : Byeon HJ; Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of Korea.; Choi SH

Subjects: Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/metabolism ; Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/drug therapy ; Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/genetics

• Source: Molecular medicine reports [Mol Med Rep] 2024 Dec; Vol. 30 (6). Date of Electronic Publication: 2024 Sep 27.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation.

• Authors : Harttrampf AC; Gustave Roussy Cancer Center, INSERM U1015, Université Paris-Saclay, Villejuif, France.; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, 114 Rue Edouard Vaillant, 94805, Villejuif, France.

Subjects: Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/Epithelial-Mesenchymal Transition/*drug effects ; Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/*therapeutic use ; Panobinostat/Panobinostat/Panobinostat/*therapeutic use

• Source: BMC cancer [BMC Cancer] 2021 Jul 20; Vol. 21 (1), pp. 833. Date of Electronic Publication: 2021 Jul 20.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Synergistic Cytotoxicity of Histone Deacetylase and Poly-ADP Ribose Polymerase Inhibitors and Decitabine in Breast and Ovarian Cancer Cells: Implications for Novel Therapeutic Combinations.

• Authors : Valdez BC; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.; Tsimberidou AM

Subjects: Decitabine*/Decitabine*/Decitabine*/pharmacology ; Drug Synergism* ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 26; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Panobinostat Attenuates Experimental Autoimmune Encephalomyelitis in Mice via Suppressing Oxidative Stress-Related Neuroinflammation and Mitochondrial Dysfunction.

• Authors : Shen, Yanjia¹ (AUTHOR) ; Zhao, Jiaying¹ (AUTHOR); Yang, Ran¹ (AUTHOR)

Subjects: *T helper cells; *HISTONE deacetylase inhibitors; *CENTRAL nervous system

• Source: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12035. 14p.

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Chondroprotective Effects of a Histone Deacetylase Inhibitor, Panobinostat, on Pain Behavior and Cartilage Degradation in Anterior Cruciate Ligament Transection-Induced Experimental Osteoarthritic Rats.

• Authors : Wen ZH; Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.; Huang JS

Subjects: Anterior Cruciate Ligament/Anterior Cruciate Ligament/Anterior Cruciate Ligament/*drug effects ; Cartilage, Articular/Cartilage, Articular/Cartilage, Articular/*drug effects ; Chondrocytes/Chondrocytes/Chondrocytes/*drug effects

• Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jul 07; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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EphA2- and HDAC-Targeted Combination Therapy in Endometrial Cancer.

• Authors : Joseph R; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.; Dasari SK

Subjects: Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/drug therapy ; Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/genetics ; Endometrial Neoplasms*/Endometrial Neoplasms*/Endometrial Neoplasms*/pathology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 20; Vol. 25 (2). Date of Electronic Publication: 2024 Jan 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma.

• Authors : Demir, Salih¹ (AUTHOR); Hotes, Alina¹ (AUTHOR); Schmid, Tanja¹ (AUTHOR)

• Source: Journal of Experimental & Clinical Cancer Research (17569966). 11/12/2024, Vol. 43 Issue 1, p1-16. 16p.

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Phase-I and randomized phase-II trial of panobinostat in combination with ICE (ifosfamide, carboplatin, etoposide) in relapsed or refractory classical Hodgkin lymphoma.

• Authors : Hu B; a Department of Lymphoma and Myeloma , The University of Texas MD Anderson Cancer Center , Houston , TX , USA.; Younes A

Subjects: Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use ; Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/Histone Deacetylase Inhibitors/*therapeutic use ; Hodgkin Disease/Hodgkin Disease/Hodgkin Disease/*drug therapy ICE protocol 3

• Source: Leukemia & lymphoma [Leuk Lymphoma] 2018 Apr; Vol. 59 (4), pp. 863-870. Date of Electronic Publication: 2017 Aug 09.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 9007422 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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