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Academic Journal

Therapeutic role of histone deacetylase inhibition in an in vitro model of Graves' orbitopathy.

  • Authors : Byeon HJ; Department of Ophthalmology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Republic of Korea.; Choi SH

Subjects: Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/metabolism ; Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/drug therapy ; Graves Ophthalmopathy*/Graves Ophthalmopathy*/Graves Ophthalmopathy*/genetics

  • Source: Molecular medicine reports [Mol Med Rep] 2024 Dec; Vol. 30 (6). Date of Electronic Publication: 2024 Sep 27.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Fermented Wheat Germ Protein with Histone Deacetylase Inhibitor AR42 Demonstrates Enhanced Cytotoxicity against Lymphoma Cells In Vitro and In Vivo.

  • Authors : Meckler JF; Division of Hematology and Oncology, Department of Internal Medicine, University of California Davis School of Medicine, Sacramento, CA 95817, USA.; Levis DJ

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Lymphoma*/Lymphoma*/Lymphoma*/drug therapy ; Lymphoma*/Lymphoma*/Lymphoma*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 18; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Drug repositioning identifies histone deacetylase inhibitors that promote innate immunity in non-tuberculous mycobacterial infection.

  • Authors : Rodriguez-Carlos A; Medical Research Unit-Zacatecas, Mexican Institute for Social Security-IMSS, Zacatecas, Mexico.; Raúl A

Subjects: Immunity, Innate*/Immunity, Innate*/Immunity, Innate*/drug effects ; Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/immunology ; Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/Mycobacterium Infections, Nontuberculous*/microbiology

  • Source: Canadian journal of microbiology [Can J Microbiol] 2024 Jul 01; Vol. 70 (7), pp. 252-261. Date of Electronic Publication: 2024 Jun 10.Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 0372707 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Preconditioning of Human Umbilical Cord Mesenchymal Stem Cells with a Histone Deacetylase Inhibitor: Valproic Acid.

  • Authors : Işıldar B; Department of Histology and Embryology, İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, İstanbul, Türkiye.; Department of Histology and Embryology, Balıkesir University Faculty of Medicine, Balıkesir, Türkiye.

Subjects: Valproic Acid*/Valproic Acid*/Valproic Acid*/pharmacology ; Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/Mesenchymal Stem Cells*/drug effects ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology

  • Source: Balkan medical journal [Balkan Med J] 2024 Sep 06; Vol. 41 (5), pp. 369-376.Publisher: Galenos Publishing House Country of Publication: Turkey NLM ID: 101571817 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Synergistic Cytotoxicity of Histone Deacetylase and Poly-ADP Ribose Polymerase Inhibitors and Decitabine in Breast and Ovarian Cancer Cells: Implications for Novel Therapeutic Combinations.

  • Authors : Valdez BC; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.; Tsimberidou AM

Subjects: Decitabine*/Decitabine*/Decitabine*/pharmacology ; Drug Synergism* ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 26; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Histone deacetylase as emerging pharmacological therapeutic target for neuropathic pain: From epigenetic to selective drugs.

  • Authors : Zhang W; Department of Anesthesiology and Pain Medicine, Hubei Key Laboratory of Geriatric Anesthesia and Perioperative Brain Health, and Wuhan Clinical Research Center for Geriatric Anesthesia, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.; Jiao B

Subjects: Epigenesis, Genetic*/Epigenesis, Genetic*/Epigenesis, Genetic*/drug effects ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use

  • Source: CNS neuroscience & therapeutics [CNS Neurosci Ther] 2024 May; Vol. 30 (5), pp. e14745.Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101473265 Publication Model: Print Cited Medium: Internet ISSN: 1755-5949

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Academic Journal

Advances in targeting histone deacetylase for treatment of solid tumors.

  • Authors : Shi MQ; Department of Breast Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032, China.

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use ; Histone Deacetylases*/Histone Deacetylases*/Histone Deacetylases*/metabolism

  • Source: Journal of hematology & oncology [J Hematol Oncol] 2024 May 31; Vol. 17 (1), pp. 37. Date of Electronic Publication: 2024 May 31.Publisher: Biomed Central Country of Publication: England NLM ID: 101468937 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-8722

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Academic Journal

Molecular heterogeneity of BCL2/MYC double expressor lymphoma underlies sensitivity to histone deacetylase inhibitor.

  • Authors : Shi ZY; Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Fang Y

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/therapeutic use ; Proto-Oncogene Proteins c-bcl-2*/Proto-Oncogene Proteins c-bcl-2*/Proto-Oncogene Proteins c-bcl-2*/genetics

  • Source: Clinical and translational medicine [Clin Transl Med] 2024 Jun; Vol. 14 (6), pp. e1691.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Academic Journal

Rapid Determination of Kinetic Constants for Slow-Binding Inhibitors and Inactivators of Human Histone Deacetylase 8.

  • Authors : Kopranovic A; Department of Chemical Engineering and Biotechnology, University of Applied Sciences Darmstadt, Haardtring 100, 64295 Darmstadt, Germany.; Meyer-Almes FJ

Subjects: Histone Deacetylases*/Histone Deacetylases*/Histone Deacetylases*/metabolism ; Histone Deacetylases*/Histone Deacetylases*/Histone Deacetylases*/chemistry ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 21; Vol. 25 (11). Date of Electronic Publication: 2024 May 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Design, Synthesis, and Biological Evaluation of HDAC Inhibitors Containing Natural Product-Inspired N -Linked 2-Acetylpyrrole Cap.

  • Authors : Zhang H; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing 210023, China.; State Key Laboratory of Drug Research, Ethnomedicine and Biofunctional Molecule Research Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, China.

Subjects: Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemistry ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/pharmacology ; Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/Histone Deacetylase Inhibitors*/chemical synthesis

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Sep 30; Vol. 29 (19). Date of Electronic Publication: 2024 Sep 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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