نتائج البحث

Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1).

• Authors : Brennig S; Reprogramming and Gene Therapy Group, REBIRTH Cluster-of Excellence, Hannover Medical School, Carl-Neuberg-Str.1, Hannover, D-30625, Germany.; Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*genetics ; Cytidine Deaminase/Cytidine Deaminase/Cytidine Deaminase/*genetics ; Hematopoietic Stem Cells/Hematopoietic Stem Cells/Hematopoietic Stem Cells/*drug effects

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2015 Dec 12; Vol. 34, pp. 148. Date of Electronic Publication: 2015 Dec 12.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

تفاصيل العنوان

Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O(6)-methylguanine-DNA methyltransferase(P140K).

• Authors : Maier P; Pharmacology of Cancer Treatment, DKFZ, German Cancer Research Center, Heidelberg, Germany. ; Spier I

Subjects: ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*genetics ; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*adverse effects ; Cytoprotection/Cytoprotection/Cytoprotection/*genetics

• Source: Gene therapy [Gene Ther] 2010 Mar; Vol. 17 (3), pp. 389-99. Date of Electronic Publication: 2009 Oct 29.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

تفاصيل العنوان

Chemoprotection effect of multidrug resistance 1 (MDR1) gene transfer to hematopoietic progenitor cells and engrafted in mice with cancer allows intensified chemotherapy.

• Authors : Guo C; The Laboratory of Surgery, Children's Hospital of Chongqing Medical University, Chongqing, PR China. ; Jin X

Subjects: Hematopoietic Stem Cell Transplantation*; ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/ATP Binding Cassette Transporter, Subfamily B, Member 1/*genetics ; Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/Antibiotics, Antineoplastic/*therapeutic use

• Source: Cancer investigation [Cancer Invest] 2006 Nov; Vol. 24 (7), pp. 659-68.Publisher: Taylor & Francis Country of Publication: England NLM ID: 8307154 Publication Model: Print Cited Medium: Print ISSN: 0735-7907 (Print)

تفاصيل العنوان

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells.

• Authors : Abonour R; Department of Medicine, Howard Hughes Medical Institute, Indiana University School of Medicine, 1044 W. Walnut, Rm. 402, Indianapolis, IN 46202, USA.; Williams DA

Subjects: Gene Transfer Techniques* ; Genes, MDR* ; Genetic Vectors*

• Source: Nature medicine [Nat Med] 2000 Jun; Vol. 6 (6), pp. 652-8.Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print Cited Medium: Print ISSN:

تفاصيل العنوان

A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents.

• Authors : Jelinek J; Institute of Haematology and Blood Transfusion, Praha, Czech Republic.; Rafferty JA

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Drug Resistance, Multiple/Drug Resistance, Multiple/Drug Resistance, Multiple/*genetics ; Hematopoietic Stem Cells/Hematopoietic Stem Cells/Hematopoietic Stem Cells/*physiology

• Source: Gene therapy [Gene Ther] 1999 Aug; Vol. 6 (8), pp. 1489-93.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print Cited Medium: Print ISSN: 0969-7128

تفاصيل العنوان

Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O6-methylguanine-DNA methyltransferaseP140K.

• Authors : Maier, P.^1,2 ; Spier, I.¹; Laufs, S.³

• Source: Gene Therapy. Mar2010, Vol. 17 Issue 3, p389-399. 11p. 3 Charts, 3 Graphs.

تفاصيل العنوان

Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1)

• Authors : Nico Lachmann; Axel Schambach; Miriam Hetzel

Subjects: Cancer Research; Myeloid; DNA, Complementary

• Source: Journal of Experimental & Clinical Cancer Research : CR

تفاصيل العنوان

Optimization of multidrug resistance 1 gene transfer confers chemoprotection to human hematopoietic cells engrafted in immunodeficient mice.

• Authors : Hualing Zhang¹; Zeqing Wen¹ ; Shougang Tan²

• Source: European Journal of Haematology. May2007, Vol. 78 Issue 5, p432-439. 8p. 4 Graphs.

تفاصيل العنوان

Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O6-methylguanine-DNA methyltransferaseP140K.

• Authors : Maier, P.^1,2 ; Spier, I.¹; Laufs, S.³

Subjects: *HEMATOPOIETIC stem cells; *MULTIDRUG resistance; *METHYLTRANSFERASES

• Source: Gene Therapy. Mar2010, Vol. 17 Issue 3, p389-399. 11p. 3 Charts, 3 Graphs.

تفاصيل العنوان

Efficient retrovirus-mediated transfer of the multidrug resistance 1 gene into autologous human long-term repopulating hematopoietic stem cells

• Authors : David R. Williams; Jun Chen; Michael J. Robertson

Subjects: Adult; Time Factors; Adolescent

• Source: Nature medicine. 6(6)

تفاصيل العنوان