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Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients With Newly Diagnosed Glioblastoma (2-THE-TOP) (2-THE-TOP)

• Authors : NovoCure Ltd.

• Source: Phase 2, Single Arm, Historically Controlled Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus

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OKN-007 in Combination With Adjuvant Temozolomide Chemoradiotherapy for Newly Diagnosed Glioblastoma

• Source: Feasibility Pilot Study of OKN-007 in Combination With Adjuvant Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed

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JK-1201I Combined with Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma Multiforme (GBM)

• Source: A Multicenter, Single Arm, Open-label, Dose-escalation Phase 2 Study of JK-1201I Combined with Adjuvant Temozolomide in Patients with

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Effect of long-term adjuvant temozolomide chemotherapy on primary glioblastoma patient survival.

• Authors : Huang B; Department of Neurosurgery, Fujian Medical University Union Hospital, No. 29 Xinquan Road, Gulou District, Fuzhou City, Fujian Province, China.; Yu Z

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy; Antineoplastic Agents, Alkylating/Antineoplastic Agents, Alkylating/Antineoplastic Agents, Alkylating/therapeutic use

• Source: BMC neurology [BMC Neurol] 2021 Nov 02; Vol. 21 (1), pp. 424. Date of Electronic Publication: 2021 Nov 02.Publisher: BioMed Central Country of Publication: England NLM ID: 100968555 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2377

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Outcomes in Elderly Patients with Glioblastoma Multiforme Treated with Short-Course Radiation Alone Compared to Short-Course Radiation and Concurrent and Adjuvant Temozolomide Based on Performance Status and Extent of Resection.

• Authors : Mir T; Juravinski Cancer Center, Department of Oncology, Radiation Oncology, McMaster University, 699 Concession St., Hamilton, ON L8V5C2, Canada.; Pond G

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/drug therapy ; Glioblastoma*/Glioblastoma*/Glioblastoma*/drug therapy; Aged

• Source: Current oncology (Toronto, Ont.) [Curr Oncol] 2021 Jun 26; Vol. 28 (4), pp. 2399-2408. Date of Electronic Publication: 2021 Jun 26.Publisher: MDPI Country of Publication: Switzerland NLM ID: 9502503 Publication Model: Electronic Cited Medium: Internet ISSN: 1718-7729

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SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (SURVIVE)

• Authors : Translational Drug Development; Merit

• Source: Prospective Randomized Placebo-Controlled Trial of SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed

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Prognostic Value of Pretreatment Systemic Immune-Inflammation Index in Glioblastoma Multiforme Patients Undergoing Postneurosurgical Radiotherapy Plus Concurrent and Adjuvant Temozolomide.

• Authors : Topkan E; Başkent University Medical Faculty, Department of Radiation Oncology, Adana, Turkey.; Besen AA

Subjects: Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*metabolism ; Glioblastoma/Glioblastoma/Glioblastoma/*metabolism ; Inflammation/Inflammation/Inflammation/*metabolism

• Source: Mediators of inflammation [Mediators Inflamm] 2020 May 23; Vol. 2020, pp. 4392189. Date of Electronic Publication: 2020 May 23 (Print Publication: 2020).Publisher: Wiley Country of Publication: United States NLM ID: 9209001 Publication Model: eCollection Cited Medium: Internet ISSN: 1466-1861

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Metformin, Neo-adjuvant Temozolomide and Hypo- Accelerated Radiotherapy Followed by Adjuvant TMZ in Patients With GBM

• Authors : George Shenouda, Principal Investigator

• Source: Metformin and Neo-adjuvant Temozolomide and Hypofractionated Accelerated Limited-margin Radiotherapy Followed by

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Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma.

• Authors : Massey SC; Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America.; White H

Subjects: Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/diagnostic imaging ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/drug therapy ; Brain Neoplasms*/Brain Neoplasms*/Brain Neoplasms*/metabolism

• Source: PloS one [PLoS One] 2020 Mar 27; Vol. 15 (3), pp. e0230492. Date of Electronic Publication: 2020 Mar 27 (Print Publication: 2020).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Feasibility study of finalizing the extended adjuvant temozolomide based on methionine positron emission tomography (Met-PET) findings in patients with glioblastoma.

• Authors : Hirono S; Division of Neurological Surgery, Chiba Cancer Center, 666-2 Nitona-cho, Chuo-ku, Chiba, 260-8717, Japan. .; Hasegawa Y

Subjects: Antineoplastic Agents, Alkylating/Antineoplastic Agents, Alkylating/Antineoplastic Agents, Alkylating/*therapeutic use ; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*diagnostic imaging ; Brain Neoplasms/Brain Neoplasms/Brain Neoplasms/*drug therapy

• Source: Scientific reports [Sci Rep] 2019 Nov 28; Vol. 9 (1), pp. 17794. Date of Electronic Publication: 2019 Nov 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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