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Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells.

• Authors : Hollerer, Ina; Barker, Juliet C; Jorgensen, Victoria

Subjects: Humans; Histones; Chromatin Immunoprecipitation

• Source: G3 (Bethesda, Md.). 9(4)

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Exploring the underlying biology of cancer and potential therapeutic strategies: a special issue focused on mechanism-based studies

• Authors : Gao Daming; Ge Gaoxiang

Subjects: Biochemistry; QD415-436; Genetics

• Source: Acta Biochimica et Biophysica Sinica, Vol 55, Pp 891-892 (2023)

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Evidence for an Integrated Gene Repression Mechanism Based on mRNA Isoform Toggling in Human Cells

• Authors : Ina Hollerer; Juliet C. Barker; Victoria Jorgensen

Subjects: gene expression regulation; MDM2; LUTI

• Source: G3: Genes, Genomes, Genetics, Vol 9, Iss 4, Pp 1045-1053 (2019)

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Turnover and Inactivation Mechanisms for ( S )‑3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase

• Authors : Sida Shen (1408936); Arseniy Butrin (8506680); Peter F. Doubleday (1345620)

Subjects: Biophysics; Biochemistry; Microbiology

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Back to the future: mechanism-based, mutation-specific combination chemoprevention with a synthetic lethality approach.

• Authors : Meyskens, Frank L, Jr; Gerner, Eugene W

Subjects: Apoptosis; Biomimetics; Genes

• Source: Cancer prevention research (Philadelphia, Pa.). 4(5)

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In silico design of the first DNA-independent mechanism-based inhibitor of mammalian DNA methyltransferase Dnmt1.

• Authors : Miletić, Vedran¹ ; Odorčić, Ivica²; Nikolić, Patrik²

Subjects: *DNA methylation; *MAMMAL genetics; *DNA methyltransferases

• Source: PLoS ONE. 4/11/2017, Vol. 12 Issue 4, p1-21. 21p.

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Attention Mechanism-Based Graph Neural Network Model for Effective Activity Prediction of SARS-CoV‑2 Main Protease Inhibitors: Application to Drug Repurposing as Potential COVID-19 Therapy

• Authors : Yanling Wu; Kun Li; Menglong Li

Subjects: Biophysics; Biochemistry; Genetics

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Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data

• Authors : Narayanaswamy Srinivasan; Sneha Bheemireddy; Sohini Chakraborti

Subjects: 0301 basic medicine; Coronavirus disease 2019 (COVID-19); medicine.medical_treatment

• Source: Molecular Omics

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Establishing model mechanism‐based causal linkages between APAP‐induced hepatic necrosis and serum ALT

• Authors : Glen E. P. Ropella; C. Anthony Hunt; Andrew K. Smith

Subjects: Chemistry; Genetics; Mechanism based

• Source: The FASEB Journal. 33

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Advances in flux balance analysis by integrating machine learning and mechanism-based models

• Authors : Ankur Sahu; Nadine Töpfer; Jedrzej Szymanski

Subjects: Flux balance analysis; Modeling language; Computer science

• Source: Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4626-4640 (2021)Computational and Structural Biotechnology JournalComputational and structural biotechnology journal,

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