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Academic Journal

Cas9 off-target binding to the promoter of bacterial genes leads to silencing and toxicity.

  • Authors : Rostain W; Synthetic Biology, Institut Pasteur, Université Paris Cité, CNRS UMR 6047, 75015 Paris, France.; Grebert T

Subjects: CRISPR-Cas Systems*/CRISPR-Cas Systems*/CRISPR-Cas Systems*/genetics ; Genetic Engineering*/Genetic Engineering*/Genetic Engineering*/methods; Animals

  • Source: Nucleic acids research [Nucleic Acids Res] 2023 Apr 24; Vol. 51 (7), pp. 3485-3496.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

The discovery and development of the CRISPR system in applications in genome manipulation.

  • Authors : Lau V; Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.; Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB R3E 3P4, Canada.

Subjects: CRISPR-Cas Systems* ; Clustered Regularly Interspaced Short Palindromic Repeats* ; Genome*

  • Source: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2017 Apr; Vol. 95 (2), pp. 203-210. Date of Electronic Publication: 2016 Oct 28.Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 8606068 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

CRISPR-associated nucleases: the Dawn of a new age of efficient crop improvement.

Subjects: CRISPR-Cas Systems* ; Gene Editing* ; Genome, Plant*

  • Source: Transgenic research [Transgenic Res] 2020 Feb; Vol. 29 (1), pp. 1-35. Date of Electronic Publication: 2019 Nov 01.Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9209120 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

A Cas9-based toolkit to program gene expression in Saccharomyces cerevisiae.

  • Authors : Reider Apel A; DOE Joint BioEnergy Institute, Emeryville, California, CA 94608, USA.; Biological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, California, CA 94720, USA.

Subjects: CRISPR-Cas Systems*; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/*genetics ; DNA, Fungal/DNA, Fungal/DNA, Fungal/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2017 Jan 09; Vol. 45 (1), pp. 496-508. Date of Electronic Publication: 2016 Nov 28.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

  • Authors : McKenna A; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Findlay GM

Subjects: Bacterial Proteins* ; CRISPR-Cas Systems* ; Cell Lineage*

  • Source: Science (New York, N.Y.) [Science] 2016 Jul 29; Vol. 353 (6298), pp. aaf7907. Date of Electronic Publication: 2016 May 26.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Efficient fdCas9 Synthetic Endonuclease with Improved Specificity for Precise Genome Engineering.

  • Authors : Aouida M; Laboratory for Genome Engineering, Division of Biological Sciences & Center for Desert Agriculture, 4700 King Abdullah University of Science and Technology, Thuwal, 23955-6900, Kingdom of Saudi Arabia.; Eid A

Subjects: CRISPR-Cas Systems*; Endonucleases/Endonucleases/Endonucleases/*metabolism ; Genetic Engineering/Genetic Engineering/Genetic Engineering/*methods

  • Source: PloS one [PLoS One] 2015 Jul 30; Vol. 10 (7), pp. e0133373. Date of Electronic Publication: 2015 Jul 30 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Genome editing through large insertion leads to the skipping of targeted exon.

  • Authors : Uddin B; Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), DKFZ-ZMBH Allianz, Im Neuenheimer Feld 282, 69120, Heidelberg, Germany. .; The Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology (HBIGS), University of Heidelberg, Heidelberg, 69120, Germany. .

Subjects: Mutagenesis, Insertional* ; RNA Editing*; Endonucleases/Endonucleases/Endonucleases/*metabolism

  • Source: BMC genomics [BMC Genomics] 2015 Dec 21; Vol. 16, pp. 1082. Date of Electronic Publication: 2015 Dec 21.Publisher: BioMed Central Country of Publication: England NLM ID: 100965258 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2164

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Academic Journal

Dynamics of CRISPR-Cas9 genome interrogation in living cells.

  • Authors : Knight SC; Department of Chemistry, University of California, Berkeley, CA, USA.; Xie L

Subjects: CRISPR-Cas Systems* ; DNA Cleavage* ; Genetic Engineering*

  • Source: Science (New York, N.Y.) [Science] 2015 Nov 13; Vol. 350 (6262), pp. 823-6.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium:

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Academic Journal

Conformational control of DNA target cleavage by CRISPR-Cas9.

  • Authors : Sternberg SH; Department of Chemistry, University of California, Berkeley, California 94720, USA.; LaFrance B

Subjects: CRISPR-Cas Systems* ; DNA Cleavage* ; Genetic Engineering*

  • Source: Nature [Nature] 2015 Nov 05; Vol. 527 (7576), pp. 110-3. Date of Electronic Publication: 2015 Oct 28.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases.

  • Authors : Mock U; Research Dept. Cell and Gene Therapy, Clinic for Stem Cell Transplantation, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany.; Riecken K

Subjects: Genetic Engineering* ; Genetic Vectors*; Endonucleases/Endonucleases/Endonucleases/*metabolism

  • Source: Scientific reports [Sci Rep] 2014 Sep 18; Vol. 4, pp. 6409. Date of Electronic Publication: 2014 Sep 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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