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Pharmacological Targeting of the RAGE-NFκB Signalling Axis Impedes Monocyte Activation under Diabetic Conditions through the Repression of SHP-2 Tyrosine Phosphatase Function

• Authors : Marc Dorenkamp; Madina Nasiry; Dilvin Semo

Subjects: SHP-2; methylglyoxal; T2DM

• Source: CellsVolume 12Issue 3Pages: 513

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Siglec-6 Signaling Uses Src Kinase Tyrosine Phosphorylation and SHP-2 Recruitment

• Authors : Adrianne L. Stefanski; Michael D. Renecle; Anita Kramer

Subjects: Sialic Acid Binding Immunoglobulin-like Lectins; Placenta; Protein Tyrosine Phosphatase, Non-Receptor Type 6

• Source: Cells; Volume 11; Issue 21; Pages: 3427

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The Phosphatase SHP-2 Activates HIF-1α in Wounds In Vivo by Inhibition of 26S Proteasome Activity

• Authors : Alexander Pfeifer; Hanna Mannell; Bjoern F. Kraemer

Subjects: Male; 0301 basic medicine; Angiogenesis

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 20, Iss 18, p 4404 (2019)

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Design, Synthesis, Biological Activity and Molecular Dynamics Studies of Specific Protein Tyrosine Phosphatase 1B Inhibitors over SHP-2

• Authors : Shu-Qing Wang; Liu Wei; Wen-Bo Liu

Subjects: Silicon; synthesis; Protein Conformation

• Source: International Journal of Molecular SciencesInternational Journal of Molecular Sciences, Vol 14, Iss 6, Pp 12661-12674 (2013)Volume 14Issue 6Pages 12661-12674

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Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis

• Authors : Heun, Yvonn; Pircher, Joachim; Czermak, Thomas ...

Subjects: General Biochemistry, Genetics and Molecular Biology; General Medicine

• Source: EBioMedicine ; volume 42, page 120-132 ; ISSN 2352-3964

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Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population

• Authors : Jiang, Jing; Jia, Zhi-Fang; Kong, Fei

Subjects: Gastroenterology; General Medicine

• Source: BMC Gastroenterology ; volume 12, issue 1 ; ISSN 1471-230X

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Ras/RAF/MEK/ERK pathway; Src homology protein tyrosine phosphatase 2 (SHP-2; SHPTP2; PTPN11)

Subjects: General Medicine

• Source: Science-Business eXchange ; volume 7, issue 46, page 1356-1356 ; ISSN 1945-3477

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Src homology protein tyrosine phosphatase 2 (SHP-2; SHPTP2; PTPN11)

Subjects: General Medicine

• Source: Science-Business eXchange ; volume 6, issue 36, page 991-991 ; ISSN 1945-3477

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PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?

• Authors : Calò, Lorenzo A; Bordin, Luciana; Davis, Paul A

Subjects: Pharmacology (medical); Biochemistry (medical); Cell Biology

• Source: Journal of Biomedical Science ; volume 18, issue 1, page 38 ; ISSN 1423-0127

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The structural insights of stem cell factor receptor (c-Kit) interaction with tyrosine phosphatase-2 (Shp-2): An in silico analysis

• Authors : Pati, Soumya; Gurudutta, Gangenahalli U; Kalra, Om P

Subjects: General Biochemistry, Genetics and Molecular Biology; General Medicine

• Source: BMC Research Notes ; volume 3, issue 1, page 14 ; ISSN 1756-0500

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