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  • 1-10 ل  175 نتائج ل ""CHECKPOINT kinase 1""

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Subject : gene expression regulation, neoplastic
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Academic Journal

Uncovering miRNA-mRNA Regulatory Networks Related to Olaparib Resistance and Resensitization of BRCA2MUT Ovarian Cancer PEO1-OR Cells with the ATR/CHK1 Pathway Inhibitors.

  • Authors : Biegała Ł; Department of Medical Biophysics, Institute of Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland.; Doctoral School of Exact and Natural Sciences, University of Lodz, Jana Matejki 21/23, 90-237 Lodz, Poland.

Subjects: Phthalazines*/Phthalazines*/Phthalazines*/pharmacology ; Phthalazines*/Phthalazines*/Phthalazines*/therapeutic use ; MicroRNAs*/MicroRNAs*/MicroRNAs*/genetics

  • Source: Cells [Cells] 2024 May 17; Vol. 13 (10). Date of Electronic Publication: 2024 May 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

Checkpoint Kinase 1 (CHK1) Inhibition Enhances the Sensitivity of Triple-Negative Breast Cancer Cells to Proton Irradiation via Rad51 Downregulation.

  • Authors : Choi C; Department of Radiation Oncology, Samsung Medical Center, Seoul 06351, Korea.; Cho WK

Subjects: Checkpoint Kinase 1/Checkpoint Kinase 1/Checkpoint Kinase 1/*antagonists & inhibitors ; Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/*drug effects ; Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/*radiation effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 Apr 13; Vol. 21 (8). Date of Electronic Publication: 2020 Apr 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression.

  • Authors : Watari A; Laboratories of Bio-Functional Molecular Chemistry, Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan.; Hasegawa M

Subjects: Claudin-5/Claudin-5/Claudin-5/*genetics ; Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/Gene Expression Regulation, Neoplastic/*drug effects ; Intestinal Mucosa/Intestinal Mucosa/Intestinal Mucosa/*physiology

  • Source: PloS one [PLoS One] 2016 Jan 04; Vol. 11 (1), pp. e0145631. Date of Electronic Publication: 2016 Jan 04 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

The Role of Chaperone-Mediated Autophagy in Cell Cycle Control and Its Implications in Cancer.

  • Authors : Andrade-Tomaz M; Departamento de Oncologia Clínica e Experimental, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo 04037-003, SP, Brazil.; de Souza I

Subjects: Gene Expression Regulation, Neoplastic*; Carcinogenesis/Carcinogenesis/Carcinogenesis/*genetics ; Cell Cycle Checkpoints/Cell Cycle Checkpoints/Cell Cycle Checkpoints/*genetics

  • Source: Cells [Cells] 2020 Sep 22; Vol. 9 (9). Date of Electronic Publication: 2020 Sep 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

MBNL2 Regulates DNA Damage Response via Stabilizing p21.

  • Authors : Cai J; State Key Laboratory of Chemical Oncogenomics, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.; Open FIESTA Center, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, China.

Subjects: DNA Damage* ; Gene Expression Regulation, Neoplastic*; Cyclin-Dependent Kinase Inhibitor p21/Cyclin-Dependent Kinase Inhibitor p21/Cyclin-Dependent Kinase Inhibitor p21/*genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 14; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Histone deacetylase inhibitors downregulate checkpoint kinase 1 expression to induce cell death in non-small cell lung cancer cells.

  • Authors : Brazelle W; Thoracic Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.; Kreahling JM

Subjects: Gene Expression Regulation, Enzymologic* ; Gene Expression Regulation, Neoplastic*; Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*enzymology

  • Source: PloS one [PLoS One] 2010 Dec 14; Vol. 5 (12), pp. e14335. Date of Electronic Publication: 2010 Dec 14.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Enhanced Efficacy of Combined Therapy with Checkpoint Kinase 1 Inhibitor and Rucaparib via Regulation of Rad51 Expression in BRCA Wild-Type Epithelial Ovarian Cancer Cells

Subjects: BRCA2 Protein; Ovarian Neoplasms; Indoles

  • Source: Cancer Res Treat

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Academic Journal

CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response.

  • Authors : Bargiela-Iparraguirre J; Dpto.Bioquímica. Fac. Medicina. Instituto de Investigaciones Biomédicas Madrid CSIC-UAM; Madrid, Spain.

Subjects: Chemoradiotherapy* ; Gene Expression Regulation, Enzymologic*/Gene Expression Regulation, Enzymologic*/Gene Expression Regulation, Enzymologic*/drug effects ; Gene Expression Regulation, Enzymologic*/Gene Expression Regulation, Enzymologic*/Gene Expression Regulation, Enzymologic*/radiation effects

  • Source: Scientific reports [Sci Rep] 2016 Feb 12; Vol. 6, pp. 21519. Date of Electronic Publication: 2016 Feb 12.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Claspin - checkpoint adaptor and DNA replication factor.

  • Authors : Smits VAJ; Hospital Universitario de Canarias, Unidad de Investigación, La Laguna, Tenerife, Spain.; Facultad de Medicina, Instituto de Tecnologías Biomédicas, Centro de Investigaciones Biomédicas de Canarias, Universidad de La Laguna, Tenerife, Spain.

Subjects: DNA Replication* ; Gene Expression Regulation, Neoplastic*; Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/Adaptor Proteins, Signal Transducing/*genetics

  • Source: The FEBS journal [FEBS J] 2019 Feb; Vol. 286 (3), pp. 441-455. Date of Electronic Publication: 2018 Jun 29.Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication

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Academic Journal

Identification of candidate biomarkers and pathways associated with SCLC by bioinformatics analysis.

  • Authors : Wen P; Department of Pathophysiology, Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.; Chidanguro T

Subjects: Gene Expression Regulation, Neoplastic* ; Gene Regulatory Networks*; Biomarkers, Tumor/Biomarkers, Tumor/Biomarkers, Tumor/*genetics

  • Source: Molecular medicine reports [Mol Med Rep] 2018 Aug; Vol. 18 (2), pp. 1538-1550. Date of Electronic Publication: 2018 May 29.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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  • 1-10 ل  175 نتائج ل ""CHECKPOINT kinase 1""