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Computational identification of gene over-expression targets for metabolic engineering of taxadiene production.

• Authors : Boghigian BA; Department of Chemical and Biological Engineering, Science and Technology Center, Tufts University, 4 Colby Street, Medford, MA 02155, USA.; Armando J

Subjects: Gene Expression* ; Metabolic Engineering*; Alkenes/Alkenes/Alkenes/*metabolism

• Source: Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2012 Mar; Vol. 93 (5), pp. 2063-73. Date of Electronic Publication: 2011 Nov 30.Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Analysis of heterologous taxadiene production in K- and B-derived Escherichia coli.

• Authors : Boghigian, Brett¹; Salas, Daniel¹; Ajikumar, Parayil²

Subjects: *ANTINEOPLASTIC agents; *ESCHERICHIA coli; *BIOSYNTHESIS

• Source: Applied Microbiology & Biotechnology. Feb2012, Vol. 93 Issue 4, p1651-1661. 11p.

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Engineering Isoprenoid Biosynthesis in Artemisia annua L. for the Production of Taxadiene: A Key Intermediate of Taxol.

• Authors : Li, Meiya^1,2 ; Jiang, Fusheng² ; Yu, Xiangli¹

• Source: BioMed Research International. 2/1/2015, Vol. 2015, p1-8. 8p.

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Analysis of heterologous taxadiene production in K- and B-derived Escherichia coli

• Authors : Parayil Kumaran Ajikumar; Gregory Stephanopoulos; Brett A. Boghigian

Subjects: Heterologous; Gene Expression; Antineoplastic Agents

• Source: Appl Microbiol Biotechnol

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A cDNA Clone for Taxadiene Synthase, the Diterpene Cyclase That Catalyzes the Committed Step of Taxol Biosynthesis

• Authors : Rodney Croteau; Mark R. Wildung

Subjects: DNA, Complementary; Paclitaxel; Molecular Sequence Data

• Source: Journal of Biological Chemistry. 271:9201-9204

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Comparison of elicitor-based effects on metabolic responses of Taxus × media hairy roots in perfluorodecalin-supported two-phase culture system

• Authors : Marta Grech-Baran; Katarzyna Sykłowska-Baranek; Jacek Hennig

Subjects: 0106 biological sciences; 0301 basic medicine; Perfluorodecalin

• Source: Plant Cell Reports

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Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases

• Authors : Golda G. Harris; Lian Duan; Travis A. Pemberton

Subjects: Models, Molecular; 0301 basic medicine; Sesterterpenes

• Source: Biochemistry. 56:2010-2023

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A Cas9-based toolkit to program gene expression in Saccharomyces cerevisiae

• Authors : Maren Wehrs; Gary J. Tong; Rachel Li

Subjects: 0301 basic medicine; Gene Expression; Computational biology

• Source: Nucleic acids research, vol 45, iss 1Apel, AR; D'Espaux, L; Wehrs, M; Sachs, D; Li, RA; Tong, GJ; et al.(2017). A Cas9-based toolkit to program gene expression in

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Effect of initial ammonium concentration on taxoid production and biosynthesis genes expression profile in suspension cultures of Taxus chinensis cells

• Authors : Xin Zhou; Jian-Jiang Zhong

Subjects: Environmental Engineering; Taxane; biology

• Source: Engineering in Life Sciences. 9:261-266

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Taxol biosynthesis: Taxane 13α-hydroxylase is a cytochrome P450-dependent monooxygenase

• Authors : Robert M. Williams; Christopher D. Rithner; Rodney Croteau

Subjects: DNA, Complementary; Paclitaxel; Cytochrome

• Source: Proceedings of the National Academy of Sciences. 98:13595-13600

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