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The Histogenetic Origin of Malignant Cells Predicts Their Susceptibility towards Synthetic Lethality Utilizing the TK.007 System.

• Authors : Pallasch, Fabian Bernhard^1,2 (AUTHOR) ; Freytag, Vera¹ (AUTHOR); Kriegs, Malte^3,4 (AUTHOR)

• Source: Cancers. Jun2024, Vol. 16 Issue 12, p2278. 22p.

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Synthetic Lethality between Cohesin and WNT Signaling Pathways in Diverse Cancer Contexts.

• Authors : Pallotta, Maria Michela¹ (AUTHOR) ; Di Nardo, Maddalena¹ (AUTHOR); Musio, Antonio¹ (AUTHOR)

• Source: Cells (2073-4409). Apr2024, Vol. 13 Issue 7, p608. 17p.

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LRPPRC promotes glycolysis by stabilising LDHA mRNA and its knockdown plus glutamine inhibitor induces synthetic lethality via m6A modification in triple‐negative breast cancer.

• Authors : Yu, Yuanhang^1,2 (AUTHOR); Deng, Huifang¹ (AUTHOR); Wang, Wenwen³ (AUTHOR)

• Source: Clinical & Translational Medicine. Feb2024, Vol. 14 Issue 2, p1-24. 24p.

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Pro-Oxidant Auranofin and Glutathione-Depleting Combination Unveils Synergistic Lethality in Glioblastoma Cells with Aberrant Epidermal Growth Factor Receptor Expression.

• Authors : Martinez-Jaramillo, Elvis^1,2 (AUTHOR) ; Jamali, Fatemeh² (AUTHOR) ; Abdalbari, Farah H.^1,2 (AUTHOR)

• Source: Cancers. Jul2024, Vol. 16 Issue 13, p2319. 29p.

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Mediator subunit MDT-15 promotes expression of propionic acid breakdown genes to prevent embryonic lethality in Caenorhabditis elegans.

• Authors : Ying Shyen Goh, Grace^1,2,3,4; Beigi, Arshia^2,3,5; Junran Yan^1,2,3

• Source: G3: Genes | Genomes | Genetics. Jun2023, Vol. 13 Issue 6, p1-10. 10p.

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Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic β cells resulting in neonatal lethality.

• Authors : Kaur, Gurvinder¹ (AUTHOR); Helmer, Rebecca A.² (AUTHOR); Martinez-Marin, Dalia^2,3 (AUTHOR)

Subjects: *RECEPTOR for advanced glycation end products (RAGE); *DNA repair; *TRANSCRIPTION factors

• Source: PLoS ONE. 8/25/2023, Vol. 18 Issue 8, p1-18. 18p.

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Maternal Gliadin Intake Reduces Oocyte Quality with Chromosomal Aberrations and Increases Embryonic Lethality through Oxidative Stress in a Caenorhabditis elegans Model.

• Authors : Lee, Jae Hyuck¹; Lee, Mijin¹; Min, Hyemin¹

Subjects: *MOTHERS; *BIOLOGICAL models; *GLUTEN

• Source: Nutrients. Dec2022, Vol. 14 Issue 24, p5403. 12p.

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Targeting Histone Epigenetic Modifications and DNA Damage Responses in Synthetic Lethality Strategies in Cancer?

• Authors : Lazo, Pedro A.^1,2 (AUTHOR)

• Source: Cancers. Aug2022, Vol. 14 Issue 16, p4050. 21p.

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Keratinocyte-targeted expression of human laminin γ2 rescues skin blistering and early lethality of laminin γ2 deficient mice.

• Authors : Adair-Kirk TL; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. ; Griffin GL

Subjects: Gene Expression* ; Genes, Lethal*; Blister/Blister/Blister/*genetics

• Source: PloS one [PLoS One] 2012; Vol. 7 (9), pp. e45546. Date of Electronic Publication: 2012 Sep 18.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet

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Aberrant activation of the human sex-determining gene in early embryonic development results in postnatal growth retardation and lethality in mice

• Authors : Kido, Tatsuo; Sun, Zhaoyu; Lau, Yun-Fai Chris

Subjects: Biological Sciences; Biomedical and Clinical Sciences; Genetics

• Source: Scientific Reports. 7(1)

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