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Reduced dynamin-1 levels in neurons lacking MUNC18-1

• Authors : Hanna C. A. Lammertse; Alessandro Moro; Ingrid Saarloos ...

Subjects: Neurons; Dynamin; Munc18 Proteins

• Source: Journal of cell science, 135(22):jcs260132, 1-12. Company of Biologists LtdJournal of Cell Science, 135(22):jcs260132. Company of Biologists LtdLammertse, H C A, Moro, A, Saarloos, I,

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Munc18-1 Is Essential for Neuropeptide Secretion in Neurons

• Authors : Margherita Farina; Matthijs Verhage; Daniël C. Puntman ...

Subjects: Chemistry; General Neuroscience; Vesicle

• Source: J NeurosciPuntman, D C, Arora, S, Farina, M, Toonen, R F & Verhage, M 2021, ' Munc18-1 is essential for neuropeptide secretion in neurons ', Journal of

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Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly

• Authors : Jaeil Shin; Younghun Jung; Sanghwa Lee

Subjects: 0301 basic medicine; Protein Conformation; Science

• Source: Scientific ReportsScientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)

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Munc13-1 MUN domain and Munc18-1 cooperatively chaperone SNARE assembly through a tetrameric complex

• Authors : Yongli Zhang; Huaizhou Jin; James E. Rothman

Subjects: Vesicle fusion; Optical Tweezers; Synaptosomal-Associated Protein 25

• Source: Proc Natl Acad Sci U S A

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Munc18-1 is crucial to overcome the inhibition of synaptic vesicle fusion by αSNAP

• Authors : Karolina P. Stepien; Josep Rizo; Eric A Prinslow

Subjects: 0301 basic medicine; Synaptobrevin; Protein Conformation

• Source: Nature CommunicationsNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)

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The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming

• Authors : Rachel S. Gormal; Andreas Papadopulos; Brett M. Collins ...

Subjects: Models, Molecular; high-density; 0301 basic medicine

• Source: The Journal of Cell Biology

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Munc18-2, but not Munc18-1 or Munc18-3, regulates platelet exocytosis, hemostasis, and thrombosis

• Authors : Roberto Adachi; Keegan Breaux; Rodolfo A. Cardenas

Subjects: 0301 basic medicine; Blood Platelets; Biochemistry

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Munc18-1 catalyzes neuronal SNARE assembly by templating SNARE association

• Authors : Junyi Jiao; Sarah A. Port; Hong Qu

Subjects: 0301 basic medicine; Vesicle-Associated Membrane Protein 2; Structural Biology and Molecular Biophysics

• Source: eLife, Vol 7 (2018)eLife

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The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis

• Authors : Yinghui Liu; Chen Zhang; Daniel R. Gulbranson

Subjects: 0301 basic medicine; Amino Acid Motifs; Syntaxin 1

• Source: The Journal of biological chemistry. 293(47)

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Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle–regulated exocytosis in mast cells

• Authors : Roberto Adachi; Alan R. Burns; Alfredo J. Davalos

Subjects: 0301 basic medicine; Munc18 Proteins; Patch-Clamp Techniques

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