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Subject : enzyme activation

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Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling

Authors : Andy Nguyen; Andrew D. McCulloch; Joan Heller Brown

Subjects: 0301 basic medicine; RHOA; Cultured tumor cells

Source: PLoS BiologyPLoS Biology, Vol 18, Iss 9, p e3000866 (2020)

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Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways

Authors : Yulin Deng; Tuo Zhao; Qin Zhao

Subjects: 0301 basic medicine; RHOA; Integrin

Source: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)Scientific Reports

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RhoA and RhoC are involved in stromal cell-derived factor-1-induced cell migration by regulating F-actin redistribution and assembly

Authors : Xiaoguang Wang; Dan Wei; Jixian Luo

Subjects: 0301 basic medicine; RHOA; Stromal cell

Source: Molecular and Cellular Biochemistry. 436:13-21

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Characterization of the activation of small GTPases by their GEFs on membranes using artificial membrane tethering

Authors : François Peurois; Yann Ferrandez; Ilham Ladid

Subjects: rac1 GTP-Binding Protein; rho GTP-Binding Proteins; 0301 basic medicine

Source: Biochemical Journal. 474:1259-1272

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α-TEA inhibits the growth and motility of human colon cancer cells via targeting RhoA/ROCK signaling

Authors : Jialin Yao; Peng Gao; Zhaozhu Li

Subjects: 0301 basic medicine; Cancer Research; RHOA

Source: Molecular Medicine Reports

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Cigarette smoke induces endoplasmic reticulum stress and suppresses efferocytosis through the activation of RhoA

Authors : Takeshi Tanaka; Masahiro Takaki; Minh Nhat Le

Subjects: Indoles; RHOA; Thapsigargin

Source: Scientific ReportsScientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)

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KMUP-1 Attenuates Endothelin-1-Induced Cardiomyocyte Hypertrophy through Activation of Heme Oxygenase-1 and Suppression of the Akt/GSK-3β, Calcineurin/NFATc4 and RhoA/ROCK Pathways

Authors : You-Ting Chen; Ing-Jun Chen; Jwu-Lai Yeh

Subjects: MAPK/ERK pathway; medicine.medical_specialty; RHOA

Source: Molecules, Vol 20, Iss 6, Pp 10435-10449 (2015)MoleculesVolume 20Issue 6Pages 10435-10449

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Type II cGMP-dependent protein kinase inhibits RhoA activation in gastric cancer cells

Authors : Yongchang Chen; Yueying Li; Ying Wang

Subjects: Cancer Research; RHOA; Stress fiber

Source: Molecular Medicine Reports. 9:1444-1452

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PKCδ as a regulator for TGF-β-stimulated connective tissue growth factor production in human hepatocarcinoma (HepG2) cells

Authors : Jeong Han Kang; Su-Jin Lee; Soo Young Choi

Subjects: medicine.medical_specialty; RHOA; medicine.medical_treatment

Source: Biochemical Journal. 456:109-118

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Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells

Authors : Nathalie R. Reinhard; Eloise C. Anthony; Peter L. Hordijk ...

Subjects: 0301 basic medicine; Models, Molecular; RHOA

Source: Scientific ReportsScientific reports, 6. Nature Publishing GroupScientific Reports, 6:25502. Nature Publishing GroupScientific Reports, 6. Nature Publishing GroupReinhard, N R,

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