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Academic Journal

Molecular mechanism of dynein-dynactin complex assembly by LIS1.

  • Authors : Singh K; MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, UK.; Lau CK

Subjects: Dynactin Complex*/Dynactin Complex*/Dynactin Complex*/chemistry ; Dynactin Complex*/Dynactin Complex*/Dynactin Complex*/genetics ; Dynactin Complex*/Dynactin Complex*/Dynactin Complex*/metabolism

  • Source: Science (New York, N.Y.) [Science] 2024 Mar 29; Vol. 383 (6690), pp. eadk8544. Date of Electronic Publication: 2024 Mar 29.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Dysregulation of stress granule dynamics by DCTN1 deficiency exacerbates TDP-43 pathology in Drosophila models of ALS/FTD.

  • Authors : Ueda T; Department of Neurology, Faculty of Medicine, Kindai University, 377-2 Ohnohigashi, Osakasayama, Osaka, 589-8511, Japan.; Department of Neurotherapeutics, Osaka University Graduate School of Medicine, Osaka, 565-0871, Japan.

Subjects: Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/Amyotrophic Lateral Sclerosis*/pathology ; DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/genetics ; DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/metabolism

  • Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Feb 04; Vol. 12 (1), pp. 20. Date of Electronic Publication: 2024 Feb 04.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Academic Journal

Cryo-EM reveals the complex architecture of dynactin's shoulder region and pointed end.

  • Authors : Lau CK; Structural Studies Division, MRC Laboratory of Molecular Biology, Cambridge, UK.; O'Reilly FJ

Subjects: Dynactin Complex/Dynactin Complex/Dynactin Complex/*chemistry; Cryoelectron Microscopy ; Dynactin Complex/Dynactin Complex/Dynactin Complex/metabolism

  • Source: The EMBO journal [EMBO J] 2021 Apr 15; Vol. 40 (8), pp. e106164. Date of Electronic Publication: 2021 Mar 18.Publisher: Wiley Blackwell Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

DCTN1 Binds to TDP-43 and Regulates TDP-43 Aggregation.

  • Authors : Deshimaru M; Department of Neurology, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.; Department of Neuropharmacology, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka 814-0180, Japan.

Subjects: Protein Aggregates*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Dynactin Complex/Dynactin Complex/Dynactin Complex/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 13; Vol. 22 (8). Date of Electronic Publication: 2021 Apr 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Autophagy and Ubiquitin-Proteasome System Coordinate to Regulate the Protein Quality Control of Neurodegenerative Disease-Associated DCTN1.

  • Authors : Wang N; Jiangsu Key Laboratory of Neuropsychiatric Diseases and College of Pharmaceutical Sciences, |Soochow University, Suzhou, 215123, Jiangsu, China.; Ma Q

Subjects: Proteolysis*; Autophagy/Autophagy/Autophagy/*physiology ; Dynactin Complex/Dynactin Complex/Dynactin Complex/*physiology

  • Source: Neurotoxicity research [Neurotox Res] 2020 Jan; Vol. 37 (1), pp. 48-57. Date of Electronic Publication: 2019 Oct 25.Publisher: Springer Country of Publication: United States NLM ID: 100929017 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

N4BP2L1 interacts with dynactin and contributes to GLUT4 trafficking and glucose uptake in adipocytes.

  • Authors : Watanabe K; Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.; Matsumoto A

Subjects: Adipocytes/Adipocytes/Adipocytes/*metabolism ; Carrier Proteins/Carrier Proteins/Carrier Proteins/*metabolism ; Dynactin Complex/Dynactin Complex/Dynactin Complex/*metabolism

  • Source: Journal of diabetes investigation [J Diabetes Investig] 2021 Nov; Vol. 12 (11), pp. 1958-1966. Date of Electronic Publication: 2021 Jul 17.Publisher: Asian Association for the Study of Diabetes and Blackwell Pub. Asia Country of Publication: Japan NLM ID: 101520702 Publication Model:

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Academic Journal

Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150 glued .

  • Authors : Suh BK; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Republic of Korea.; Lee SA

Subjects: Axons/Axons/Axons/*metabolism ; Dynactin Complex/Dynactin Complex/Dynactin Complex/*metabolism ; Dysbindin/Dysbindin/Dysbindin/*metabolism

  • Source: Molecular brain [Mol Brain] 2021 Jan 18; Vol. 14 (1), pp. 14. Date of Electronic Publication: 2021 Jan 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101468876 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-6606

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Academic Journal

Genetics of Progressive Supranuclear Palsy: A Review.

  • Authors : Wen Y; Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, PR China.; Zhou Y

Subjects: Dynactin Complex/Dynactin Complex/Dynactin Complex/*genetics ; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/*genetics ; Supranuclear Palsy, Progressive/Supranuclear Palsy, Progressive/Supranuclear Palsy, Progressive/*genetics

  • Source: Journal of Parkinson's disease [J Parkinsons Dis] 2021; Vol. 11 (1), pp. 93-105.Publisher: IOS Press Country of Publication: Netherlands NLM ID: 101567362 Publication Model: Print Cited Medium: Internet ISSN: 1877-718X

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Academic Journal

Perry syndrome: a case of atypical parkinsonism with confirmed DCTN1 mutation.

  • Authors : McManus EJ; Basic Trainee/Neurology Registrar, Waikato General Hospital, Hamilton, Waikato.; Poke G

Subjects: Hypoventilation*/Hypoventilation*/Hypoventilation*/diagnosis ; Hypoventilation*/Hypoventilation*/Hypoventilation*/genetics ; Hypoventilation*/Hypoventilation*/Hypoventilation*/physiopathology Perry Syndrome

  • Source: The New Zealand medical journal [N Z Med J] 2020 Apr 24; Vol. 133 (1513), pp. 116-118. Date of Electronic Publication: 2020 Apr 24.Publisher: Pasifika Medical Association Group Country of Publication: New Zealand NLM ID: 0401067 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

New phenotype of DCTN1-related spectrum: early-onset dHMN plus congenital foot deformity.

  • Authors : Tian WT; Department of Neurology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Liu LH

Subjects: Dynactin Complex/Dynactin Complex/Dynactin Complex/*genetics ; Foot Deformities, Congenital/Foot Deformities, Congenital/Foot Deformities, Congenital/*genetics ; Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/Muscular Atrophy, Spinal/*genetics

  • Source: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2020 Feb; Vol. 7 (2), pp. 200-209. Date of Electronic Publication: 2020 Feb 05.Publisher: Wiley Periodicals, Inc on behalf of American Neurological Association Country of Publication: United States NLM ID: 101623278 Publication Model:

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