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  • 1-10 ل  84 نتائج ل ""Myeloid Cell Leukemia Sequence 1 Protein""

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Subject : drug resistance, neoplasm
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Academic Journal

Low BCL-xL expression in triple-negative breast cancer cells favors chemotherapy efficacy, and this effect is limited by cancer-associated fibroblasts.

  • Authors : Nocquet L; INSERM, CNRS, CRCI2NA, Université de Nantes, 44000, Nantes, France.; Equipe Labellisée LIGUE Contre le Cancer, Paris, France.

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Jun 19; Vol. 14 (1), pp. 14177. Date of Electronic Publication: 2024 Jun 19.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

CD157 signaling promotes survival of acute myeloid leukemia cells and modulates sensitivity to cytarabine through regulation of anti-apoptotic Mcl-1.

  • Authors : Yakymiv Y; Laboratory of Immunogenetics, Department of Medical Sciences, University of Torino, Via Santena 19, 10126, Torino, Italy.; Augeri S

Subjects: Drug Resistance, Neoplasm*; ADP-ribosyl Cyclase/ADP-ribosyl Cyclase/ADP-ribosyl Cyclase/*metabolism ; Antigens, CD/Antigens, CD/Antigens, CD/*metabolism

  • Source: Scientific reports [Sci Rep] 2021 Oct 27; Vol. 11 (1), pp. 21230. Date of Electronic Publication: 2021 Oct 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Heterogeneous Pattern of Dependence on Anti-Apoptotic BCL-2 Family Proteins upon CHOP Treatment in Diffuse Large B-Cell Lymphoma.

  • Authors : de Jong MRW; Department of Hematology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.; Langendonk M

Subjects: Gene Expression Regulation, Neoplastic*; Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/Antineoplastic Combined Chemotherapy Protocols/*therapeutic use ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 Nov 30; Vol. 20 (23). Date of Electronic Publication: 2019 Nov 30.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Enhancement of chemosensitivity by simultaneously silencing of Mcl-1 and Survivin genes using small interfering RNA in human myelomonocytic leukaemia.

  • Authors : Jafarlou M; a Immunology Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.; b Department of Human Anatomy, Faculty of Medicine and Health Sciences, UPM , Selangor , Malaysia.

Subjects: Apoptosis* ; Drug Resistance, Neoplasm* ; Gene Silencing*

  • Source: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2018 Dec; Vol. 46 (8), pp. 1792-1798. Date of Electronic Publication: 2017 Nov 07.Publisher: Taylor & Francis Country of Publication: England NLM ID: 101594777 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

ER+ Breast Cancer Strongly Depends on MCL-1 and BCL-xL Anti-Apoptotic Proteins.

  • Authors : Alcon C; Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST), 08028 Barcelona, Spain.; Gómez Tejeda Zañudo J

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Apoptosis/Apoptosis/Apoptosis/*drug effects ; Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*pharmacology

  • Source: Cells [Cells] 2021 Jul 02; Vol. 10 (7). Date of Electronic Publication: 2021 Jul 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

BIRC6 mediates imatinib resistance independently of Mcl-1.

  • Authors : Okumu DO; Department of Pharmacology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America.; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, United States of America.

Subjects: Apoptosis*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*toxicity ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics

  • Source: PloS one [PLoS One] 2017 May 16; Vol. 12 (5), pp. e0177871. Date of Electronic Publication: 2017 May 16 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Trifolium Flavonoids Overcome Gefitinib Resistance of Non-Small-Cell Lung Cancer Cell by Suppressing ERK and STAT3 Signaling Pathways.

  • Authors : Wu Z; Jinhua Municipal Central Hospital, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, China.; Xu B

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*drug effects ; Epithelial Cells/Epithelial Cells/Epithelial Cells/*drug effects

  • Source: BioMed research international [Biomed Res Int] 2020 Oct 22; Vol. 2020, pp. 2491304. Date of Electronic Publication: 2020 Oct 22 (Print Publication: 2020).Publisher: Hindawi Pub. Co Country of Publication: United States NLM ID: 101600173 Publication Model: eCollection Cited Medium: Internet ISSN:

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Academic Journal

Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia.

  • Authors : Lin KH; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC 27710, USA.; Winter PS

Subjects: Drug Resistance, Neoplasm*; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/Bridged Bicyclo Compounds, Heterocyclic/*pharmacology

  • Source: Scientific reports [Sci Rep] 2016 Jun 10; Vol. 6, pp. 27696. Date of Electronic Publication: 2016 Jun 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

MUC1-C Stabilizes MCL-1 in the Oxidative Stress Response of Triple-Negative Breast Cancer Cells to BCL-2 Inhibitors.

  • Authors : Hiraki M; Dana-Farber Cancer Institute Harvard Medical School Boston, MA 02215, USA.; Suzuki Y

Subjects: Aniline Compounds/Aniline Compounds/Aniline Compounds/*pharmacology ; Biphenyl Compounds/Biphenyl Compounds/Biphenyl Compounds/*pharmacology ; Breast Neoplasms/Breast Neoplasms/Breast Neoplasms/*metabolism

  • Source: Scientific reports [Sci Rep] 2016 May 24; Vol. 6, pp. 26643. Date of Electronic Publication: 2016 May 24.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Loss of FBXW7-mediated degradation of BRAF elicits resistance to BET inhibitors in adult T cell leukemia cells.

  • Authors : Yeh CH; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA.; Bellon M

Subjects: Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/Drug Resistance, Neoplasm/*genetics ; F-Box-WD Repeat-Containing Protein 7/F-Box-WD Repeat-Containing Protein 7/F-Box-WD Repeat-Containing Protein 7/*genetics ; Leukemia-Lymphoma, Adult T-Cell/Leukemia-Lymphoma, Adult T-Cell/Leukemia-Lymphoma, Adult T-Cell/*genetics

  • Source: Molecular cancer [Mol Cancer] 2020 Sep 09; Vol. 19 (1), pp. 139. Date of Electronic Publication: 2020 Sep 09.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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  • 1-10 ل  84 نتائج ل ""Myeloid Cell Leukemia Sequence 1 Protein""