نتائج البحث

Structural and free energy landscape analysis for the discovery of antiviral compounds targeting the cap-binding domain of influenza polymerase PB2.

• Authors : Abouzied AS; Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, 81442, Hail, Saudi Arabia.; Department of Pharmaceutical Chemistry, Egyptian Drug Authority, Giza, Egypt.

Subjects: Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/pharmacology ; Antiviral Agents*/Antiviral Agents*/Antiviral Agents*/chemistry ; Molecular Dynamics Simulation*

• Source: Scientific reports [Sci Rep] 2024 Oct 25; Vol. 14 (1), pp. 25441. Date of Electronic Publication: 2024 Oct 25.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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含苯氧甲基、氯甲基的十元、十二元及十六元氮杂 内酯化合物的合成及抑菌活性.

• Authors : 王思敏¹ ; 宁磊¹; 张莉¹

• Source: Chinese Journal of Pesticide Science / Nongyaoxue Xuebao. Oct2024, Vol. 26 Issue 5, p870-882. 13p.

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Free Radical Production Induced by Nitroimidazole Compounds Lead to Cell Death in Leishmania infantum Amastigotes.

• Authors : Andrés-Rodríguez, Julia¹ (AUTHOR) ; González-Montero, María-Cristina¹ (AUTHOR) ; García-Fernández, Nerea¹ (AUTHOR)

Subjects: *AFRICAN trypanosomiasis; *NEGLECTED diseases; *DRUG discovery

• Source: Molecules. Sep2024, Vol. 29 Issue 17, p4041. 14p.

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Recent Advances: Heterocycles in Drugs and Drug Discovery.

• Authors : Pibiri I; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, 90128 Palermo, Italy.

Subjects: Drug Discovery*/Drug Discovery*/Drug Discovery*/methods ; Heterocyclic Compounds*/Heterocyclic Compounds*/Heterocyclic Compounds*/pharmacology ; Heterocyclic Compounds*/Heterocyclic Compounds*/Heterocyclic Compounds*/chemistry

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 31; Vol. 25 (17). Date of Electronic Publication: 2024 Aug 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Bioactive Compounds from Natural Sources: Discovery, Evaluation, and Applications.

• Authors : Liu T; Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances, School of Basic Medical Sciences, Guangdong Pharmaceutical University, Guangzhou 510006, China.; Chen X

Subjects: Biological Products*/Biological Products*/Biological Products*/chemistry ; Biological Products*/Biological Products*/Biological Products*/pharmacology ; Drug Discovery*

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jul 05; Vol. 29 (13). Date of Electronic Publication: 2024 Jul 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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De Novo Generation and Identification of Novel Compounds with Drug Efficacy Based on Machine Learning.

• Authors : He D; College of Information Science and Engineering, State Key Laboratory of Synthetical Automation for Process Industries, Northeastern University, Shenyang, 110819, China.; Liu Q

Subjects: Machine Learning* ; Drug Discovery*/Drug Discovery*/Drug Discovery*/methods; Proteins

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Mar; Vol. 11 (11), pp. e2307245. Date of Electronic Publication: 2024 Jan 10.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Hoslundia opposita vahl; a potential source of bioactive compounds with antioxidant and antibiofilm activity for wound healing.

• Authors : Namuga, Catherine^1,2 (AUTHOR) ; Muwonge, Haruna³ (AUTHOR); Nasifu, Kerebba⁴ (AUTHOR)

Subjects: *BACTERIAL disease prevention; *WOUND healing; *BIOFILMSUGANDA

• Source: BMC Complementary Medicine & Therapies. 6/17/2024, Vol. 24 Issue 1, p1-16. 16p.

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Diversity-Orientated Synthesis and Biological Properties of Compounds Based on the N -Phenylquinoneimine Scaffold.

• Authors : Adesina A; Department of Chemistry, Federal University of Agriculture, Abeokuta 111101, Nigeria.; Skouta R

Subjects: Chemistry, Pharmaceutical* ; Drug Discovery*

• Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 03; Vol. 29 (1). Date of Electronic Publication: 2024 Jan 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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In Silico Comparison of Bioactive Compounds Characterized from Azadirachta indica with an FDA-Approved Drug against Schistosomal Agents: New Insight into Schistosomiasis Treatment.

• Authors : Oyinloye, Babatunji Emmanuel^1,2,3 (AUTHOR) ; Shamaki, David Ezekiel^1,2 (AUTHOR); Agbebi, Emmanuel Ayodeji^3,4 (AUTHOR)

Subjects: *SCHISTOSOMIASIS; *DIHYDROOROTATE dehydrogenase; *BIOACTIVE compoundsSUB-Saharan Africa

• Source: Molecules. May2024, Vol. 29 Issue 9, p1909. 22p.

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Meta-learning for transformer-based prediction of potent compounds.

• Authors : Chen H; Department of Life Science Informatics and Data Science, B-IT, Lamarr Institute for Machine Learning and Artificial Intelligence, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Friedrich-Hirzebruch-Allee 5/6, 53115, Bonn, Germany.; Bajorath J

Subjects: Drug Discovery* ; Electric Power Supplies*; Machine Learning

• Source: Scientific reports [Sci Rep] 2023 Sep 26; Vol. 13 (1), pp. 16145. Date of Electronic Publication: 2023 Sep 26.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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