نتائج البحث

Dichloroacetate and PX-478 exhibit strong synergistic effects in a various number of cancer cell lines

• Authors : Parczyk, Jonas; Ruhnau, Jérôme; Pelz, Carsten

Subjects: HIF-1α inhibition; Drug combination; Cell Line

• Source: http://lobid.org/resources/99370673697106441#!, 21(1):481.

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Pharmacological inhibition of thioredoxin reductase increases insulin secretion and diminishes beta cell viability

• Authors : Brüning, Dennis; Hatlapatka, Kathrin; Lier-Glaubitz, Verena

Subjects: Dose-Response Relationship; Drug [MeSH]; Female [MeSH]

• Source: http://lobid.org/resources/99370679168606441#!, 394(6):1133-1142.

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A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy

• Authors : Fischer, Nicolas; Seo, Ean-Jeong; Abdelfatah, Sara

Subjects: Dose-Response Relationship; Drug [MeSH]; Molecular Docking Simulation [MeSH]

• Source: http://lobid.org/resources/99370674913906441#!, 39(4):914-927.

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Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction

• Authors : Jae Hyun Kim; Kilsoo Jung; Chulho Lee

Subjects: Cell Line; Cell Survival / drug effects; Dose-Response Relationship

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Synthesis of novel 1H-Pyrazolo[3,4-b]pyridine derivatives as DYRK 1A/1B inhibitors

• Authors : Areum Park; Jieon Hwang; Joo-Youn Lee

Subjects: Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology

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Design, Optimization, and Structural Characterization of an Apoptosis-Inducing Factor Peptide Targeting Human Cyclophilin A to Inhibit Apoptosis Inducing Factor-Mediated Cell Death

• Authors : Russo, Luigi; Mascanzoni, Fabiola; Farina, Biancamaria

Subjects: Animals; Apoptosis/drug effects; Apoptosis Inducing Factor/chemical synthesis

• Source: Russo , L , Mascanzoni , F , Farina , B , Dolga , A M , Monti , A , Caporale , A , Culmsee , C , Fattorusso , R , Ruvo , M & Doti , N 2021 , ' Design, Optimization, and Structural Characterization of

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Modeling chemotherapy induced neurotoxicity with human induced pluripotent stem cell (iPSC) -derived sensory neurons.

• Authors : Schinke, Christian; Fernandez Vallone, Valeria; Endres, Matthias

Subjects: info:eu-repo/classification/ddc/570; Antineoplastic Agents: toxicity; Axons: drug effectsDE

• Source: Neurobiology of disease 155, 105391 (2021). doi:10.1016/j.nbd.2021.105391

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Dedifferentiated Schwann cells secrete progranulin that enhances the survival and axon growth of motor neurons

• Authors : Sujin Hyung; Sun�륦young Im; Bo Yoon Lee

Subjects: Animals; Axons/drug effects; Axons/pathology

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Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition

• Authors : Chen, Mengqian; Li, Jing; Liang, Jiaxin

Subjects: CDK19; CDK8; STAT1 serine phosphorylation

• Source: Faculty Publications

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Oleuropein derivatives from olive fruit extracts reduce α-synuclein fibrillation and oligomer toxicity

• Authors : Mohammad-Beigi, Hossein; Aliakbari, Farhang; Sahin, Cagla

Subjects: synuclein (-synuclein); ADHERENCE; AGGREGATION

• Source: Mohammad-Beigi , H , Aliakbari , F , Sahin , C , Lomax , C , Tawfike , A , P. Schafer , N , Amiri-Nowdijeh , A , Eskandari , H , Møller , I M , Hosseini-Mazinani , M , Christiansen , G , Ward , J L ,

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