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Academic Journal

Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation.

Authors : Debaize L; Univ Rennes, CNRS, IGDR (Institut de Génétique et Développement de Rennes) - UMR 6290, F-35000 Rennes, France.; Jakobczyk H

Subjects: Enhancer Elements, Genetic* ; Gene Expression Regulation, Leukemic*; Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/*genetics

Source: Nucleic acids research [Nucleic Acids Res] 2018 Nov 30; Vol. 46 (21), pp. 11214-11228.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Pleomorphic adenoma gene 1 mediates the role of karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma.

Authors : Hu ZY; Yuan SX; Yang Y

Subjects: Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*metabolism ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Liver Neoplasms/Liver Neoplasms/Liver Neoplasms/*metabolism

Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2014 Jul 25; Vol. 33, pp. 61. Date of Electronic Publication: 2014 Jul 25.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Academic Journal

Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.

Authors : Maicas M; Laboratory of Genetics, Division of Oncology, CIMA, University of Navarra, Pamplona, Spain.; Vázquez I

Subjects: Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics ; Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*genetics

Source: Oncogene [Oncogene] 2013 Apr 18; Vol. 32 (16), pp. 2069-78. Date of Electronic Publication: 2012 Jun 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1.

Authors : Feld C; Institute of Molecular Biology and Tumor Research (IMT), School of Medicine, Philipps University Marburg, Hans-Meerwein-Str. 2, 35043 Marburg, Germany.; Department of Internal Medicine and Hematology, Oncology and Immunology, Philipps University Marburg, University Hospital Giessen and Marburg, Baldingerstr., 35043 Marburg, Germany.

Subjects: Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/Core Binding Factor Alpha 2 Subunit/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/Leukemia, Myeloid, Acute/*genetics

Source: Nucleic acids research [Nucleic Acids Res] 2018 Apr 20; Vol. 46 (7), pp. 3412-3428.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.

Authors : Dunne J; Cancer Research UK Medical Oncology Laboratory, Barts and the London School of Medicine, London, UK.; Cullmann C

Subjects: Cell Proliferation* ; Chromosomes, Human, Pair 21* ; Chromosomes, Human, Pair 8*

Source: Oncogene [Oncogene] 2006 Oct 05; Vol. 25 (45), pp. 6067-78. Date of Electronic Publication: 2006 May 01.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Print ISSN:

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Academic Journal

Anomalous interaction of Sp1 and specific binding of an E-box-binding protein with the regulatory elements of the Na,K-ATPase alpha 2 subunit gene promoter.

Authors : Ikeda K; Department of Biology, Jichi Medical School, Tochigi, Japan.; Nagano K

Subjects: Promoter Regions, Genetic*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Sodium-Potassium-Exchanging ATPase/Sodium-Potassium-Exchanging ATPase/Sodium-Potassium-Exchanging ATPase/*genetics

Source: European journal of biochemistry [Eur J Biochem] 1993 Nov 15; Vol. 218 (1), pp. 195-204.Publisher: Blackwell Science Ltd. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 0107600 Publication Model:

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Academic Journal

RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study.

Authors : Shen L; Department of Hematology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, China. .; Zhu J

Source: BMC cancer [BMC Cancer] 2015 Dec 16; Vol. 15, pp. 970. Date of Electronic Publication: 2015 Dec 16.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22).

Authors : Yao H; Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, The First Affiliated Hospital of Soochow University, Suzhou, P.R. China. .; Pan J

Subjects: Chromosomes, Human, Pair 21* ; Chromosomes, Human, Pair 5* ; Transcriptome*

Source: Molecular cancer [Mol Cancer] 2015 Apr 11; Vol. 14, pp. 81. Date of Electronic Publication: 2015 Apr 11.Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598

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Academic Journal

Synergistic requirement of orphan nonamer-like elements and DNA bending enhanced by HMGB1 for RAG-mediated nicking at cryptic 12-RSS but not authentic 12-RSS.

Authors : Numata M; Department of Infection Biology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.; Nagata K

Subjects: V(D)J Recombination*; DNA/DNA/DNA/*metabolism ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism

Source: Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 2011 Aug; Vol. 16 (8), pp. 879-95. Date of Electronic Publication: 2011 Jul 11.Publisher: Blackwell Science Ltd Country of Publication: England NLM ID: 9607379 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Inhibition of DNA topoisomerase II with etoposide induces association of DNA topoisomerase II alpha, DNA topoisomerase II beta, and nucleolin with BCR 2 of the ETO gene.

Authors : Rubtsov MA; Department of Molecular Biology, Faculty of Biology, Moscow State University, Moscow, 119991 Russia.; Razin SV

Subjects: Topoisomerase II Inhibitors*; Antigens, Neoplasm/Antigens, Neoplasm/Antigens, Neoplasm/*metabolism ; DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/DNA Topoisomerases, Type II/*metabolism

Source: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2008 Nov-Dec; Vol. 423, pp. 334-6.Publisher: Pleiades Publishing Country of Publication: United States NLM ID: 101126895 Publication Model: Print Cited Medium: Print ISSN:

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نتائج البحث

فلترة النتائج

Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation.

Pleomorphic adenoma gene 1 mediates the role of karyopherin alpha 2 and has prognostic significance in hepatocellular carcinoma.

Functional characterization of the promoter region of the human EVI1 gene in acute myeloid leukemia: RUNX1 and ELK1 directly regulate its transcription.

Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1.

siRNA-mediated AML1/MTG8 depletion affects differentiation and proliferation-associated gene expression in t(8;21)-positive cell lines and primary AML blasts.

Anomalous interaction of Sp1 and specific binding of an E-box-binding protein with the regulatory elements of the Na,K-ATPase alpha 2 subunit gene promoter.

RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study.

Transcriptome sequencing reveals CHD1 as a novel fusion partner of RUNX1 in acute myeloid leukemia with t(5;21)(q21;q22).

Synergistic requirement of orphan nonamer-like elements and DNA bending enhanced by HMGB1 for RAG-mediated nicking at cryptic 12-RSS but not authentic 12-RSS.

Inhibition of DNA topoisomerase II with etoposide induces association of DNA topoisomerase II alpha, DNA topoisomerase II beta, and nucleolin with BCR 2 of the ETO gene.

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