نتائج البحث

Polyubiquitinated PCNA triggers SLX4-mediated break-induced replication in alternative lengthening of telomeres (ALT) cancer cells.

• Authors : Kim S; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Korea.; Department of Biological Sciences, College of Information-Bio Convergence Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Korea.

Subjects: Telomere Homeostasis*/Telomere Homeostasis*/Telomere Homeostasis*/genetics ; Proliferating Cell Nuclear Antigen*/Proliferating Cell Nuclear Antigen*/Proliferating Cell Nuclear Antigen*/metabolism ; Proliferating Cell Nuclear Antigen*/Proliferating Cell Nuclear Antigen*/Proliferating Cell Nuclear Antigen*/genetics

• Source: Nucleic acids research [Nucleic Acids Res] 2024 Oct 28; Vol. 52 (19), pp. 11785-11805.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Epithelial-to-mesenchymal transition and NF-kB pathways are promoted by a mutant form of DDB2, unable to bind PCNA, in UV-damaged human cells.

• Authors : Perucca P; Dipartimento di Medicina molecolare, Unità di Immunologia e Patologia generale, Università degli Studi di Pavia, Pavia, Italy.; Bassi E

Subjects: Epithelial-Mesenchymal Transition* ; DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/metabolism ; DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/genetics

• Source: BMC cancer [BMC Cancer] 2024 May 21; Vol. 24 (1), pp. 616. Date of Electronic Publication: 2024 May 21.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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A RAD18-UBC13-PALB2-RNF168 axis mediates replication fork recovery in BRCA1-deficient cancer cells.

• Authors : Cybulla E; Division of Oncology, Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO 63104, USA.

Subjects: Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/metabolism ; Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/Ubiquitin-Protein Ligases*/genetics ; DNA Replication*

• Source: Nucleic acids research [Nucleic Acids Res] 2024 Aug 27; Vol. 52 (15), pp. 8861-8879.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus.

• Authors : Vandborg, Bethiney C.^1,2 (AUTHOR) ; Horsfall, Aimee J.^1,3 (AUTHOR) ; Pederick, Jordan L.^1,2 (AUTHOR)

• Source: Journal of Fungi. Nov2023, Vol. 9 Issue 11, p1098. 16p.

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Helicase-Like Transcription Factor HLTF and E3 Ubiquitin Ligase SHPRH Confer DNA Damage Tolerance through Direct Interactions with Proliferating Cell Nuclear Antigen (PCNA).

• Authors : Seelinger M; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology NTNU, N-7491 Trondheim, Norway.; Otterlei M

Subjects: DNA Damage/DNA Damage/DNA Damage/*physiology ; DNA Helicases/DNA Helicases/DNA Helicases/*metabolism ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism

• Source: International journal of molecular sciences [Int J Mol Sci] 2020 Jan 21; Vol. 21 (3). Date of Electronic Publication: 2020 Jan 21.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10.

• Authors : Ouyang, Yujing¹ (AUTHOR); Al-Amodi, Amani¹ (AUTHOR); Tehseen, Muhammad¹ (AUTHOR)

Subjects: *PROLIFERATING cell nuclear antigen; *SV40 (Virus); *DNA primers

• Source: Nucleic Acids Research. 8/27/2024, Vol. 52 Issue 15, p8880-8896. 17p.

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Distinct Motifs in ATAD5 C-Terminal Domain Modulate PCNA Unloading Process.

• Authors : Ryu E; Center for Genomic Integrity, Institute for Basic Science, Ulsan 44919, Korea.; Department of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, Korea.

Subjects: DNA Replication* ; DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/metabolism; DNA/DNA/DNA/metabolism

• Source: Cells [Cells] 2022 Jun 03; Vol. 11 (11). Date of Electronic Publication: 2022 Jun 03.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway.

• Authors : Masuda Y; Department of Genome Dynamics, Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.; Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

Subjects: DNA Repair* ; Protein Processing, Post-Translational*; DNA/DNA/DNA/*genetics

• Source: Nucleic acids research [Nucleic Acids Res] 2018 Nov 30; Vol. 46 (21), pp. 11340-11356.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Simultaneous dual-channel imaging to quantify interdependent protein recruitment to laser-induced DNA damage sites.

• Authors : Garbrecht J; a Department of Biochemistry, Max F. Perutz Laboratories , University of Vienna, Vienna Biocenter (VBC) , Vienna , Austria.; Hornegger H

Subjects: DNA Damage* ; Lasers* ; Optical Imaging*

• Source: Nucleus (Austin, Tex.) [Nucleus] 2018; Vol. 9 (1), pp. 474-491.Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101518322 Publication Model: Print Cited Medium: Internet ISSN:

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Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications.

• Authors : Ivanov I; Department of Chemistry and Biochemistry, Howard Hughes Medical Institute and Center for Theoretical Biological Physics, University of California-San Diego, 9500 Gilman Drive La Jolla, CA 92093-0365, USA. ; Chapados BR

Subjects: DNA/DNA/DNA/*chemistry ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*chemistry ; Proliferating Cell Nuclear Antigen/Proliferating Cell Nuclear Antigen/Proliferating Cell Nuclear Antigen/*chemistry

• Source: Nucleic acids research [Nucleic Acids Res] 2006; Vol. 34 (20), pp. 6023-33. Date of Electronic Publication: 2006 Oct 27.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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