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Academic Journal

RNF8 promotes efficient DSB repair by inhibiting the pro-apoptotic activity of p53 through regulating the function of Tip60.

  • Authors : Chen H; The Key Laboratory of Molecular Epigenetics of Ministry of Education, Institute of Genetics and Cytology, Northeast Normal University, Changchun, Jilin, China.; Shan J

Subjects: DNA Breaks, Double-Stranded* ; DNA Repair*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism

  • Source: Cell proliferation [Cell Prolif] 2020 Mar; Vol. 53 (3), pp. e12780. Date of Electronic Publication: 2020 Feb 07.Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications

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Academic Journal

Phosphorylation of Ku dictates DNA double-strand break (DSB) repair pathway choice in S phase.

  • Authors : Lee KJ; Division of Molecular Radiation Biology, Department of Radiation Oncology, University of Texas Southwestern Medical Center, 2201 Inwood Rd, Dallas, Texas 75390, USA.; Saha J

Subjects: DNA Breaks, Double-Stranded*; Antigens, Nuclear/Antigens, Nuclear/Antigens, Nuclear/*genetics ; DNA End-Joining Repair/DNA End-Joining Repair/DNA End-Joining Repair/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2016 Feb 29; Vol. 44 (4), pp. 1732-45. Date of Electronic Publication: 2015 Dec 27.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

RAG2 mutants alter DSB repair pathway choice in vivo and illuminate the nature of 'alternative NHEJ'.

  • Authors : Gigi V; Department of Pathology and Laboratory Medicine and Abramson Family Cancer Research Institute, Raymond and Ruth Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Lewis S

Subjects: DNA Breaks, Double-Stranded* ; DNA End-Joining Repair*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2014 Jun; Vol. 42 (10), pp. 6352-64. Date of Electronic Publication: 2014 Apr 20.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

53BP1 regulates DSB repair using Rif1 to control 5' end resection.

Subjects: DNA Breaks, Double-Stranded* ; DNA Repair*; Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/*metabolism

  • Source: Science (New York, N.Y.) [Science] 2013 Feb 08; Vol. 339 (6120), pp. 700-4. Date of Electronic Publication: 2013 Jan 10.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

PKB/Akt promotes DSB repair in cancer cells through upregulating Mre11 expression following ionizing radiation.

  • Authors : Deng R; State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou, China.; Tang J

Subjects: DNA Breaks, Double-Stranded/DNA Breaks, Double-Stranded/DNA Breaks, Double-Stranded/*radiation effects ; DNA Repair/DNA Repair/DNA Repair/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*biosynthesis

  • Source: Oncogene [Oncogene] 2011 Feb 24; Vol. 30 (8), pp. 944-55. Date of Electronic Publication: 2010 Oct 18.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Evidence that the Nijmegen breakage syndrome protein, an early sensor of double-strand DNA breaks (DSB), is involved in HIV-1 post-integration repair by recruiting the ataxia telangiectasia-mutated kinase in a process similar to, but distinct from, cellular DSB repair.

  • Authors : Smith JA; Division of Infectious Diseases - Center for Human Virology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA. ; Wang FX

Subjects: Cell Cycle Proteins/Cell Cycle Proteins/Cell Cycle Proteins/*metabolism ; Cell Nucleus/Cell Nucleus/Cell Nucleus/*physiology ; DNA Repair/DNA Repair/DNA Repair/*physiology

  • Source: Virology journal [Virol J] 2008 Jan 22; Vol. 5, pp. 11. Date of Electronic Publication: 2008 Jan 22.Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X

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Academic Journal

High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway.

  • Authors : Bishop DK; Department of Radiation and Cellular Oncology, University of Chicago, Chicago IL 60637, USA. ; Nikolski Y

Subjects: Cell Cycle Proteins* ; DNA Repair* ; Meiosis*

  • Source: Genes to cells : devoted to molecular & cellular mechanisms [Genes Cells] 1999 Aug; Vol. 4 (8), pp. 425-44.Publisher: Blackwell Science Ltd Country of Publication: England NLM ID: 9607379 Publication Model: Print Cited Medium: Print ISSN: 1356-9597

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Academic Journal

Ku70/80 gene expression and DNA-dependent protein kinase (DNA-PK) activity do not correlate with double-strand break (dsb) repair capacity and cellular radiosensitivity in normal human fibroblasts.

  • Authors : Kasten U; Institute of Biophysics and Radiobiology, University of Hamburg, Germany.; Plottner N

Subjects: Antigens, Nuclear* ; DNA Helicases*; DNA Damage/DNA Damage/DNA Damage/*genetics

  • Source: British journal of cancer [Br J Cancer] 1999 Mar; Vol. 79 (7-8), pp. 1037-41.Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print Cited Medium:

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