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  • 1-10 ل  419 نتائج ل ""CHECKPOINT kinase 1""

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Subject : dna-binding proteins
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Academic Journal

Interaction of DDB1 with NBS1 in a DNA Damage Checkpoint Pathway.

  • Authors : Lim HE; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Republic of Korea.; Research Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea.

Subjects: Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/metabolism ; Cell Cycle Proteins*/Cell Cycle Proteins*/Cell Cycle Proteins*/genetics ; DNA Damage*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Dec 05; Vol. 25 (23). Date of Electronic Publication: 2024 Dec 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Mono-ubiquitination of TopBP1 by PHRF1 enhances ATR activation and genomic stability.

  • Authors : Zhao F; College of Biology, Hunan University, Changsha 410082, China.; Cai C

Subjects: Genomic Instability* ; Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/metabolism ; Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/Ataxia Telangiectasia Mutated Proteins*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Feb 27; Vol. 53 (5).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

APE1 assembles biomolecular condensates to promote the ATR-Chk1 DNA damage response in nucleolus.

  • Authors : Li J; Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC 28223, USA.; Zhao H

Subjects: DNA-Binding Proteins*/DNA-Binding Proteins*/DNA-Binding Proteins*/genetics ; Nuclear Proteins*/Nuclear Proteins*/Nuclear Proteins*/metabolism; Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/Ataxia Telangiectasia Mutated Proteins/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2022 Oct 14; Vol. 50 (18), pp. 10503-10525.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells.

  • Authors : Biayna J; Genome Data Science, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Garcia-Cao I

Subjects: Adenocarcinoma of Lung/Adenocarcinoma of Lung/Adenocarcinoma of Lung/*genetics ; Cytidine Deaminase/Cytidine Deaminase/Cytidine Deaminase/*genetics ; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*genetics

  • Source: PLoS biology [PLoS Biol] 2021 Mar 31; Vol. 19 (3), pp. e3001176. Date of Electronic Publication: 2021 Mar 31 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Structure-function analysis of TOPBP1's role in ATR signaling using the DSB-mediated ATR activation in Xenopus egg extracts (DMAX) system.

  • Authors : Montales K; Molecular and Computational Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA.; Kim A

Subjects: DNA Breaks, Double-Stranded* ; Ovum* ; Tissue Extracts*

  • Source: Scientific reports [Sci Rep] 2021 Jan 11; Vol. 11 (1), pp. 467. Date of Electronic Publication: 2021 Jan 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

RAD51 and mitotic function of mus81 are essential for recovery from low-dose of camptothecin in the absence of the WRN exonuclease.

  • Authors : Aiello FA; Mechanisms, Biomarkers and Models Unit, Department of Environment and Health, Istituto Superiore di Sanità, Roma, Italy.; Palma A

Subjects: Camptothecin/Camptothecin/Camptothecin/*pharmacology ; DNA Replication/DNA Replication/DNA Replication/*drug effects ; DNA, Single-Stranded/DNA, Single-Stranded/DNA, Single-Stranded/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2019 Jul 26; Vol. 47 (13), pp. 6796-6810.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

RNF8 mediates NONO degradation following UV-induced DNA damage to properly terminate ATR-CHK1 checkpoint signaling.

  • Authors : Deshar R; Department of Medical Lifesciences, The Catholic University of Korea, Seoul 137-701, Korea.; Yoo W

Subjects: DNA Damage*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Nuclear Matrix-Associated Proteins/Nuclear Matrix-Associated Proteins/Nuclear Matrix-Associated Proteins/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2019 Jan 25; Vol. 47 (2), pp. 762-778.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Cip29 is phosphorylated following activation of the DNA damage response in Xenopus egg extracts.

  • Authors : Holden J; Lancaster Medical School, Faculty of Health and Medicine, Lancaster University, Lancaster, United Kingdom.; Taylor EM

Subjects: DNA Repair*; DNA-Binding Proteins/DNA-Binding Proteins/DNA-Binding Proteins/*metabolism ; Xenopus/Xenopus/Xenopus/*metabolism

  • Source: PloS one [PLoS One] 2017 Jul 17; Vol. 12 (7), pp. e0181131. Date of Electronic Publication: 2017 Jul 17 (Print Publication: 2017).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

SPRTN Protease and Checkpoint Kinase 1 Cross-Activation Loop Safeguards DNA Replication

Subjects: DNA Replication; Models, Genetic; Science

  • Source: Nat CommunNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)Nature Communications

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Academic Journal

Mus81 knockdown improves chemosensitivity of hepatocellular carcinoma cells by inducing S-phase arrest and promoting apoptosis through CHK1 pathway.

  • Authors : Wu F; Department of Hepatobiliary Surgery, Guangzhou Red Cross Hospital /Fourth Affiliated Hospital of Jinan University, Tongfu Roud 396, Guangzhou, 510220, China.; Chen WJ

Subjects: Signal Transduction*; Apoptosis/Apoptosis/Apoptosis/*genetics ; Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics

  • Source: Cancer medicine [Cancer Med] 2016 Feb; Vol. 5 (2), pp. 370-85. Date of Electronic Publication: 2015 Dec 29.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print-Electronic Cited Medium: Internet

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  • 1-10 ل  419 نتائج ل ""CHECKPOINT kinase 1""