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Academic Journal

CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade.

  • Authors : Rogers CM; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Kaur H

Subjects: DNA Breaks, Double-Stranded* ; Telomere-Binding Proteins*/Telomere-Binding Proteins*/Telomere-Binding Proteins*/metabolism ; Telomere-Binding Proteins*/Telomere-Binding Proteins*/Telomere-Binding Proteins*/genetics

  • Source: Science (New York, N.Y.) [Science] 2025 May 22; Vol. 388 (6749), pp. 881-888. Date of Electronic Publication: 2025 May 22.Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic

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Academic Journal

Role of MRE11 in DNA damage repair pathway dynamics and its diagnostic and prognostic significance in hereditary breast and ovarian cancer.

  • Authors : Tarapara B; Department of Life-Science, Gujarat University and Young Scientist (DHR-ICMR), Molecular Diagnostic & Research Lab-3, Department of Cancer Biology, The Gujarat Cancer & Research Institute, Ahmedabad, Gujarat, 380016, India.; Shah F

Subjects: MRE11 Homologue Protein*/MRE11 Homologue Protein*/MRE11 Homologue Protein*/genetics ; MRE11 Homologue Protein*/MRE11 Homologue Protein*/MRE11 Homologue Protein*/metabolism ; DNA Repair*/DNA Repair*/DNA Repair*/genetics

  • Source: BMC cancer [BMC Cancer] 2025 Apr 09; Vol. 25 (1), pp. 650. Date of Electronic Publication: 2025 Apr 09.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Low levels of DNA repair enzyme NEIL2 May exacerbate inflammation and genomic damage in subjects with stable COPD and during severe exacerbations.

  • Authors : Cardenas VJ Jr; Division of Pulmonary, Critical Care and Sleep Medicine, University of Texas Medical Branch, 301 University Blvd, Galveston, TX, 77555-0561, USA. .; Institute for Translational Sciences, University of Texas Medical Branch, Galveston, TX, USA. .

Subjects: Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/genetics ; Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/blood ; Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/Pulmonary Disease, Chronic Obstructive*/diagnosis

  • Source: Respiratory research [Respir Res] 2025 Apr 28; Vol. 26 (1), pp. 165. Date of Electronic Publication: 2025 Apr 28.Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Archaeal replicative primase mediates DNA double-strand break repair.

  • Authors : Xiong D; State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, No. 1 West Beichen Road, Chaoyang District, Beijing 100101, China.; College of Life Science, University of Chinese Academy of Sciences, Beijing100049, China.

Subjects: DNA Breaks, Double-Stranded* ; DNA Primase*/DNA Primase*/DNA Primase*/metabolism ; DNA Primase*/DNA Primase*/DNA Primase*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Apr 22; Vol. 53 (8).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

DNA repair and the contribution to chemotherapy resistance.

  • Authors : Nesic K; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.

Subjects: DNA Repair* ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/drug therapy

  • Source: Genome medicine [Genome Med] 2025 May 26; Vol. 17 (1), pp. 62. Date of Electronic Publication: 2025 May 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X

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Academic Journal

Comparative analysis of multiple DNA double-strand break repair pathways in CRISPR-mediated endogenous tagging.

  • Authors : Tei C; Department of Physiological Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Bunkyo, Tokyo, Japan.; Hata S

Subjects: DNA Breaks, Double-Stranded* ; CRISPR-Cas Systems* ; DNA End-Joining Repair*

  • Source: Communications biology [Commun Biol] 2025 May 13; Vol. 8 (1), pp. 749. Date of Electronic Publication: 2025 May 13.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer.

  • Authors : He X; Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.; Li Y

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/drug therapy ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism

  • Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2025 Apr; Vol. 12 (14), pp. e2413121. Date of Electronic Publication: 2025 Feb 14.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Academic Journal

Bypass of Methoxyamine-Adducted Abasic Sites by Eukaryotic Translesion DNA Polymerases.

  • Authors : Yudkina AV; Siberian Branch of the Russian Academy of Sciences Institute of Chemical Biology and Fundamental Medicine, 8 Lavrentieva Ave., 630090 Novosibirsk, Russia.; Department of Natural Sciences, Novosibirsk State University, 2 Pirogova St., 630090 Novosibirsk, Russia.

Subjects: DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/metabolism ; DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/genetics ; Hydroxylamines*/Hydroxylamines*/Hydroxylamines*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2025 Jan 14; Vol. 26 (2). Date of Electronic Publication: 2025 Jan 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The linker region of a development-specific DNA polymerase X ensures efficient repair of programmed DNA double-strand breaks in Parameciumtetraurelia.

  • Authors : Verron B; Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198 Gif-sur-Yvette cedex, France.; Arnaiz O

Subjects: DNA Breaks, Double-Stranded* ; DNA End-Joining Repair* ; DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/DNA-Directed DNA Polymerase*/genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2025 Apr 10; Vol. 53 (7).Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Dynamic interplay of cNHEJ and MMEJ pathways of DNA double-strand break repair during embryonic development in zebrafish.

  • Authors : Carrara M; Physiologie Moléculaire et Adaptation (PhyMA, UMR7221), Muséum national d'Histoire naturelle, CNRS, Paris, France.; Structure and Instability of Genomes Laboratory (StrING UMR7196 - U1154), Muséum national d'Histoire naturelle, CNRS, INSERM, Paris, France.

Subjects: Zebrafish*/Zebrafish*/Zebrafish*/genetics ; Zebrafish*/Zebrafish*/Zebrafish*/embryology ; DNA Breaks, Double-Stranded*

  • Source: Scientific reports [Sci Rep] 2025 Feb 10; Vol. 15 (1), pp. 4886. Date of Electronic Publication: 2025 Feb 10.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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