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Academic Journal

POLE/POLD1 mutation and tumor immunotherapy.

  • Authors : Ma X; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.; Dong L

Subjects: DNA Polymerase II*/DNA Polymerase II*/DNA Polymerase II*/genetics ; DNA Polymerase II*/DNA Polymerase II*/DNA Polymerase II*/metabolism ; DNA Polymerase III*/DNA Polymerase III*/DNA Polymerase III*/genetics

  • Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2022 Jul 02; Vol. 41 (1), pp. 216. Date of Electronic Publication: 2022 Jul 02.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Academic Journal

Frequency and patterns of ribonucleotide incorporation around autonomously replicating sequences in yeast reveal the division of labor of replicative DNA polymerases.

  • Authors : Xu P; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.; Storici F

Subjects: DNA Replication*; DNA Polymerase II/DNA Polymerase II/DNA Polymerase II/*metabolism ; DNA Polymerase III/DNA Polymerase III/DNA Polymerase III/*metabolism

  • Source: Nucleic acids research [Nucleic Acids Res] 2021 Oct 11; Vol. 49 (18), pp. 10542-10557.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

POLE and POLD1 germline exonuclease domain pathogenic variants, a rare event in colorectal cancer from the Middle East.

  • Authors : Siraj AK; Human Cancer Genomic Research, Research Center, King Faisal Specialist Hospital and Research Center, iyadh, Saudi Arabia.; Bu R

Subjects: Germ-Line Mutation*; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics ; DNA Polymerase II/DNA Polymerase II/DNA Polymerase II/*genetics

  • Source: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2020 Aug; Vol. 8 (8), pp. e1368. Date of Electronic Publication: 2020 Jun 22.Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101603758 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Low frequency of POLD1 and POLE exonuclease domain variants in patients with multiple colorectal polyps.

Subjects: Mutation Rate*; Colonic Polyps/Colonic Polyps/Colonic Polyps/*genetics ; Colorectal Neoplasms/Colorectal Neoplasms/Colorectal Neoplasms/*genetics

  • Source: Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2019 Apr; Vol. 7 (4), pp. e00603. Date of Electronic Publication: 2019 Mar 02.Publisher: John Wiley & Sons Country of Publication: United States NLM ID: 101603758 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Report

POLE/POLD1 mutation in non-exonuclease domain matters for predicting efficacy of immune-checkpoint-inhibitor therapy.

  • Authors : Chen YX; State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, 510060, China.; Wang ZX

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/genetics ; Neoplasms*/Neoplasms*/Neoplasms*/mortality

  • Source: Clinical and translational medicine [Clin Transl Med] 2021 Sep; Vol. 11 (9), pp. e524.Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326

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Academic Journal

Exchange between Escherichia coli polymerases II and III on a processivity clamp.

  • Authors : Kath JE; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.; Chang S

Subjects: DNA/DNA/DNA/*biosynthesis ; DNA Polymerase II/DNA Polymerase II/DNA Polymerase II/*genetics ; DNA Polymerase III/DNA Polymerase III/DNA Polymerase III/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2016 Feb 29; Vol. 44 (4), pp. 1681-90. Date of Electronic Publication: 2015 Dec 10.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Mismatch repair and DNA polymerase δ proofreading prevent catastrophic accumulation of leading strand errors in cells expressing a cancer-associated DNA polymerase ϵ variant.

  • Authors : Bulock CR; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.; Xing X

Subjects: DNA Mismatch Repair/DNA Mismatch Repair/DNA Mismatch Repair/*genetics ; DNA Polymerase II/DNA Polymerase II/DNA Polymerase II/*genetics ; DNA Polymerase III/DNA Polymerase III/DNA Polymerase III/*genetics

  • Source: Nucleic acids research [Nucleic Acids Res] 2020 Sep 18; Vol. 48 (16), pp. 9124-9134.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

DNA Polymerases as targets for gene therapy of hepatocellular carcinoma.

  • Authors : Liu H; Institute of Occupational Diseases, Zhejiang Academy of Medical Sciences, 182 Tianmushan Road, Hangzhou, 310013, Zhejiang, P.R. China. .; Wei Q

Subjects: Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/Carcinoma, Hepatocellular/*genetics ; DNA Polymerase I/DNA Polymerase I/DNA Polymerase I/*genetics ; DNA Polymerase II/DNA Polymerase II/DNA Polymerase II/*genetics

  • Source: BMC cancer [BMC Cancer] 2015 Apr 29; Vol. 15, pp. 325. Date of Electronic Publication: 2015 Apr 29.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Academic Journal

Comprehensive analysis of POLE and POLD1 Gene Variations identifies cancer patients potentially benefit from immunotherapy in Chinese population.

  • Authors : Yao J; HaploX Biotechnology, Co., Ltd, Shenzhen, P.R. China.; Gong Y

Subjects: Databases, Nucleic Acid* ; Immunotherapy* ; Lung Neoplasms*/Lung Neoplasms*/Lung Neoplasms*/genetics

  • Source: Scientific reports [Sci Rep] 2019 Oct 31; Vol. 9 (1), pp. 15767. Date of Electronic Publication: 2019 Oct 31.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Genomic relationship between SINE retrotransposons, Pol III-Pol II transcription, and chromatin organization: the journey from junk to jewel.

  • Authors : Lunyak VV; Buck Institute for Age Research, Novato, CA 94945, USA. ; Atallah M

Subjects: Genome*; Chromatin/Chromatin/Chromatin/*chemistry ; DNA Polymerase II/DNA Polymerase II/DNA Polymerase II/*metabolism

  • Source: Biochemistry and cell biology = Biochimie et biologie cellulaire [Biochem Cell Biol] 2011 Oct; Vol. 89 (5), pp. 495-504. Date of Electronic Publication: 2011 Sep 14.Publisher: Canadian Science Publishing Country of Publication: Canada NLM ID: 8606068 Publication Model: Print-Electronic Cited Medium: Internet

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