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Exploring the role of PARP1 inhibition in enhancing antibody-drug conjugate therapy for acute leukemias: insights from DNA damage response pathway interactions.

• Authors : Ghelli Luserna di Rorà A; Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Via Piero Maroncelli, 40, 47014, Meldola, FC, Italy.; Fondazione Pisana per la Scienza ONLUS, San Giuliano Terme, Italy.

Subjects: DNA Damage* ; Immunoconjugates*/Immunoconjugates*/Immunoconjugates*/pharmacology ; Immunoconjugates*/Immunoconjugates*/Immunoconjugates*/therapeutic use

• Source: Journal of translational medicine [J Transl Med] 2024 Nov 26; Vol. 22 (1), pp. 1062. Date of Electronic Publication: 2024 Nov 26.Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876

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The DNA damage response pathway regulates the expression of the immune checkpoint CD47.

• Authors : Ghantous L; Goldyne Savad Institute of Gene Therapy, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.; Department of Nephrology and Hypertension, Hadassah Medical Center, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.

Subjects: CD47 Antigen*/CD47 Antigen*/CD47 Antigen*/genetics ; DNA Damage* ; Liver*

• Source: Communications biology [Commun Biol] 2023 Mar 07; Vol. 6 (1), pp. 245. Date of Electronic Publication: 2023 Mar 07.Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN:

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Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway.

• Authors : Sui X; Department of Physiology & Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, China.; Zhang C

Subjects: DNA Damage*; Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/Antineoplastic Agents, Phytogenic/*pharmacology ; Gene Regulatory Networks/Gene Regulatory Networks/Gene Regulatory Networks/*drug effects

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2017 Sep 26; Vol. 36 (1), pp. 133. Date of Electronic Publication: 2017 Sep 26.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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A Mathematical Model to Investigate the Effects of Ceralasertib and Olaparib in Targeting the Cellular DNA Damage Response Pathway

• Authors : Kira Pugh; Michael Davies; Gibin Powathil

Subjects: Cell Line, Tumor; Phthalazines; Poly(ADP-ribose) Polymerase Inhibitors

• Source: The Journal of Pharmacology and Experimental Therapeutics. 387:55-65

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The DNA damage sensor ATM kinase interacts with the p53 mRNA and guides the DNA damage response pathway.

• Authors : Karakostis, Konstantinos^1,2 (AUTHOR) ; Malbert-Colas, Laurence¹ (AUTHOR); Thermou, Aikaterini¹ (AUTHOR)

• Source: Molecular Cancer. 1/23/2024, Vol. 23, p1-12. 12p.

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Activation of the DNA damage response pathway in the infected gastric tissue with Helicobacter pylori: a case-control study

• Authors : Amiratabak Rajaei; Armin Ghameshlou; Reza Shirkoohi

Subjects: Helicobacter pylori; Stomach Neoplasms; Case-Control Studies

• Source: The Journal of Infection in Developing Countries. 17:1125-1129

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Interactome Analysis Reveals that Heterochromatin Protein 1γ (HP1γ) Is Associated with the DNA Damage Response Pathway.

• Authors : Kim H; Department of Biological Sciences, Sungkyunkwan University, Suwon, Korea ; Genomic Instability Research Center, Ajou University School of Medicine, Suwon, Korea.

Subjects: DNA Damage* ; Protein Interaction Maps*; Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/Chromosomal Proteins, Non-Histone/*metabolism

• Source: Cancer research and treatment [Cancer Res Treat] 2016 Jan; Vol. 48 (1), pp. 322-33. Date of Electronic Publication: 2015 Mar 06.Publisher: Korean Cancer Association Country of Publication: Korea (South) NLM ID: 101155137 Publication Model: Print-Electronic Cited Medium: Internet

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Monitoring the Activation of the DNA Damage Response Pathway in a 3D Spheroid Model.

• Authors : Mondesert O; Université de Toulouse; ITAV-USR3505, F-31106 Toulouse, France

Subjects: DNA Damage* ; Models, Biological*; HEK293 Cells

• Source: PloS one [PLoS One] 2015 Jul 30; Vol. 10 (7), pp. e0134411. Date of Electronic Publication: 2015 Jul 30 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Inactivation of PNKP by mutant ATXN3 triggers apoptosis by activating the DNA damage-response pathway in SCA3.

• Authors : Gao R; Department of Neurology, University of Texas Medical Branch, Galveston, Texas, United States of America.; Liu Y

Subjects: DNA Damage/DNA Damage/DNA Damage/*genetics ; DNA Repair Enzymes/DNA Repair Enzymes/DNA Repair Enzymes/*genetics ; Machado-Joseph Disease/Machado-Joseph Disease/Machado-Joseph Disease/*genetics

• Source: PLoS genetics [PLoS Genet] 2015 Jan 15; Vol. 11 (1), pp. e1004834. Date of Electronic Publication: 2015 Jan 15 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet

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Fusobacterium nucleatum promotes esophageal squamous cell carcinoma progression and chemoresistance by enhancing the secretion of chemotherapy-induced senescence-associated secretory phenotype via activation of DNA damage response pathway

• Authors : Jian-Wei Zhang; Dan Zhang; Hai-Sen Yin

Subjects: Fusobacterium nucleatum; Esophageal Neoplasms; chemoresistance

• Source: Gut MicrobesGut Microbes, Vol 15, Iss 1 (2023)

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