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Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice.

• Authors : Wells AE; The Jackson Laboratory, Bar Harbor, ME, United States of America.; Wilson JJ

Subjects: Deoxyglucose*/Deoxyglucose*/Deoxyglucose*/pharmacology ; Deoxyglucose*/Deoxyglucose*/Deoxyglucose*/metabolism ; Epilepsy*

• Source: PloS one [PLoS One] 2024 Mar 07; Vol. 19 (3), pp. e0299595. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Application of the 2-deoxyglucose scaffold as a new chiral probe for elucidation of the absolute configuration of secondary alcohols.

• Authors : Trocka A; Department of Organic Chemistry, Faculty of Chemistry, Gdańsk University of Technology, Narutowicza Street 11/12, 80-233, Gdańsk, Poland. .; Szwarc-Karabyka K

Subjects: Alcohols*/Alcohols*/Alcohols*/chemistry ; Deoxyglucose*; Carbon

• Source: Scientific reports [Sci Rep] 2022 Oct 07; Vol. 12 (1), pp. 16838. Date of Electronic Publication: 2022 Oct 07.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Novel mutation in hexokinase 2 confers resistance to 2-deoxyglucose by altering protein dynamics.

• Authors : Hellemann E; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.; Walker JL

Subjects: Deoxyglucose*/Deoxyglucose*/Deoxyglucose*/metabolism ; Hexokinase*/Hexokinase*/Hexokinase*/genetics ; Hexokinase*/Hexokinase*/Hexokinase*/metabolism

• Source: PLoS computational biology [PLoS Comput Biol] 2022 Mar 02; Vol. 18 (3), pp. e1009929. Date of Electronic Publication: 2022 Mar 02 (Print Publication: 2022).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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A Phase I/II Trial of 2-Deoxyglucose (2DG) for the Treatment of Advanced Cancer and Hormone Refractory Prostate Cancer (2-Deoxyglucose)

• Authors : United States Department of Defense

• Source: A Phase I/II Trial of 2-Deoxyglucose (2DG) for the Treatment of Advanced Cancer and Hormone Refractory Prostate Cancer

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Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon cancer.

• Authors : Yoon JK; Department of Nuclear Medicine and Molecular Imaging, Ajou University School of Medicine, Suwon, Republic of Korea.; Byeon HE

Subjects: Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*pharmacology ; Antineoplastic Agents/Antineoplastic Agents/Antineoplastic Agents/*therapeutic use ; Cell Cycle Checkpoints/Cell Cycle Checkpoints/Cell Cycle Checkpoints/*drug effects

• Source: Scientific reports [Sci Rep] 2020 Mar 13; Vol. 10 (1), pp. 4713. Date of Electronic Publication: 2020 Mar 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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[ 13 C 6 ,D 8 ]2-deoxyglucose phosphorylation by hexokinase shows selectivity for the β-anomer.

• Authors : Sapir G; Department of Radiology, Hadassah Medical Center, Hebrew University of Jerusalem, The Faculty of Medicine, Jerusalem, Israel.; Harris T

Subjects: Deoxyglucose/Deoxyglucose/Deoxyglucose/*metabolism ; Hexokinase/Hexokinase/Hexokinase/*metabolism; Bacterial Proteins/Bacterial Proteins/Bacterial Proteins/metabolism

• Source: Scientific reports [Sci Rep] 2019 Dec 23; Vol. 9 (1), pp. 19683. Date of Electronic Publication: 2019 Dec 23.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Novel Targeted Anti-Tumor Nanoparticles Developed from Folic Acid-Modified 2-Deoxyglucose.

• Authors : Jin S; Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, China. .; National Institutes for Food and Drug Control, Beijing 100050, China. .

Subjects: Deoxyglucose*/Deoxyglucose*/Deoxyglucose*/chemistry ; Folic Acid*/Folic Acid*/Folic Acid*/chemistry ; Nanoparticles*/Nanoparticles*/Nanoparticles*/chemistry

• Source: International journal of molecular sciences [Int J Mol Sci] 2019 Feb 06; Vol. 20 (3). Date of Electronic Publication: 2019 Feb 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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The combination of metformin and 2-deoxyglucose significantly inhibits cyst formation in miniature pigs with polycystic kidney disease.

• Authors : Lian X; Department of Nephrology, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Diseases, Chinese PLA General Hospital, Beijing, China.; Department of Nephrology, Beijing Luhe Hospital, Capital Medical University, Beijing, China.

Subjects: Deoxyglucose/Deoxyglucose/Deoxyglucose/*therapeutic use ; Metformin/Metformin/Metformin/*therapeutic use ; Polycystic Kidney, Autosomal Dominant/Polycystic Kidney, Autosomal Dominant/Polycystic Kidney, Autosomal Dominant/*drug therapy

• Source: British journal of pharmacology [Br J Pharmacol] 2019 Mar; Vol. 176 (5), pp. 711-724. Date of Electronic Publication: 2019 Jan 10.Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381

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Rescue of 2-Deoxyglucose Side Effects by Ketogenic Diet.

• Authors : Voss M; Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Schleusenweg 2-16, 60528 Frankfurt am Main, Germany. .; University Cancer Center Frankfurt (UCT), University Hospital Frankfurt, Goethe University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. .

Subjects: Antimetabolites/Antimetabolites/Antimetabolites/*adverse effects ; Deoxyglucose/Deoxyglucose/Deoxyglucose/*adverse effects ; Diet, Ketogenic/Diet, Ketogenic/Diet, Ketogenic/*methods

• Source: International journal of molecular sciences [Int J Mol Sci] 2018 Aug 20; Vol. 19 (8). Date of Electronic Publication: 2018 Aug 20.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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2-Deoxyglucose Suppresses ERK Phosphorylation in LKB1 and Ras Wild-Type Non-Small Cell Lung Cancer Cells.

• Authors : Sun L; Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Lung Cancer Institute, Tianjin Medical University General Hospital, Tianjin, P.R. China.; Liu X

Subjects: Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/Carcinoma, Non-Small-Cell Lung/*pathology ; Deoxyglucose/Deoxyglucose/Deoxyglucose/*pharmacology ; Extracellular Signal-Regulated MAP Kinases/Extracellular Signal-Regulated MAP Kinases/Extracellular Signal-Regulated MAP Kinases/*metabolism

• Source: PloS one [PLoS One] 2016 Dec 29; Vol. 11 (12), pp. e0168793. Date of Electronic Publication: 2016 Dec 29 (Print Publication: 2016).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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