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  • 1-10 ل  766 نتائج ل ""CYP3A""

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Subject : cytochrome p-450 enzyme system
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Academic Journal

Equilibrium landscape of ingress/egress channels and gating residues of the Cytochrome P450 3A4.

  • Authors : Ackad EM; Department of Physics, Southern Illinois University Edwardsville, Edwardsville, IL, United States of America.; Biggers L

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism; Drug Interactions

  • Source: PloS one [PLoS One] 2024 Mar 18; Vol. 19 (3), pp. e0298424. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Synthesis of mono Cytochrome P450 in a modified CHO-CPR cell-free protein production platform.

  • Authors : Knauer JF; Fraunhofer Project Group PZ-Syn of the Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses (IZI-BB), Potsdam, Germany.; Fraunhofer Institute for Cell Therapy and Immunology (IZI), Branch Bioanalytics and Bioprocesses (IZI-BB), Potsdam, Germany.

Subjects: Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism; Animals

  • Source: Scientific reports [Sci Rep] 2024 Jan 13; Vol. 14 (1), pp. 1271. Date of Electronic Publication: 2024 Jan 13.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Predictability of human exposure by human-CYP3A4-transgenic mouse models: A meta-analysis.

  • Authors : Damoiseaux D; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.; Schinkel AH

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism; Humans

  • Source: Clinical and translational science [Clin Transl Sci] 2024 Jan; Vol. 17 (1), pp. e13668. Date of Electronic Publication: 2023 Dec 01.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

The roles of CYP2C19 and CYP3A4 in the in vitro metabolism of β-eudesmol in human liver: Reaction phenotyping and enzyme kinetics.

  • Authors : Muhamad N; Graduate Studies, Chulabhorn International College of Medicine, Thammasat University, Pathumthani, Thailand.; Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Thammasat University, Pathumthani, Thailand.

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism; Humans

  • Source: Pharmacology research & perspectives [Pharmacol Res Perspect] 2023 Dec; Vol. 11 (6), pp. e01149.Publisher: John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States

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Academic Journal

Effects of drug-drug interactions and CYP3A4 variants on alectinib metabolism.

  • Authors : Liu YN; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.; Chen J

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism

  • Source: Archives of toxicology [Arch Toxicol] 2023 Aug; Vol. 97 (8), pp. 2133-2142. Date of Electronic Publication: 2023 May 20.Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Stable Chinese Hamster Ovary Suspension Cell Lines Harboring Recombinant Human Cytochrome P450 Oxidoreductase and Human Cytochrome P450 Monooxygenases as Platform for In Vitro Biotransformation Studies.

  • Authors : Schulz C; Fraunhofer Project Group PZ-Syn, Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses (IZI-BB) Located at the Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.; Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, Germany.

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Cytochrome P-450 Enzyme System*; Animals

  • Source: Cells [Cells] 2023 Aug 24; Vol. 12 (17). Date of Electronic Publication: 2023 Aug 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409

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Academic Journal

In Vitro Investigations into the Potential Drug Interactions of Pseudoginsenoside DQ Mediated by Cytochrome P450 and Human Drug Transporters.

  • Authors : Li Z; School of Pharmaceutical Sciences, Jilin University, 126 Xinmin Street, Changchun 130021, China.; Wang C

Subjects: Ginsenosides*/Ginsenosides*/Ginsenosides*/pharmacology ; Ginsenosides*/Ginsenosides*/Ginsenosides*/chemistry ; Drug Interactions*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 May 24; Vol. 29 (11). Date of Electronic Publication: 2024 May 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

In vivo evaluation of intestinal human CYP3A inhibition by macrolide antibiotics in CYP3A-humanised mice.

  • Authors : Minegishi G; Laboratory of DDS Design and Drug Disposition, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.; Kazuki Y

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/genetics ; Cytochrome P-450 Enzyme System*; Anti-Bacterial Agents/Anti-Bacterial Agents/Anti-Bacterial Agents/pharmacology

  • Source: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2021 Jul; Vol. 51 (7), pp. 764-770. Date of Electronic Publication: 2021 May 20.Publisher: Informa Healthcare Country of Publication: England NLM ID: 1306665 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Predicting changes in the pharmacokinetics of CYP3A-metabolized drugs in hepatic impairment and insights into factors driving these changes.

  • Authors : Ladumor MK; Department of Pharmaceutics, University of Washington School of Pharmacy, Seattle, Washington, USA.; Storelli F

Subjects: Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/Cytochrome P-450 CYP3A*/metabolism ; Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/Cytochrome P-450 Enzyme System*/metabolism; Humans

  • Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Feb; Vol. 12 (2), pp. 261-273. Date of Electronic Publication: 2022 Dec 20.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Hydroxylated Tetramethoxyflavone Affects Intestinal Cell Permeability and Inhibits Cytochrome P450 Enzymes.

  • Authors : Jan KC; Department of Food Science, National Pingtung University of Science and Technology, No. 1, Xuefu Rd, Neipu, Pingtung 91201, Taiwan.; Gavahian M

Subjects: Cytochrome P-450 Enzyme System* ; Citrus*; Humans

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Jan 09; Vol. 29 (2). Date of Electronic Publication: 2024 Jan 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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  • 1-10 ل  766 نتائج ل ""CYP3A""