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Academic Journal

Pharmacological Targeting of the ER-Resident Chaperones GRP94 or Cyclophilin B Induces Secretion of IL-22 Binding Protein Isoform-1 (IL-22BPi1).

  • Authors : Gómez-Fernández P; Neurogenomiks Group, Department of Neuroscience, University of the Basque Country (UPV/EHU), 48490 Leioa, Spain. .; Urtasun A

Subjects: Benzoquinones/Benzoquinones/Benzoquinones/*pharmacology ; Cyclophilins/Cyclophilins/Cyclophilins/*metabolism ; Cyclosporine/Cyclosporine/Cyclosporine/*pharmacology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 May 17; Vol. 20 (10). Date of Electronic Publication: 2019 May 17.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability.

  • Authors : Yau WL; G5 Virulence Parasitaire, Institut Pasteur and CNRS URA 2581, Paris, France.; Blisnick T

Subjects: Cyclophilins/Cyclophilins/Cyclophilins/*physiology ; Cyclosporine/Cyclosporine/Cyclosporine/*pharmacology ; Leishmania donovani/Leishmania donovani/Leishmania donovani/*drug effects

  • Source: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2010 Jun 29; Vol. 4 (6), pp. e729. Date of Electronic Publication: 2010 Jun 29.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Inhibition of cyclophilins alters lipid trafficking and blocks hepatitis C virus secretion.

  • Authors : Anderson LJ; Novartis Institutes for Biomedical Research, Inc Cambridge, Massachusetts 02139, USA.; Lin K

Subjects: Virus Release*; Antiviral Agents/Antiviral Agents/Antiviral Agents/*metabolism ; Apolipoproteins B/Apolipoproteins B/Apolipoproteins B/*metabolism

  • Source: Virology journal [Virol J] 2011 Jun 28; Vol. 8, pp. 329. Date of Electronic Publication: 2011 Jun 28.Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X

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Academic Journal

Pharmacological Cyclophilin Inhibitors Prevent Intoxication of Mammalian Cells with Bordetella pertussis Toxin.

  • Authors : Ernst K; Institute of Pharmacology and Toxicology, University of Ulm Medical Center, 89081 Ulm, Germany. .; Eberhardt N

Subjects: Cyclophilins/Cyclophilins/Cyclophilins/*antagonists & inhibitors ; Cyclosporine/Cyclosporine/Cyclosporine/*pharmacology ; Pertussis Toxin/Pertussis Toxin/Pertussis Toxin/*toxicity

  • Source: Toxins [Toxins (Basel)] 2018 May 01; Vol. 10 (5). Date of Electronic Publication: 2018 May 01.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651

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Academic Journal

Discovery of non-peptidic small molecule inhibitors of cyclophilin D as neuroprotective agents in Aβ-induced mitochondrial dysfunction.

  • Authors : Park I; Convergence Research Center for Diagnosis, Treatment and Care System of Dementia, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul, 02792, Republic of Korea.; Department of Biotechnology, Yonsei University, Seoul, 03722, Republic of Korea.

Subjects: Cyclophilins/Cyclophilins/Cyclophilins/*antagonists & inhibitors ; Cyclosporine/Cyclosporine/Cyclosporine/*chemistry ; Mitochondria/Mitochondria/Mitochondria/*drug effects

  • Source: Journal of computer-aided molecular design [J Comput Aided Mol Des] 2017 Oct; Vol. 31 (10), pp. 929-941. Date of Electronic Publication: 2017 Sep 14.Publisher: Springer Country of Publication: Netherlands NLM ID: 8710425 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Cyclosporine inhibits a direct interaction between cyclophilins and hepatitis C NS5A.

  • Authors : Fernandes F; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.; Ansari IU

Subjects: Cyclophilin A/Cyclophilin A/Cyclophilin A/*metabolism ; Cyclophilins/Cyclophilins/Cyclophilins/*metabolism ; Cyclosporine/Cyclosporine/Cyclosporine/*pharmacology

  • Source: PloS one [PLoS One] 2010 Mar 23; Vol. 5 (3), pp. e9815. Date of Electronic Publication: 2010 Mar 23.Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet

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Academic Journal

Cyclophilin J is a novel peptidyl-prolyl isomerase and target for repressing the growth of hepatocellular carcinoma.

  • Authors : Chen J; State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Sciences, Fudan University, Shanghai, P.R. China; Shandong Research Center of Stem Cell Engineering, Yantai Yuhuangding Hospital, Affiliated Hospital of Qingdao University, Yantai, Shandong, P.R. China.

Subjects: Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/drug therapy ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/enzymology ; Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/Carcinoma, Hepatocellular*/genetics

  • Source: PloS one [PLoS One] 2015 May 28; Vol. 10 (5), pp. e0127668. Date of Electronic Publication: 2015 May 28 (Print Publication: 2015).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

A staphylococcal cyclophilin carries a single domain and unfolds via the formation of an intermediate that preserves cyclosporin A binding activity.

  • Authors : Seal S; Department of Biochemistry, Bose Institute, Kolkata, West Bengal, India.; Polley S

Subjects: Cyclophilins/Cyclophilins/Cyclophilins/*chemistry ; Cyclophilins/Cyclophilins/Cyclophilins/*metabolism ; Cyclosporine/Cyclosporine/Cyclosporine/*pharmacology

  • Source: PloS one [PLoS One] 2019 Mar 29; Vol. 14 (3), pp. e0210771. Date of Electronic Publication: 2019 Mar 29 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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